GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF21 - Domain of unknown function DUF21
Pfam: PF01595 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 183
Sequences: 3794
Seq/Len: 20.73
HH_delta: 0.919 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
114_H117_K0.608492.838
127_R131_I0.602132.808
138_W142_F0.60012.799
13_S67_N0.496522.316
31_L45_L0.494322.305
146_K150_L0.48832.277
97_L143_I0.487862.275
44_R127_R0.46772.181
54_R134_Y0.467662.181
44_R124_P0.456292.128
30_R116_E0.440732.056
34_L120_L0.440732.056
35_A46_L0.435712.032
15_F125_L0.421411.965
142_F146_K0.418511.952
47_K127_R0.40741.900
16_F62_G0.400091.866
32_E36_E0.392021.828
121_R125_L0.38871.813
39_D120_L0.380671.775
117_K121_R0.377241.759
46_L50_E0.366961.711
19_A122_L0.359691.678
58_T129_L0.359691.678
124_P128_V0.343521.602
32_E46_L0.336791.571
122_L125_L0.335781.566
4_L8_L0.333411.555
35_A43_R0.332761.552
43_R47_K0.328191.531
31_L46_L0.327871.529
12_L66_S0.323211.507
38_G42_A0.317271.480
68_V71_G0.315481.471
13_S63_N0.312381.457
163_E167_R0.31111.451
45_L123_A0.305561.425
131_I134_Y0.304291.419
45_L119_A0.303691.416
44_R123_A0.296111.381
74_A78_A0.295861.380
15_F122_L0.291411.359
89_L93_L0.291221.358
6_A95_I0.290631.355
10_L98_L0.280821.310
142_F145_N0.278871.301
3_L7_L0.276661.290
20_E108_K0.275191.283
63_N67_N0.275091.283
59_I126_L0.274021.278
148_L153_I0.2741.278
173_G177_G0.273591.276
166_L173_G0.271691.267
162_S166_L0.26771.249
58_T137_V0.265261.237
13_S17_S0.262291.223
5_L8_L0.258841.207
74_A95_I0.25611.194
67_N99_I0.255241.190
63_N99_I0.252471.177
41_R120_L0.252381.177
41_R124_P0.252121.176
39_D42_A0.250981.171
48_L55_L0.250761.170
106_L147_I0.248681.160
17_S21_T0.24861.159
40_K43_R0.247941.156
18_A111_A0.24691.152
33_E37_E0.246481.150
60_L63_N0.246141.148
134_Y138_W0.241111.125
48_L123_A0.239961.119
130_M134_Y0.238141.111
70_A99_I0.237541.108
5_L73_L0.237461.107
21_T24_F0.234781.095
110_L153_I0.232951.086
44_R47_K0.230351.074
93_L97_L0.228861.067
72_V92_F0.226861.058
41_R45_L0.226041.054
18_A118_I0.22341.042
162_S165_E0.223251.041
31_L49_L0.221731.034
161_V169_L0.221481.033
72_V75_T0.221251.032
16_F129_L0.220991.031
14_A18_A0.21881.020
45_L49_L0.218031.017
54_R130_M0.217791.016
128_V131_I0.214731.001
34_L39_D0.213580.996
104_E108_K0.211190.985
68_V96_T0.20920.976
75_T79_S0.208740.974
125_L128_V0.207010.965
71_G75_T0.205240.957
24_F112_R0.202750.946
13_S66_S0.202420.944
21_T111_A0.201710.941
166_L179_I0.200370.934
53_E145_N0.199370.930
63_N104_E0.198290.925
6_A70_A0.198030.924
64_T92_F0.196920.918
60_L99_I0.196730.918
63_N103_G0.196720.917
47_K51_R0.195160.910
64_T108_K0.195140.910
42_A119_A0.194240.906
9_L69_L0.193970.905
17_S104_E0.193920.904
70_A95_I0.192440.898
73_L77_L0.19240.897
66_S96_T0.192010.896
18_A22_A0.191770.894
8_L12_L0.191230.892
75_T91_A0.189510.884
11_L151_F0.188560.879
135_P139_L0.187470.874
146_K149_K0.187110.873
118_I122_L0.185180.864
31_L42_A0.18490.862
63_N105_I0.184050.858
11_L14_A0.183770.857
72_V100_L0.182160.850
99_I105_I0.182150.850
145_N149_K0.181970.849
9_L19_A0.181350.846
35_A39_D0.180920.844
51_R54_R0.180880.844
58_T130_M0.180830.843
28_R164_E0.180580.842
30_R34_L0.178310.832
68_V75_T0.178240.831
32_E35_A0.178160.831
26_L115_P0.178020.830
73_L76_V0.177870.830
10_L14_A0.177840.829
52_P55_L0.17710.826
26_L116_E0.176460.823
64_T96_T0.175830.820
13_S59_I0.175390.818
64_T99_I0.175170.817
87_A91_A0.174630.814
141_S145_N0.174490.814
13_S99_I0.173450.809
21_T52_P0.17330.808
74_A77_L0.172590.805
64_T68_V0.172010.802
151_F154_E0.17180.801
55_L126_L0.171270.799
57_S165_E0.170320.794
17_S63_N0.169950.793
42_A120_L0.169290.790
175_E182_E0.168920.788
159_P176_E0.168140.784
121_R124_P0.167860.783
12_L16_F0.167350.780
68_V92_F0.167020.779
30_R33_E0.166860.778
28_R46_L0.166730.778
148_L152_G0.166150.775
21_T112_R0.165420.771
124_P127_R0.165380.771
83_G87_A0.165060.770
71_G92_F0.165030.770
7_L128_V0.164820.769
53_E109_A0.164650.768
6_A77_L0.164560.767
19_A126_L0.164440.767
129_L133_L0.163510.763
136_L140_L0.163370.762
77_L80_N0.163220.761
21_T25_S0.163210.761
113_R153_I0.162130.756
78_A81_L0.160870.750
41_R123_A0.160820.750
71_G115_P0.160680.749
149_K154_E0.160510.749
139_L142_F0.160480.748
110_L114_H0.159350.743
18_A140_L0.158850.741
91_A95_I0.158020.737
163_E183_E0.157730.736
17_S20_E0.157110.733
5_L9_L0.156470.730
4_L117_K0.156040.728
18_A122_L0.155730.726
59_I92_F0.155690.726
14_A92_F0.155440.725
86_W90_I0.155380.725
35_A38_G0.155330.724
56_L105_I0.155140.724
97_L140_L0.154930.723
17_S99_I0.154240.719
110_L118_I0.154210.719
41_R121_R0.153530.716
15_F62_G0.153490.716
9_L14_A0.152750.712
13_S60_L0.152210.710
6_A96_T0.152170.710
47_K50_E0.152010.709
88_L92_F0.151050.704
66_S73_L0.150950.704
56_L60_L0.150830.703
148_L155_N0.150650.703
174_E179_I0.150460.702
53_E141_S0.150230.701
52_P56_L0.150150.700
60_L67_N0.150060.700
42_A116_E0.149930.699
78_A82_F0.149870.699
63_N66_S0.149830.699
71_G96_T0.149570.698
54_R138_W0.149350.697
10_L13_S0.148320.692
61_L129_L0.148070.691
168_S172_E0.147910.690
132_L135_P0.147610.688
79_S169_L0.147240.687
61_L64_T0.147210.687
57_S140_L0.146890.685
167_R170_V0.14590.680
113_R144_S0.145150.677
25_S112_R0.145130.677
60_L71_G0.145020.676
7_L11_L0.144930.676
43_R46_L0.144930.676
174_E178_V0.144880.676
95_I98_L0.144560.674
80_N83_G0.144140.672
175_E181_E0.144120.672
64_T104_E0.143610.670
96_T100_L0.14340.669
116_E120_L0.143190.668
8_L127_R0.142950.667
24_F57_S0.141830.661
68_V72_V0.141820.661
10_L70_A0.141550.660
83_G86_W0.141510.660
56_L103_G0.141330.659
117_K120_L0.140870.657
168_S171_E0.140440.655
147_I151_F0.139940.653
109_A166_L0.139220.649
26_L81_L0.138830.647
100_L104_E0.138730.647
22_A119_A0.138490.646
43_R127_R0.138450.646
134_Y142_F0.137360.641
78_A91_A0.137140.640
70_A76_V0.136720.638
128_V132_L0.136530.637
115_P119_A0.136250.635
174_E181_E0.136070.635
28_R50_E0.136020.634
170_V173_G0.135890.634
58_T126_L0.13550.632
21_T105_I0.134870.629
26_L30_R0.134760.629
150_L154_E0.134650.628
58_T68_V0.134610.628
64_T100_L0.134250.626
68_V91_A0.134240.626
71_G76_V0.134090.625
11_L146_K0.133930.625
20_E64_T0.133660.623
35_A115_P0.133650.623
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3g5uA0.868927.70.919
4f4cA0.868923.90.921
3qf4B0.8634230.922
3pjsK0.803321.40.923
3um7A0.84719.80.924
2rsyB0.207719.30.925
3ug9A0.939919.30.925
3effK0.688518.10.925
3b60A0.863417.70.926
3b5xA0.863417.60.926
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

Page generated in 0.0373 seconds.