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ARNC - Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase
UniProt: P77757 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14090
Length: 322 (308)
Sequences: 2696
Seq/Len: 8.75

ARNC
Paralog alert: 0.39 [within 20: 0.03] - ratio of genomes with paralogs
Cluster includes: ARNC GTRB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
47_D 73_L 4.899 1.00
20_Q 53_N 4.838 1.00
58_L 71_S 3.934 1.00
116_K 119_E 3.651 1.00
121_Y 196_I 3.532 1.00
53_N 56_H 3.425 1.00
59_V 312_Q 3.414 1.00
29_R 108_E 2.939 1.00
168_R 172_D 2.823 1.00
247_G 279_T 2.647 1.00
55_A 71_S 2.55 1.00
16_V 54_S 2.537 1.00
11_S 93_G 2.525 1.00
116_K 196_I 2.475 1.00
27_I 66_N 2.432 1.00
25_E 28_R 2.364 1.00
112_R 115_A 2.323 1.00
55_A 73_L 2.303 1.00
27_I 61_A 2.29 1.00
105_N 202_H 2.219 1.00
11_S 42_E 2.219 1.00
95_L 117_A 2.145 1.00
127_V 199_P 2.134 1.00
45_L 58_L 2.071 1.00
73_L 311_Q 2.07 1.00
115_A 118_D 2.048 1.00
129_Q 201_H 2.04 1.00
27_I 45_L 2.033 1.00
122_D 167_R 1.997 1.00
97_I 110_I 1.981 1.00
288_M 291_L 1.98 1.00
117_A 167_R 1.96 1.00
96_I 171_V 1.958 1.00
295_I 298_I 1.932 1.00
240_G 282_G 1.896 1.00
14_I 26_L 1.896 1.00
24_P 57_M 1.87 1.00
27_I 69_I 1.847 1.00
95_L 165_A 1.813 1.00
42_E 93_G 1.795 1.00
53_N 57_M 1.789 1.00
11_S 44_L 1.756 1.00
89_S 175_L 1.689 1.00
24_P 60_E 1.683 1.00
97_I 165_A 1.677 1.00
74_L 86_A 1.642 1.00
18_N 51_S 1.638 1.00
234_R 293_E 1.629 1.00
24_P 28_R 1.623 1.00
25_E 29_R 1.611 1.00
29_R 203_A 1.608 1.00
254_L 271_F 1.569 1.00
117_A 165_A 1.558 1.00
173_A 193_R 1.545 1.00
57_M 60_E 1.531 1.00
14_I 101_A 1.525 1.00
113_L 126_T 1.512 1.00
116_K 121_Y 1.501 1.00
72_I 310_V 1.493 1.00
236_L 287_G 1.474 1.00
115_A 119_E 1.463 1.00
125_G 197_E 1.461 1.00
9_K 94_D 1.454 0.99
80_Q 212_Y 1.451 0.99
56_H 60_E 1.45 0.99
23_L 57_M 1.44 0.99
25_E 206_E 1.42 0.99
167_R 170_I 1.415 0.99
41_Y 68_H 1.414 0.99
17_Y 51_S 1.411 0.99
129_Q 199_P 1.397 0.99
205_R 208_G 1.388 0.99
89_S 308_Y 1.386 0.99
57_M 61_A 1.353 0.99
173_A 309_F 1.348 0.99
17_Y 77_N 1.342 0.99
16_V 45_L 1.322 0.99
28_R 32_T 1.316 0.99
251_A 275_A 1.313 0.99
170_I 191_F 1.312 0.99
95_L 114_V 1.311 0.99
31_T 66_N 1.308 0.99
34_C 41_Y 1.307 0.99
60_E 64_A 1.305 0.99
245_I 249_S 1.287 0.98
13_V 96_I 1.279 0.98
109_E 112_R 1.278 0.98
82_S 307_R 1.276 0.98
22_S 206_E 1.276 0.98
39_K 118_D 1.265 0.98
91_V 96_I 1.252 0.98
70_V 313_V 1.243 0.98
146_R 150_R 1.24 0.98
269_G 272_M 1.239 0.98
149_Q 155_A 1.236 0.98
135_W 139_T 1.233 0.98
173_A 176_H 1.2 0.97
12_V 99_L 1.193 0.97
29_R 32_T 1.193 0.97
255_V 275_A 1.188 0.97
125_G 195_A 1.169 0.97
298_I 302_V 1.169 0.97
13_V 87_G 1.166 0.97
14_I 99_L 1.163 0.97
90_H 313_V 1.161 0.97
29_R 107_P 1.155 0.96
26_L 30_T 1.15 0.96
75_N 309_F 1.149 0.96
43_I 69_I 1.143 0.96
86_A 308_Y 1.136 0.96
13_V 46_I 1.133 0.96
10_V 34_C 1.128 0.96
88_F 98_T 1.123 0.96
180_R 304_A 1.12 0.95
23_L 101_A 1.117 0.95
59_V 73_L 1.11 0.95
116_K 198_I 1.101 0.95
99_L 107_P 1.094 0.95
53_N 60_E 1.092 0.95
166_Y 171_V 1.089 0.94
16_V 101_A 1.087 0.94
106_P 109_E 1.086 0.94
17_Y 47_D 1.086 0.94
81_H 185_P 1.084 0.94
27_I 31_T 1.08 0.94
81_H 217_L 1.076 0.94
31_T 41_Y 1.075 0.94
172_D 175_L 1.075 0.94
137_R 140_A 1.073 0.94
84_I 98_T 1.072 0.94
85_M 307_R 1.066 0.94
253_L 257_L 1.061 0.93
183_F 220_L 1.06 0.93
72_I 90_H 1.055 0.93
12_V 34_C 1.055 0.93
73_L 312_Q 1.046 0.93
80_Q 217_L 1.046 0.93
139_T 143_M 1.033 0.92
248_F 252_V 1.032 0.92
88_F 171_V 1.031 0.92
47_D 55_A 1.03 0.92
196_I 199_P 1.027 0.92
80_Q 185_P 1.026 0.92
70_V 92_T 1.018 0.91
277_L 284_Q 1.016 0.91
55_A 59_V 1.015 0.91
45_L 69_I 1.014 0.91
105_N 161_C 1.007 0.91
88_F 175_L 1.006 0.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2bo4A60.87581000.676Contact Map0.518
2wvlA20.78261000.683Contact Map0.565
2zu9A20.7951000.686Contact Map0.526
3ckjA10.816899.90.706Contact Map0.598
3f1yA20.869699.90.71Contact Map0.571
2z86A40.757899.90.727Contact Map0.774
2d7iA10.975299.90.733Contact Map0.594
3bcvA20.658499.90.736Contact Map0.784
4fixA20.968999.90.751Contact Map0.645
1qg8A10.698899.90.752Contact Map0.754

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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