GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Secretin - Bacterial type II and III secretion system protein
Pfam: PF00263 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 165
Sequences: 2231
Seq/Len: 13.52
HH_delta: 0.003 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
129_G134_G1.164245.389
141_Y144_G0.943654.368
23_P62_E0.795763.684
129_G135_D0.682773.161
112_T160_T0.634822.939
31_E56_D0.623492.886
78_D102_S0.549222.542
31_E55_I0.500482.317
136_I139_L0.495782.295
108_R111_E0.484312.242
23_P64_T0.466852.161
33_P54_Y0.459592.127
141_Y146_K0.453782.101
112_T158_F0.451262.089
125_N148_K0.420711.947
80_E100_S0.404351.872
72_R108_R0.403691.869
83_S97_S0.38111.764
76_E104_T0.376641.743
121_D150_K0.370551.715
27_S56_D0.370151.713
107_V113_V0.363021.680
122_Q151_E0.359291.663
121_D152_K0.355031.643
20_N67_I0.347961.611
114_V158_F0.331671.535
78_D100_S0.327711.517
33_P52_V0.32431.501
72_R106_R0.322941.495
30_Q97_S0.310621.438
22_Q104_T0.306081.417
34_Y54_Y0.303711.406
109_D162_R0.302311.399
127_E144_G0.301081.394
77_I159_I0.300131.389
132_F136_I0.300081.389
140_G144_G0.299481.386
18_T24_A0.298181.380
83_S122_Q0.29731.376
107_V161_P0.293291.358
56_D98_T0.290741.346
9_K152_K0.289391.340
76_E102_S0.289291.339
21_G66_R0.288191.334
31_E98_T0.286681.327
25_T62_E0.283871.314
60_S80_E0.283121.311
123_N150_K0.278821.291
105_V113_V0.273241.265
36_S53_E0.273061.264
101_I116_G0.269771.249
58_G82_S0.265681.230
101_I115_I0.264281.223
18_T65_P0.261681.211
30_Q85_V0.260521.206
132_F135_D0.258331.196
85_V97_S0.257731.193
31_E96_I0.256151.186
133_L143_F0.255021.180
16_I101_I0.2461.139
74_T104_T0.245091.135
138_L141_Y0.242811.124
27_S100_S0.241631.119
28_V118_L0.240331.112
57_V96_I0.239131.107
84_L94_P0.233271.080
27_S60_S0.232981.078
14_P24_A0.232561.077
125_N146_K0.232541.076
59_L81_I0.231731.073
62_E78_D0.230831.069
25_T102_S0.228841.059
35_I52_V0.225191.042
129_G144_G0.221451.025
86_S95_Q0.221331.025
119_I152_K0.220891.022
127_E146_K0.216561.002
83_S120_Q0.216491.002
33_P55_I0.215750.999
32_I84_L0.215370.997
68_L74_T0.205550.951
35_I91_V0.204520.947
135_D144_G0.203470.942
134_G144_G0.203150.940
123_N148_K0.202050.935
4_Q128_S0.200180.927
84_L96_I0.199660.924
32_I96_I0.199270.922
30_Q57_V0.197180.913
55_I96_I0.196790.911
131_P143_F0.195270.904
31_E54_Y0.194590.901
56_D60_S0.192670.892
19_L22_Q0.191160.885
81_I99_R0.190980.884
36_S52_V0.190570.882
57_V84_L0.189520.877
14_P117_G0.187730.869
126_S147_S0.184550.854
26_I116_G0.183040.847
3_E10_I0.18210.843
33_P95_Q0.181410.840
141_Y149_S0.180660.836
19_L74_T0.180130.834
3_E135_D0.179080.829
136_I143_F0.179030.829
34_Y94_P0.179020.829
36_S51_S0.1790.829
85_V95_Q0.178910.828
25_T60_S0.177850.823
85_V88_S0.177740.823
99_R120_Q0.177470.822
35_I93_L0.177460.821
120_Q153_T0.17720.820
37_S51_S0.177110.820
34_Y96_I0.176950.819
58_G81_I0.173560.803
18_T64_T0.171820.795
35_I50_T0.171740.795
59_L101_I0.171140.792
130_V133_L0.164140.760
137_P143_F0.163460.757
28_V99_R0.162930.754
89_S92_Q0.162610.753
38_S50_T0.162010.750
71_G163_I0.161390.747
64_T76_E0.161290.747
37_S49_S0.160320.742
18_T59_L0.159350.738
16_I115_I0.157660.730
79_P157_I0.15760.730
30_Q95_Q0.15710.727
145_S148_K0.155770.721
39_E53_E0.155760.721
148_K151_E0.155710.721
16_I82_S0.154520.715
145_S149_S0.154030.713
128_S147_S0.153740.712
20_N66_R0.153640.711
34_Y80_E0.153440.710
129_G132_F0.151840.703
73_V107_V0.151720.702
126_S149_S0.151650.702
17_T105_V0.15140.701
126_S132_F0.150980.699
40_T50_T0.150670.697
127_E133_L0.150210.695
15_S161_P0.149380.691
25_T100_S0.148930.689
101_I157_I0.147960.685
28_V59_L0.14790.685
92_Q95_Q0.146740.679
22_Q111_E0.146550.678
71_G108_R0.145920.675
74_T106_R0.144850.671
16_I24_A0.144160.667
124_S149_S0.14230.659
67_I163_I0.141760.656
122_Q153_T0.140260.649
133_L136_I0.139870.647
112_T159_I0.139810.647
58_G158_F0.138980.643
37_S52_V0.138460.641
132_F138_L0.13820.640
75_L107_V0.136930.634
16_I68_L0.136480.632
27_S157_I0.136110.630
29_G77_I0.13610.630
59_L79_P0.136080.630
73_V163_I0.136030.630
122_Q163_I0.135640.628
14_P103_T0.134960.625
59_L119_I0.134630.623
68_L106_R0.134610.623
101_I113_V0.133780.619
18_T114_V0.133310.617
63_V116_G0.132810.615
58_G118_L0.132620.614
38_S49_S0.132340.613
89_S122_Q0.132270.612
59_L118_L0.131910.611
130_V144_G0.131660.609
6_G126_S0.131620.609
79_P118_L0.131390.608
113_V161_P0.130590.605
6_G73_V0.130470.604
28_V81_I0.13040.604
87_N92_Q0.130240.603
140_G143_F0.129750.601
150_K163_I0.129660.600
63_V75_L0.129380.599
39_E49_S0.128910.597
20_N106_R0.128680.596
80_E98_T0.128090.593
11_L119_I0.127660.591
99_R155_L0.127430.590
54_Y93_L0.127230.589
155_L158_F0.126490.586
127_E134_G0.126170.584
30_Q84_L0.12590.583
16_I26_I0.125810.582
16_I25_T0.125540.581
99_R118_L0.125530.581
54_Y96_I0.125410.581
128_S145_S0.125390.580
131_P137_P0.124770.578
77_I113_V0.124740.577
27_S58_G0.124520.576
72_R79_P0.124480.576
126_S145_S0.124270.575
23_P89_S0.124160.575
10_I14_P0.124050.574
15_S153_T0.123910.574
9_K121_D0.12390.574
21_G140_G0.123620.572
123_N146_K0.123590.572
30_Q96_I0.123330.571
34_Y53_E0.123260.571
12_S116_G0.123220.570
37_S54_Y0.122870.569
2_L5_Q0.12260.568
126_S146_K0.122260.566
126_S150_K0.122250.566
108_R128_S0.122150.565
73_V161_P0.122110.565
72_R123_N0.121970.565
12_S29_G0.121840.564
1_A109_D0.121480.562
15_S68_L0.121380.562
2_L8_A0.121370.562
87_N95_Q0.121310.562
71_G109_D0.12130.561
145_S151_E0.121240.561
12_S157_I0.121020.560
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4av2A0.97581000.003
3cdiA0.51527.60.941
3ixqA0.70913.60.949
3u1kA0.52122.90.951
3bfvA0.36972.90.951
3mb5A0.33942.20.954
3gmeA0.51522.10.954
2kuqA0.30912.10.955
1b35D0.32121.70.957
3j26A0.51521.50.958

Page generated in 0.0245 seconds.