GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
UPF0016 - Uncharacterized protein family UPF0016
Pfam: PF01169 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0292
Length: 78
Sequences: 1384
Seq/Len: 17.74
HH_delta: 0.907 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
71_G75_L0.546142.622
68_W72_A0.410941.973
1_F5_F0.396761.905
65_Y68_W0.358281.720
43_L47_T0.357171.715
12_E15_D0.353391.697
33_W37_A0.348631.674
73_L77_F0.330121.585
65_Y69_V0.327931.574
21_T39_A0.312671.501
2_L6_L0.310681.492
64_R68_W0.303681.458
72_A76_L0.301281.446
48_G52_L0.296011.421
12_E17_T0.290321.394
20_A73_L0.287311.379
14_G18_Q0.274481.318
24_L38_G0.263781.266
24_L34_P0.262161.259
72_A75_L0.253791.218
20_A46_A0.252711.213
51_V55_S0.249941.200
9_F70_A0.242341.164
58_A61_I0.240271.154
39_A43_L0.237451.140
62_P65_Y0.23511.129
9_F71_G0.233851.123
36_F78_G0.233281.120
37_A45_L0.231911.113
16_K74_F0.23081.108
9_F51_V0.22951.102
63_E67_K0.229471.102
40_T53_L0.225041.080
5_F9_F0.224921.080
55_S59_S0.224911.080
8_I46_A0.222331.067
6_L10_L0.213541.025
4_S7_L0.213091.023
16_K19_L0.213021.023
3_T7_L0.212231.019
36_F43_L0.207810.998
57_L60_R0.207290.995
8_I43_L0.205670.987
61_I66_I0.204420.981
13_L17_T0.203980.979
21_T46_A0.203470.977
8_I42_A0.201780.969
46_A50_A0.201430.967
2_L33_W0.20110.966
53_L66_I0.198420.953
37_A41_L0.196480.943
24_L75_L0.19390.931
20_A53_L0.192390.924
39_A65_Y0.192050.922
25_A42_A0.190530.915
25_A73_L0.188380.904
13_L36_F0.184560.886
61_I65_Y0.18320.880
36_F77_F0.181230.870
58_A62_P0.180950.869
28_Y39_A0.180270.865
2_L44_A0.179580.862
10_L54_G0.177670.853
21_T26_A0.174510.838
16_K36_F0.173920.835
2_L41_L0.173640.834
15_D38_G0.171690.824
27_R31_N0.170810.820
64_R71_G0.170580.819
37_A64_R0.16920.812
22_I46_A0.168530.809
2_L59_S0.16650.799
75_L78_G0.165980.797
19_L47_T0.165540.795
49_L66_I0.165410.794
25_A77_F0.165130.793
18_Q46_A0.164480.790
6_L31_N0.162870.782
17_T48_G0.161940.777
34_P76_L0.161820.777
64_R67_K0.161220.774
23_A63_E0.160240.769
8_I12_E0.160080.769
16_K70_A0.158810.762
61_I77_F0.158420.761
53_L62_P0.157070.754
3_T68_W0.157040.754
3_T62_P0.156170.750
17_T67_K0.15610.749
7_L58_A0.156080.749
62_P71_G0.155990.749
8_I40_T0.155390.746
40_T43_L0.155230.745
31_N35_V0.155030.744
43_L46_A0.154710.743
41_L45_L0.154420.741
52_L70_A0.154350.741
52_L57_L0.154180.740
10_L58_A0.154150.740
2_L32_P0.154050.740
11_A47_T0.153820.739
34_P59_S0.153630.738
2_L55_S0.153390.736
11_A19_L0.152470.732
23_A62_P0.152460.732
41_L52_L0.152360.731
12_E50_A0.152190.731
19_L42_A0.151610.728
40_T67_K0.150880.724
42_A51_V0.150830.724
11_A57_L0.15050.723
7_L22_I0.150480.722
56_W72_A0.150440.722
9_F58_A0.150320.722
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4kjrA0.80775.60.907
4kjsA0.80775.60.907
4k1cA0.93593.90.913
2w2eA0.97443.70.914
2qgsA0.33333.60.915
4gc0A130.918
3zojA0.92312.90.919
1btqA0.15382.30.923
2wswA0.92311.80.926
3llqA0.89741.70.927
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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