GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
CDP-OH_P_transf - CDP-alcohol phosphatidyltransferase
Pfam: PF01066 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 101
Sequences: 1495
Seq/Len: 14.8
HH_delta: 0.911 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
10_L63_L0.85323.665
39_A71_S0.503082.161
24_L82_A0.480772.065
27_R30_L0.448381.926
43_D64_D0.42981.846
41_L45_L0.427071.835
13_L67_A0.409531.759
58_P62_Y0.395211.698
23_L82_A0.391431.681
12_R42_L0.380661.635
15_L35_L0.371451.596
27_R31_L0.369151.586
8_I49_L0.332361.428
34_L38_L0.324161.392
4_T7_A0.31921.371
15_L42_L0.310841.335
65_S72_F0.307051.319
61_A69_R0.306751.318
30_L34_L0.304841.309
12_R71_S0.297831.279
48_W52_R0.296691.274
43_D51_R0.285911.228
22_L82_A0.282581.214
18_L37_F0.278091.195
51_R64_D0.27251.171
70_I74_A0.266671.146
25_Q31_L0.262961.130
19_A75_L0.259861.116
22_L31_L0.254181.092
45_L48_W0.251831.082
18_L22_L0.249281.071
28_P36_L0.247261.062
23_L32_A0.24531.054
14_L21_L0.24421.049
35_L38_L0.244031.048
58_P61_A0.242171.040
53_R63_L0.227630.978
73_V76_P0.225430.968
18_L35_L0.223610.961
20_A75_L0.222840.957
69_R72_F0.221790.953
7_A11_L0.21940.942
39_A72_F0.214240.920
31_L34_L0.214180.920
22_L35_L0.214090.920
6_N57_S0.212860.914
15_L38_L0.209290.899
10_L14_L0.208880.897
26_G31_L0.208840.897
12_R61_A0.206890.889
72_F76_P0.205830.884
40_F44_G0.204930.880
5_P49_L0.204780.880
6_N53_R0.202060.868
8_I11_L0.198310.852
23_L75_L0.195910.842
18_L21_L0.19580.841
12_R44_G0.195420.839
37_F40_F0.194650.836
67_A72_F0.193410.831
16_G32_A0.192120.825
72_F75_L0.191690.823
31_L82_A0.189960.816
16_G76_P0.18910.812
10_L27_R0.188650.810
42_L45_L0.187880.807
17_F28_P0.187410.805
35_L58_P0.187230.804
4_T49_L0.186980.803
39_A65_S0.184770.794
43_D46_D0.183710.789
12_R67_A0.183680.789
21_L82_A0.183520.788
9_T39_A0.183320.787
38_L42_L0.181520.780
8_I48_W0.18130.779
4_T53_R0.180990.777
14_L30_L0.18060.776
65_S73_V0.180.773
11_L15_L0.17880.768
62_Y66_V0.178380.766
9_T67_A0.178160.765
4_T8_I0.177940.764
6_N63_L0.177250.761
35_L56_S0.174880.751
14_L17_F0.173930.747
16_G72_F0.172330.740
32_A81_L0.171770.738
19_A36_L0.171180.735
23_L45_L0.169170.727
21_L25_Q0.168430.724
66_V70_I0.167430.719
18_L27_R0.166380.715
21_L31_L0.165670.712
43_D65_S0.162440.698
25_Q81_L0.162150.697
65_S68_D0.161630.694
74_A81_L0.161590.694
19_A32_A0.161570.694
37_F52_R0.161180.692
62_Y65_S0.16080.691
5_P8_I0.160690.690
41_L49_L0.160160.688
23_L26_G0.158760.682
24_L30_L0.158740.682
32_A72_F0.158330.680
14_L53_R0.158270.680
16_G39_A0.157160.675
46_D64_D0.156790.674
30_L33_A0.156480.672
21_L74_A0.155290.667
11_L31_L0.155230.667
7_A57_S0.155090.666
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3h90A0.81195.30.911
3j1zP0.81195.30.911
2z34C0.12872.70.922
3j08A0.59411.50.931
3j09A0.59411.40.933
2y4xA0.30691.20.935
3r4dB0.91091.10.936
4hytB0.46531.10.937
1wlxA0.41581.10.937
4av3A0.752510.937
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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