GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
FTSW_RODA_SPOVE - Cell cycle protein
Pfam: PF01098 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0142
Length: 358
Sequences: 3839
Seq/Len: 10.72
HH_delta: 0.976 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
284_L304_A0.70463.824
284_L349_L0.614253.333
300_A349_L0.581573.156
96_R99_G0.534272.899
59_Y296_G0.50562.744
214_D217_G0.487222.644
166_V305_M0.460692.500
262_G270_G0.454462.466
229_I262_G0.452362.455
6_L279_L0.444422.412
11_S44_L0.435342.362
210_N213_K0.419622.277
303_I349_L0.418242.270
251_E254_T0.416552.260
6_L280_L0.415842.257
47_G343_M0.412822.240
87_E92_R0.403832.191
73_S111_L0.401412.178
32_N38_I0.394682.142
54_F344_I0.391772.126
7_V346_I0.386462.097
316_G322_L0.374182.030
239_L265_F0.369522.005
296_G352_I0.361961.964
73_S108_A0.361631.962
79_L84_F0.359661.952
261_I273_V0.358481.945
167_M302_G0.358291.944
331_F342_N0.358291.944
317_M324_V0.358071.943
114_L299_L0.357211.938
159_I327_I0.356811.936
331_F346_I0.355591.930
170_V301_I0.354341.923
258_F270_G0.350581.902
17_M261_I0.343741.865
130_N133_G0.341931.855
69_L111_L0.341651.854
51_M350_L0.340551.848
71_L75_I0.333721.811
311_A315_I0.328421.782
274_L315_I0.327341.776
224_Q244_Q0.325391.766
15_L37_F0.322341.749
17_M265_F0.317861.725
145_V157_A0.316541.718
271_I275_L0.316431.717
113_I302_G0.312911.698
146_F150_L0.310531.685
63_K295_F0.308521.674
235_F268_I0.306191.662
284_L300_A0.303181.645
242_G260_V0.302941.644
281_I308_F0.302921.644
93_R105_S0.302391.641
105_S156_T0.293341.592
212_E223_I0.291561.582
227_I244_Q0.289871.573
258_F315_I0.289251.570
163_I306_L0.283011.536
222_L324_V0.276691.501
13_I261_I0.276681.501
300_A352_I0.276091.498
112_L160_L0.275191.493
89_N251_E0.274981.492
41_L45_I0.274111.487
291_A352_I0.27281.480
261_I332_I0.272281.478
20_S264_E0.271321.472
10_L332_I0.270081.466
96_R101_S0.261691.420
59_Y351_S0.261391.418
78_L82_F0.259531.408
15_L41_L0.257751.399
141_I164_F0.25771.398
21_A260_V0.257691.398
65_Y68_I0.257611.398
267_W271_I0.255461.386
351_S355_R0.255091.384
50_V344_I0.254521.381
167_M298_L0.254191.379
10_L273_V0.252451.370
349_L352_I0.252271.369
225_A318_N0.252211.369
328_T338_S0.251671.366
102_I107_F0.251241.363
55_S347_G0.248781.350
3_L280_L0.246681.339
237_K243_Q0.246581.338
13_I273_V0.245511.332
75_I79_L0.244541.327
286_R290_R0.244311.326
80_V104_P0.243671.322
13_I276_L0.243481.321
6_L276_L0.243441.321
113_I163_I0.242091.314
43_F336_G0.241691.312
35_S39_K0.241491.310
256_F324_V0.241281.309
281_I304_A0.241241.309
299_L352_I0.238231.293
62_L348_L0.238141.292
17_M257_I0.237731.290
242_G264_E0.236851.285
55_S351_S0.234741.274
59_Y293_D0.233731.268
304_A349_L0.232451.261
257_I261_I0.229911.248
234_L268_I0.229791.247
281_I311_A0.229561.246
174_P177_Y0.22821.238
198_K201_Q0.227321.234
156_T328_T0.226271.228
77_L80_V0.226171.227
234_L267_W0.225061.221
254_T334_Y0.224831.220
80_V95_I0.224821.220
15_L40_Q0.224811.220
11_S343_M0.224311.217
77_L108_A0.223571.213
303_I345_L0.223511.213
106_E109_K0.223241.211
120_L167_M0.222761.209
45_I49_I0.221111.200
68_I72_G0.22061.197
203_E218_A0.220111.194
225_A259_A0.218791.187
274_L311_A0.218581.186
293_D296_G0.218561.186
79_L95_I0.216941.177
86_T96_R0.215521.170
51_M347_G0.214941.166
155_G325_T0.213931.161
59_Y352_I0.213721.160
7_V343_M0.213711.160
215_P223_I0.213351.158
116_L164_F0.21271.154
117_A167_M0.212061.151
277_F311_A0.211691.149
329_L332_I0.211391.147
44_L339_L0.209921.139
306_L345_L0.208351.131
35_S38_I0.208011.129
112_L141_I0.206991.123
214_D219_G0.206751.122
222_L320_G0.206751.122
162_A309_V0.205681.116
249_L259_A0.205261.114
50_V340_L0.204691.111
287_I300_A0.204111.108
3_L287_I0.203711.105
310_Q328_T0.203471.104
315_I319_L0.203361.104
211_P219_G0.203311.103
231_S237_K0.202981.101
49_I53_I0.202641.100
212_E226_L0.202361.098
142_F146_F0.201551.094
288_A300_A0.201041.091
199_P202_L0.200951.090
155_G317_M0.200561.088
207_A218_A0.199921.085
74_L78_L0.197321.071
36_F253_H0.197271.070
225_A256_F0.197241.070
61_K65_Y0.195741.062
16_L239_L0.195621.062
57_I62_L0.194681.056
118_G122_K0.194631.056
270_G319_L0.193761.051
113_I167_M0.193631.051
348_L352_I0.193511.050
79_L82_F0.193411.050
48_F52_F0.192781.046
199_P203_E0.192551.045
219_G223_I0.192061.042
107_F341_I0.192061.042
19_Y37_F0.191341.038
40_Q43_F0.19121.038
38_I41_L0.191191.037
67_K71_L0.189911.031
214_D218_A0.189571.029
66_S295_F0.188971.025
273_V332_I0.188961.025
178_I182_I0.188361.022
81_L150_L0.188211.021
170_V305_M0.18691.014
93_R155_G0.186041.010
224_Q227_I0.185471.006
36_F334_Y0.183940.998
149_L157_A0.183520.996
310_Q338_S0.183420.995
307_I342_N0.182310.989
190_L193_I0.18140.984
53_I57_I0.179910.976
347_G351_S0.17920.972
221_Q225_A0.178680.970
273_V276_L0.177160.961
88_V101_S0.177090.961
220_Y224_Q0.176420.957
63_K121_S0.176250.956
114_L295_F0.176210.956
47_G347_G0.17620.956
139_L143_I0.174720.948
288_A301_I0.174050.944
38_I42_I0.173680.942
315_I329_L0.173170.940
133_G136_I0.172920.938
317_M325_T0.172830.938
37_F41_L0.171940.933
350_L353_Y0.171060.928
227_I230_A0.170950.928
163_I166_V0.170720.926
61_K64_K0.169730.921
317_M322_L0.169660.921
282_F286_R0.169610.920
154_L158_L0.16950.920
59_Y299_L0.169470.920
283_R350_L0.168520.914
211_P223_I0.168230.913
110_I345_L0.168120.912
202_L206_Q0.167320.908
110_I341_I0.167140.907
67_K115_F0.16710.907
46_L340_L0.166250.902
47_G339_L0.166070.901
161_F165_L0.165320.897
48_F51_M0.165270.897
203_E206_Q0.165030.896
47_G340_L0.164110.891
252_A260_V0.163810.889
261_I265_F0.163530.887
226_L320_G0.16310.885
93_R152_P0.1630.885
12_L16_L0.162830.884
280_L346_I0.162420.881
312_L322_L0.162380.881
18_I21_A0.161940.879
224_Q250_P0.161370.876
46_L49_I0.161260.875
337_S341_I0.161060.874
8_L12_L0.159520.866
51_M346_I0.159080.863
277_F331_F0.158270.859
260_V264_E0.1580.857
93_R325_T0.157910.857
86_T101_S0.157830.856
296_G299_L0.157330.854
278_L282_F0.155910.846
2_L279_L0.155690.845
222_L256_F0.155330.843
273_V277_F0.154850.840
158_L162_A0.154450.838
13_I17_M0.154290.837
135_L139_L0.154060.836
155_G254_T0.153610.834
148_I160_L0.153380.832
307_I311_A0.153070.831
107_F344_I0.152850.829
342_N345_L0.152790.829
102_I337_S0.151890.824
180_L183_L0.151030.820
258_F329_L0.150880.819
68_I71_L0.150190.815
51_M54_F0.150050.814
39_K334_Y0.149630.812
114_L118_G0.148950.808
18_I257_I0.148920.808
66_S118_G0.148920.808
42_I45_I0.148910.808
32_N35_S0.148850.808
60_R293_D0.148520.806
222_L225_A0.148430.805
96_R100_F0.147530.801
39_K42_I0.147450.800
267_W270_G0.147060.798
78_L81_L0.146870.797
179_L183_L0.14660.796
285_F304_A0.146490.795
284_L287_I0.146440.795
50_V53_I0.146320.794
19_Y34_F0.146280.794
220_Y250_P0.146250.794
75_I82_F0.146180.793
238_G264_E0.145960.792
113_I306_L0.145870.792
153_D156_T0.14530.788
91_A152_P0.144210.783
295_F299_L0.144120.782
120_L168_L0.14410.782
280_L307_I0.143960.781
91_A151_Q0.143270.777
169_F175_K0.143080.776
207_A222_L0.143080.776
249_L252_A0.1420.771
80_V92_R0.141890.770
196_F199_P0.141760.769
107_F337_S0.141460.768
154_L201_Q0.140880.764
89_N253_H0.140820.764
80_V85_G0.140660.763
197_L201_Q0.140440.762
78_L147_L0.140270.761
120_L171_S0.139560.757
92_R151_Q0.139210.755
40_Q44_L0.138730.753
275_L279_L0.138690.753
299_L348_L0.138670.752
34_F37_F0.138290.750
224_Q230_A0.13820.750
287_I353_Y0.138190.750
245_K264_E0.138180.750
77_L147_L0.138080.749
70_Y144_P0.137640.747
62_L299_L0.137550.746
86_T92_R0.13740.746
47_G50_V0.137010.743
9_L276_L0.136750.742
74_L143_I0.136630.741
208_F319_L0.136090.738
10_L14_G0.136060.738
189_I193_I0.136030.738
285_F305_M0.135540.736
70_Y115_F0.13550.735
232_G263_E0.135240.734
93_R151_Q0.135130.733
65_Y69_L0.134740.731
145_V161_F0.134460.730
187_G191_I0.134430.729
14_G17_M0.134240.728
108_A151_Q0.134010.727
67_K118_G0.133920.727
43_F47_G0.133580.725
63_K118_G0.133540.725
175_K179_L0.133430.724
117_A121_S0.133060.722
303_I346_I0.132710.720
287_I349_L0.132680.720
66_S111_L0.132460.719
55_S350_L0.131630.714
353_Y356_Q0.131560.714
85_G92_R0.130940.711
253_H334_Y0.130810.710
6_L275_L0.130510.708
203_E207_A0.130360.707
72_G75_I0.130310.707
51_M55_S0.130190.706
270_G274_L0.129840.705
192_V196_F0.129520.703
108_A144_P0.129320.702
58_D296_G0.129310.702
162_A166_V0.129270.701
101_S334_Y0.128940.700
46_L50_V0.12850.697
2_L283_R0.128360.697
118_G295_F0.128240.696
308_F311_A0.128010.695
207_A213_K0.127580.692
320_G324_V0.127390.691
258_F273_V0.127240.690
351_S354_R0.127180.690
210_N219_G0.126950.689
257_I332_I0.126930.689
110_I344_I0.126760.688
40_Q337_S0.126560.687
242_G245_K0.126460.686
301_I305_M0.126360.686
228_A263_E0.126190.685
5_F9_L0.126010.684
225_A319_L0.1260.684
108_A111_L0.125690.682
279_L283_R0.125660.682
214_D223_I0.125540.681
160_L164_F0.125130.679
147_L152_P0.12510.679
60_R291_A0.124890.678
287_I291_A0.124150.674
303_I352_I0.124080.673
72_G79_L0.123970.673
310_Q330_P0.123940.673
43_F337_S0.123850.672
54_F62_L0.123780.672
43_F340_L0.123410.670
183_L189_I0.123360.669
131_W135_L0.123330.669
186_I190_L0.123120.668
165_L169_F0.123080.668
76_L80_V0.122960.667
19_Y240_G0.122650.666
77_L152_P0.122630.665
58_D61_K0.122630.665
43_F331_F0.122360.664
331_F343_M0.121550.660
73_S107_F0.121190.658
93_R156_T0.121170.658
72_G179_L0.121150.657
340_L343_M0.121090.657
55_S354_R0.12070.655
107_F340_L0.120480.654
272_L276_L0.119850.650
256_F318_N0.119810.650
314_N318_N0.119790.650
165_L168_L0.119280.647
288_A304_A0.119260.647
163_I309_V0.118860.645
80_V152_P0.118820.645
18_I40_Q0.118790.645
224_Q248_Y0.118430.643
117_A298_L0.118310.642
230_A251_E0.118080.641
290_R353_Y0.118060.641
240_G264_E0.118030.640
70_Y140_I0.117830.639
142_F182_I0.117620.638
102_I341_I0.11760.638
116_L137_L0.117430.637
152_P200_Y0.117330.637
93_R160_L0.117010.635
210_N223_I0.116980.635
7_V331_F0.116880.634
97_L101_S0.116760.634
112_L116_L0.116610.633
166_V306_L0.1160.629
190_L194_F0.115730.628
39_K43_F0.115610.627
291_A307_I0.115220.625
115_F119_I0.114960.624
4_L51_M0.11490.624
310_Q325_T0.114790.623
147_L151_Q0.114590.622
211_P214_D0.114520.621
242_G252_A0.114440.621
148_I156_T0.114120.619
225_A249_L0.114090.619
299_L303_I0.114050.619
189_I192_V0.114040.619
10_L280_L0.11380.618
285_F301_I0.113790.617
113_I299_L0.113770.617
19_Y23_Y0.113210.614
283_R353_Y0.113120.614
97_L100_F0.113070.614
313_I322_L0.113070.614
191_I194_F0.11280.612
47_G344_I0.112780.612
277_F329_L0.112690.612
300_A304_A0.112620.611
207_A211_P0.112560.611
90_G200_Y0.112160.609
285_F289_R0.1120.608
137_L164_F0.111940.607
40_Q339_L0.11180.607
52_F56_F0.111720.606
197_L205_I0.111630.606
163_I303_I0.111440.605
93_R305_M0.111350.604
338_S342_N0.111120.603
40_Q343_M0.110530.600
200_Y203_E0.110230.598
76_L102_I0.110150.598
275_L278_L0.110070.597
339_L352_I0.109850.596
59_Y355_R0.109690.595
44_L343_M0.109680.595
142_F145_V0.10960.595
166_V309_V0.109280.593
152_P201_Q0.109220.593
91_A325_T0.109180.592
288_A291_A0.109160.592
186_I189_I0.109040.592
232_G264_E0.108650.590
215_P219_G0.108610.589
270_G315_I0.108230.587
149_L152_P0.10820.587
207_A219_G0.107950.586
155_G324_V0.107910.586
54_F347_G0.107850.585
173_I205_I0.107810.585
14_G332_I0.107790.585
280_L284_L0.107650.584
229_I319_L0.107440.583
119_I137_L0.107280.582
305_M309_V0.106850.580
103_Q106_E0.106830.580
141_I145_V0.106820.580
151_Q156_T0.106570.578
93_R153_D0.106480.578
238_G242_G0.106450.578
13_I272_L0.106420.577
130_N136_I0.106360.577
70_Y74_L0.106080.576
224_Q242_G0.105740.574
135_L147_L0.105730.574
228_A249_L0.105610.573
341_I345_L0.105540.573
115_F137_L0.105410.572
39_K45_I0.105390.572
7_V280_L0.105320.572
253_H259_A0.105180.571
127_K130_N0.105140.571
205_I316_G0.10510.570
10_L276_L0.105040.570
294_R297_K0.104430.567
242_G263_E0.104350.566
134_L138_L0.10430.566
166_V170_V0.10420.565
195_I328_T0.104150.565
119_I140_I0.104140.565
56_F354_R0.103430.561
148_I157_A0.103270.560
165_L178_I0.103180.560
117_A302_G0.103140.560
296_G351_S0.102910.558
80_V151_Q0.102810.558
237_K241_N0.102710.557
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2k9jB0.117310.40.976
2xndJ0.18448.80.976
4f4sA0.17046.50.978
4j7cI0.52516.10.978
3arcZ0.13975.80.978
4dveA0.33245.40.978
1hgvA0.0953.70.98
1vf5E0.08943.30.98
2kluA0.10063.30.98
4h44G0.08662.80.981
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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