GREMLIN.BAKERLAB.org
Powered by OPENSEQ.org
YCJV - Putative uncharacterized ABC transporter ATP-binding protein YcjV
UniProt: P77481 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13919
Length: 360 (359)
Sequences: 9017
Seq/Len: 25.12

YCJV
Paralog alert: 0.83 [within 20: 0.12] - ratio of genomes with paralogs
Cluster includes: ARTP BTUD CCMA CYSA DDPD DDPF DPPD DPPF FBPC FECE FEPC FHUC FTSE GLNQ GLTL HISP LIVF LIVG LOLD LPTB MALK METN MLAF MODC NIKD NIKE OPPD OPPF PHNC PHNK PHNL POTA POTG PROV PSTB SAPD SAPF SSUB SUFC TAUB THIQ UGPC YADG YBBA YBBL YCJV YDCT YECC YEHX YHDZ YNJD ZNUC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
217_G 221_T 4.646 1.00
34_V 202_A 4.544 1.00
120_Q 125_R 4.192 1.00
31_E 204_R 3.983 1.00
60_D 67_R 3.801 1.00
214_Q 228_N 3.761 1.00
300_A 316_T 3.405 1.00
5_S 26_E 3.322 1.00
112_D 116_N 3.198 1.00
7_Q 60_D 3.169 1.00
107_A 110_V 2.971 1.00
8_H 22_D 2.847 1.00
303_S 317_T 2.842 1.00
127_Y 130_R 2.766 1.00
21_K 212_I 2.703 1.00
94_Y 129_K 2.664 1.00
119_A 128_L 2.641 1.00
94_Y 98_A 2.609 1.00
8_H 24_N 2.566 1.00
114_R 152_E 2.547 1.00
94_Y 116_N 2.502 1.00
179_K 183_K 2.493 1.00
206_V 213_V 2.49 1.00
94_Y 115_V 2.473 1.00
118_A 150_V 2.46 1.00
64_D 154_G 2.455 1.00
33_I 206_V 2.448 1.00
218_A 221_T 2.422 1.00
299_S 338_N 2.42 1.00
49_M 61_L 2.412 1.00
301_K 338_N 2.396 1.00
63_I 68_M 2.38 1.00
66_K 154_G 2.28 1.00
94_Y 112_D 2.277 1.00
20_V 49_M 2.271 1.00
4_L 155_V 2.216 1.00
50_I 189_I 2.157 1.00
209_K 214_Q 2.11 1.00
28_A 31_E 2.103 1.00
206_V 216_V 2.101 1.00
6_L 9_I 2.098 1.00
18_H 21_K 2.066 1.00
98_A 115_V 2.051 1.00
77_N 154_G 2.047 1.00
334_H 337_E 1.986 1.00
5_S 62_L 1.985 1.00
158_M 188_M 1.98 1.00
48_R 54_E 1.977 1.00
299_S 340_T 1.947 1.00
229_M 280_V 1.947 1.00
301_K 317_T 1.927 1.00
62_L 67_R 1.92 1.00
10_Q 22_D 1.908 1.00
95_D 102_K 1.884 1.00
113_E 117_W 1.86 1.00
7_Q 62_L 1.844 1.00
122_L 146_G 1.838 1.00
123_G 172_Q 1.829 1.00
6_L 50_I 1.805 1.00
110_V 113_E 1.802 1.00
12_I 18_H 1.8 1.00
10_Q 58_G 1.79 1.00
97_M 146_G 1.783 1.00
11_K 49_M 1.768 1.00
207_I 231_V 1.768 1.00
10_Q 18_H 1.76 1.00
88_Y 100_G 1.755 1.00
98_A 111_I 1.737 1.00
111_I 115_V 1.732 1.00
11_K 54_E 1.698 1.00
66_K 71_V 1.678 1.00
246_T 278_P 1.66 1.00
223_Y 286_E 1.656 1.00
229_M 242_F 1.645 1.00
229_M 233_G 1.625 1.00
109_E 113_E 1.619 1.00
49_M 56_I 1.615 1.00
33_I 216_V 1.57 1.00
20_V 46_T 1.569 1.00
106_I 111_I 1.568 1.00
92_T 95_D 1.557 1.00
41_C 208_M 1.533 1.00
106_I 110_V 1.524 1.00
233_G 242_F 1.522 1.00
100_G 151_R 1.512 1.00
242_F 280_V 1.508 1.00
68_M 71_V 1.507 1.00
33_I 204_R 1.503 1.00
11_K 57_S 1.501 1.00
118_A 149_I 1.476 1.00
6_L 25_L 1.475 1.00
116_N 128_L 1.473 1.00
117_W 152_E 1.466 1.00
316_T 341_I 1.447 1.00
72_P 75_A 1.445 1.00
62_L 65_G 1.444 1.00
23_F 46_T 1.442 1.00
114_R 117_W 1.442 1.00
97_M 119_A 1.433 1.00
311_E 326_R 1.429 1.00
244_R 278_P 1.425 1.00
110_V 114_R 1.411 1.00
92_T 131_K 1.406 0.99
102_K 108_K 1.396 0.99
28_A 204_R 1.379 0.99
25_L 206_V 1.371 0.99
181_H 186_T 1.348 0.99
221_T 225_Q 1.343 0.99
6_L 46_T 1.341 0.99
117_W 120_Q 1.34 0.99
162_L 177_I 1.338 0.99
67_R 70_D 1.338 0.99
60_D 69_N 1.337 0.99
287_D 347_K 1.336 0.99
79_A 151_R 1.332 0.99
178_S 201_M 1.326 0.99
245_G 279_I 1.316 0.99
56_I 61_L 1.313 0.99
305_A 314_L 1.311 0.99
5_S 65_G 1.309 0.99
12_I 58_G 1.308 0.99
220_K 224_N 1.303 0.99
56_I 69_N 1.296 0.99
181_H 188_M 1.293 0.99
209_K 230_F 1.277 0.99
116_N 120_Q 1.26 0.99
32_F 181_H 1.259 0.99
289_H 342_H 1.252 0.99
25_L 216_V 1.247 0.99
116_N 125_R 1.244 0.98
108_K 112_D 1.233 0.98
152_E 183_K 1.229 0.98
20_V 23_F 1.228 0.98
162_L 190_Y 1.217 0.98
238_P 282_G 1.215 0.98
99_F 103_M 1.212 0.98
35_F 206_V 1.209 0.98
32_F 201_M 1.185 0.98
79_A 188_M 1.169 0.97
244_R 280_V 1.166 0.97
302_I 314_L 1.152 0.97
9_I 56_I 1.15 0.97
8_H 58_G 1.149 0.97
204_R 216_V 1.147 0.97
224_N 307_L 1.146 0.97
10_Q 21_K 1.14 0.97
12_I 19_V 1.136 0.97
9_I 49_M 1.131 0.97
225_Q 349_H 1.117 0.96
195_Q 234_F 1.113 0.96
85_Y 164_N 1.111 0.96
71_V 75_A 1.103 0.96
29_D 64_D 1.102 0.96
168_K 233_G 1.1 0.96
253_V 258_K 1.094 0.96
288_I 343_F 1.092 0.96
217_G 222_V 1.09 0.96
123_G 176_E 1.09 0.96
117_W 183_K 1.089 0.96
97_M 118_A 1.08 0.95
215_Q 231_V 1.08 0.95
119_A 124_L 1.075 0.95
317_T 320_G 1.074 0.95
344_D 347_K 1.069 0.95
61_L 68_M 1.066 0.95
352_D 355_T 1.056 0.95
41_C 46_T 1.053 0.95
283_I 288_I 1.052 0.95
95_D 98_A 1.05 0.94
32_F 188_M 1.047 0.94
88_Y 151_R 1.035 0.94
300_A 339_I 1.035 0.94
9_I 61_L 1.032 0.94
46_T 208_M 1.027 0.94
248_D 253_V 1.022 0.93
207_I 222_V 1.021 0.93
178_S 182_Q 1.021 0.93
158_M 190_Y 1.021 0.93
300_A 318_V 1.02 0.93
97_M 115_V 1.01 0.93
240_M 282_G 1.005 0.93
316_T 325_V 1.001 0.92
167_A 174_R 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2it1A20.99171000.154Contact Map0.855
1v43A10.99171000.157Contact Map0.836
1g29120.99721000.172Contact Map0.868
2yyzA10.97781000.175Contact Map0.772
1oxxK10.94441000.178Contact Map0.722
3rlfA20.98331000.181Contact Map0.81
3fvqA20.96941000.2Contact Map0.747
3d31A20.92781000.21Contact Map0.729
1z47A20.94441000.223Contact Map0.832
3gd7A40.951000.281Contact Map0.698

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0271 seconds.