GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
AsnC_trans_reg - AsnC family
Pfam: PF01037 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0032
Length: 74
Sequences: 6101
Seq/Len: 82.45
HH_delta: -0.015 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
27_E40_K1.701322.956
34_E67_E1.640382.850
4_K65_R1.515312.632
44_R48_E1.340832.329
26_V42_R1.340642.329
6_E64_R1.289052.239
22_I52_F1.132561.967
51_E55_E1.096011.904
48_E51_E1.056381.835
45_D48_E0.989181.718
50_E73_S0.947651.646
16_A20_A0.938121.630
15_F19_L0.925881.608
2_L69_S0.87751.524
3_V39_L0.837681.455
13_D17_E0.802241.394
18_A21_E0.785261.364
9_H14_E0.783661.361
16_A73_S0.770561.339
18_A60_I0.761791.323
25_V41_V0.746511.297
24_E48_E0.746311.296
2_L35_Y0.722761.256
31_V38_I0.704381.224
2_L67_E0.668461.161
4_K64_R0.663991.153
28_C39_L0.661731.150
14_E18_A0.655841.139
29_Y40_K0.638081.108
50_E54_R0.625961.087
29_Y71_V0.610951.061
43_A52_F0.60631.053
16_A37_L0.596531.036
6_E9_H0.592451.029
46_M72_L0.589761.025
17_E20_A0.584731.016
5_V15_F0.571220.992
4_K34_E0.566290.984
41_V52_F0.554370.963
43_A48_E0.544190.945
32_T72_L0.516280.897
3_V63_V0.507250.881
30_S58_R0.502430.873
32_T70_I0.502360.873
12_Y37_L0.502030.872
31_V69_S0.495910.861
30_S54_R0.495880.861
17_E21_E0.48540.843
46_M70_I0.482520.838
26_V40_K0.474890.825
15_F37_L0.473540.823
49_L70_I0.456580.793
54_R58_R0.453270.787
47_E50_E0.450830.783
18_A22_I0.449760.781
30_S73_S0.449650.781
30_S50_E0.446060.775
2_L34_E0.445870.775
30_S37_L0.445370.774
2_L38_I0.443090.770
25_V39_L0.437950.761
28_C36_D0.426810.741
12_Y58_R0.425270.739
6_E62_G0.425070.738
35_Y67_E0.420740.731
22_I60_I0.415260.721
18_A59_S0.408170.709
30_S72_L0.404790.703
53_I66_T0.404740.703
20_A28_C0.399670.694
13_D54_R0.399530.694
28_C37_L0.395730.687
3_V66_T0.395710.687
14_E61_P0.395070.686
53_I72_L0.374690.651
24_E43_A0.374290.650
58_R66_T0.372950.648
9_H61_P0.368810.641
13_D16_A0.367540.638
48_E52_F0.365630.635
35_Y69_S0.360830.627
30_S36_D0.359010.624
22_I55_E0.358220.622
47_E51_E0.35690.620
54_R72_L0.351940.611
52_F57_L0.350930.610
49_L68_T0.35080.609
41_V49_L0.350640.609
31_V71_V0.350040.608
14_E62_G0.34620.601
24_E44_R0.345140.600
20_A73_S0.342890.596
58_R65_R0.340690.592
50_E53_I0.340210.591
19_L28_C0.339860.590
19_L22_I0.339620.590
18_A62_G0.335820.583
25_V28_C0.332080.577
53_I57_L0.331350.576
24_E52_F0.331290.576
49_L53_I0.330030.573
47_E73_S0.329760.573
14_E17_E0.32760.569
19_L39_L0.32460.564
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
Top (length/2) GREMLIN results overlayed on top 10 PDB hits:

Legend: The grey circles underneath are pdb residue contacts (min distance < 5 Angstroms). The coloring of these circles is based on HHsearch results which uses the overall probability, per-site alignment prob and agreement of top hits weighted by HHsearch score (Note we only consider monomeric contacts, there might be homo-oligomeric contacts in the pdb that are not shown.)
PDB Cov Prob HH_delta
2cviA0.97399.4-0.015
2djwA0.97399.3-0.004
2zbcA0.97399.30.009
2dbbA0.97399.20.063
2cg4A0.986599.20.068
2e1cA0.959599.20.071
2cyyA0.959599.20.08
2p5vA199.20.087
3i4pA0.986599.10.093
1i1gA0.97399.10.115

Page generated in 0.011 seconds.