GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Acyl_transf_3 - Acyltransferase family
Pfam: PF01757 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0316
Length: 340
Sequences: 6854
Seq/Len: 20.16
HH_delta: 0.944 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
78_F82_L0.644113.517
9_G290_G0.593873.243
11_A51_L0.578243.158
288_F292_Y0.536232.928
135_F139_L0.493562.695
16_V296_I0.490052.676
61_A205_Y0.478582.613
5_D291_R0.433232.366
45_G48_A0.422532.307
50_P200_F0.41682.276
53_F138_A0.400532.187
74_L147_P0.39522.158
71_K75_K0.385082.103
9_G293_S0.383932.097
54_F207_L0.372272.033
70_W74_L0.36762.007
85_Y133_L0.361531.974
139_L143_Y0.351031.917
18_G45_G0.344011.879
15_V49_V0.335791.834
58_Y208_A0.333761.823
82_L86_L0.328731.795
4_I59_L0.327731.790
9_G289_L0.326351.782
300_H304_I0.325671.778
20_S304_I0.322421.761
56_S139_L0.312811.708
88_W299_I0.304531.663
132_H297_Y0.304141.661
5_D8_R0.303261.656
53_F139_L0.297691.626
75_K79_L0.294531.608
11_A48_A0.288881.577
18_G48_A0.284331.553
61_A208_A0.280271.530
91_I299_I0.276331.509
5_D287_S0.272271.487
69_S72_K0.264651.445
56_S201_F0.263461.439
70_W147_P0.263241.437
73_F143_Y0.263071.437
57_G204_G0.259221.416
61_A146_F0.258461.411
58_Y211_Y0.258391.411
73_F77_R0.25821.410
8_R55_I0.25721.404
6_G286_L0.256581.401
151_R155_K0.256571.401
288_F291_R0.253141.382
84_P298_L0.252841.381
4_I55_I0.252081.377
146_F201_F0.252051.376
12_I296_I0.249561.363
294_Y298_L0.24751.352
160_W163_L0.244141.333
131_G301_F0.243051.327
7_L51_L0.242181.322
45_G49_V0.240561.314
72_K76_K0.238091.300
9_G286_L0.237861.299
8_R135_F0.237081.295
130_N133_L0.235771.287
13_L17_F0.231531.264
15_V19_H0.227651.243
88_W92_Y0.226731.238
53_F134_W0.226111.235
49_V52_F0.22561.232
156_L159_R0.224691.227
72_K75_K0.222321.214
138_A142_F0.222091.213
144_L147_P0.221231.208
235_I239_Y0.219911.201
292_Y295_G0.219321.198
137_S141_Q0.218271.192
81_L140_F0.216841.184
9_G12_I0.216511.182
292_Y296_I0.21611.180
60_L143_Y0.215851.179
14_L18_G0.215691.178
79_L82_L0.215461.177
77_R143_Y0.214851.173
53_F135_F0.214611.172
286_L290_G0.214151.169
303_V307_L0.213211.164
63_S66_S0.211251.154
9_G13_L0.210751.151
92_Y302_P0.209521.144
82_L140_F0.209411.144
14_L48_A0.20891.141
205_Y209_R0.208821.140
54_F200_F0.207031.131
48_A142_F0.206861.130
14_L47_F0.206311.127
285_I289_L0.205511.122
129_C133_L0.205381.122
61_A209_R0.203831.113
224_L228_A0.20351.111
162_L165_L0.203431.111
18_G46_R0.201921.103
146_F205_Y0.200751.096
15_V48_A0.200281.094
88_W298_L0.199811.091
8_R294_Y0.198961.086
287_S291_R0.198261.083
227_L231_L0.197831.080
81_L143_Y0.19781.080
267_F271_L0.197621.079
12_I135_F0.196561.073
188_F191_F0.194831.064
12_I15_V0.19481.064
172_I175_Y0.193521.057
80_R139_L0.193241.055
231_L235_I0.1931.054
139_L294_Y0.192211.050
289_L296_I0.190321.039
268_L272_L0.18951.035
48_A143_Y0.18911.033
284_K287_S0.188831.031
223_I227_L0.18751.024
142_F201_F0.187421.023
60_L146_F0.187291.023
49_V139_L0.187161.022
190_W193_F0.186991.021
152_L155_K0.186731.020
84_P295_G0.186611.019
88_W130_N0.186241.017
235_I238_F0.186181.017
73_F146_F0.185981.016
78_F140_F0.185691.014
11_A49_V0.185581.013
9_G292_Y0.185381.012
49_V53_F0.185381.012
85_Y294_Y0.184451.007
154_K157_K0.184311.006
237_F241_F0.183361.001
60_L135_F0.183131.000
215_R219_R0.183010.999
129_C132_H0.182980.999
203_L263_F0.182330.996
228_A231_L0.182290.995
6_G10_I0.182290.995
138_A141_Q0.181830.993
134_W138_A0.181460.991
83_I294_Y0.181340.990
199_P202_L0.181320.990
142_F147_P0.18120.989
85_Y137_S0.181030.989
203_L267_F0.180950.988
299_I302_P0.180630.986
49_V134_W0.180530.986
210_Y214_I0.180390.985
156_L160_W0.179730.981
83_I143_Y0.179710.981
46_R50_P0.179490.980
295_G299_I0.178950.977
135_F138_A0.178260.973
49_V143_Y0.177920.972
265_G268_L0.177750.971
228_A238_F0.177490.969
77_R139_L0.176840.966
161_L164_L0.176670.965
87_F91_I0.176280.963
187_I190_W0.17620.962
236_L239_Y0.176190.962
262_L266_I0.175680.959
49_V294_Y0.175640.959
8_R139_L0.17550.958
285_I288_F0.175470.958
189_L193_F0.174770.954
18_G50_P0.17470.954
132_H300_H0.172770.943
135_F143_Y0.172640.943
19_H56_S0.172640.943
12_I139_L0.172070.940
53_F136_L0.171940.939
74_L140_F0.171890.939
71_K74_L0.170820.933
77_R83_I0.170620.932
9_G295_G0.169490.926
90_L94_V0.169150.924
12_I16_V0.168170.918
44_I50_P0.168140.918
53_F56_S0.16810.918
225_L228_A0.167990.917
73_F139_L0.16790.917
64_S67_R0.167730.916
7_L55_I0.167560.915
16_V300_H0.167490.915
12_I52_F0.167150.913
284_K288_F0.167150.913
73_F83_I0.167150.913
73_F147_P0.166930.912
85_Y130_N0.166510.909
201_F205_Y0.165680.905
132_H135_F0.165110.902
157_K160_W0.164060.896
307_L311_L0.163820.895
15_V53_F0.163750.894
60_L77_R0.163620.893
49_V80_R0.163450.893
209_R212_E0.163340.892
280_S283_K0.163240.891
84_P135_F0.162920.890
80_R295_G0.162760.889
65_K68_K0.162690.888
186_S190_W0.16250.887
155_K159_R0.16220.886
254_Y257_F0.16190.884
56_S59_L0.161880.884
94_V98_I0.16170.883
2_Y5_D0.161610.883
5_D133_L0.161480.882
8_R59_L0.160880.879
202_L205_Y0.160680.877
5_D290_G0.160670.877
141_Q145_L0.160440.876
84_P88_W0.160160.875
258_Y261_L0.160030.874
49_V135_F0.159490.871
211_Y214_I0.158570.866
59_L139_L0.158470.865
56_S60_L0.158410.865
188_F193_F0.158260.864
162_L166_I0.158210.864
128_S137_S0.158070.863
163_L166_I0.157850.862
124_F127_F0.157680.861
290_G293_S0.156950.857
77_R81_L0.156880.857
80_R84_P0.156770.856
15_V139_L0.156560.855
92_Y132_H0.156050.852
136_L298_L0.155660.850
15_V135_F0.155430.849
163_L167_L0.155390.849
60_L142_F0.155150.847
214_I217_R0.155130.847
217_R220_K0.154870.846
287_S290_G0.154670.845
88_W133_L0.154330.843
79_L83_I0.154120.842
5_D129_C0.154080.841
239_Y242_F0.154020.841
60_L139_L0.153950.841
302_P305_F0.15370.839
276_L279_R0.153250.837
189_L192_F0.153130.836
296_I300_H0.152470.833
6_G287_S0.152040.830
226_L230_L0.151390.827
8_R12_I0.151170.825
136_L294_Y0.150740.823
278_N281_S0.150620.822
262_L265_G0.149540.817
201_F208_A0.148640.812
18_G22_I0.148550.811
59_L295_G0.148460.811
211_Y215_R0.148270.810
6_G290_G0.148250.810
275_I278_N0.147980.808
277_P281_S0.147860.807
309_K313_P0.146730.801
266_I270_L0.146290.799
234_I238_F0.146010.797
65_K69_S0.145530.795
15_V59_L0.145260.793
158_R161_L0.145160.793
81_L139_L0.144890.791
221_Y224_L0.144880.791
133_L304_I0.144690.790
92_Y129_C0.144610.790
19_H300_H0.144550.789
48_A200_F0.144480.789
60_L140_F0.144160.787
80_R294_Y0.143960.786
3_W6_G0.143630.784
225_L229_L0.142820.780
80_R297_Y0.142110.776
47_F50_P0.141870.775
15_V297_Y0.141780.774
86_L90_L0.141140.771
80_R83_I0.140970.770
139_L292_Y0.140910.769
2_Y287_S0.140790.769
208_A211_Y0.140310.766
206_L209_R0.139980.764
13_L296_I0.139570.762
4_I135_F0.139510.762
81_L147_P0.139470.762
238_F242_F0.139470.762
50_P133_L0.138640.757
5_D85_Y0.138340.755
60_L84_P0.138180.755
171_L174_I0.137550.751
265_G272_L0.137470.751
201_F298_L0.137190.749
254_Y258_Y0.137060.748
75_K78_F0.137030.748
44_I48_A0.13650.745
74_L78_F0.136270.744
5_D76_K0.136010.743
13_L289_L0.135560.740
12_I48_A0.135370.739
143_Y201_F0.135330.739
143_Y295_G0.135120.738
187_I193_F0.134770.736
95_L99_V0.134770.736
167_L171_L0.134560.735
57_G165_L0.134380.734
91_I95_L0.134230.733
102_S105_P0.134050.732
12_I49_V0.134010.732
220_K224_L0.133850.731
132_H298_L0.133730.730
305_F309_K0.133630.730
83_I139_L0.133110.727
5_D9_G0.13280.725
236_L240_F0.132450.723
106_S109_F0.13230.722
279_R283_K0.131980.721
140_F201_F0.131180.716
43_F46_R0.13050.713
77_R80_R0.130440.712
60_L201_F0.130260.711
219_R222_L0.130170.711
152_L156_L0.129990.710
301_F304_I0.129870.709
260_L264_L0.129850.709
133_L137_S0.129680.708
256_S262_L0.129640.708
209_R213_R0.129560.707
56_S77_R0.129510.707
167_L217_R0.129050.705
200_F263_F0.128970.704
161_L165_L0.128920.704
259_L262_L0.128760.703
265_G273_L0.128570.702
18_G49_V0.128260.700
132_H301_F0.128070.699
141_Q144_L0.12760.697
264_L268_L0.12750.696
186_S189_L0.127270.695
92_Y306_I0.127180.694
18_G134_W0.126910.693
5_D295_G0.126860.693
204_G208_A0.126790.692
53_F80_R0.126730.692
73_F142_F0.126730.692
3_W270_L0.126650.692
94_V97_W0.126610.691
49_V136_L0.126520.691
92_Y301_F0.126430.690
237_F240_F0.126390.690
232_L236_L0.12630.690
69_S73_F0.125920.688
142_F146_F0.12580.687
8_R19_H0.125580.686
160_W166_I0.125480.685
91_I182_G0.125190.684
218_R222_L0.125140.683
15_V132_H0.124730.681
284_K291_R0.124030.677
107_F111_L0.124010.677
215_R218_R0.123940.677
21_F24_Y0.123880.676
60_L73_F0.123830.676
6_G132_H0.123360.674
307_L310_L0.123290.673
96_S108_L0.123260.673
140_F144_L0.123170.673
8_R81_L0.123060.672
60_L297_Y0.1230.672
210_Y213_R0.12280.671
137_S200_F0.122750.670
231_L234_I0.122640.670
3_W273_L0.122610.670
46_R132_H0.122340.668
88_W91_I0.122060.667
294_Y304_I0.121920.666
46_R49_V0.121910.666
69_S76_K0.12180.665
139_L201_F0.121780.665
216_K221_Y0.12170.665
223_I226_L0.121580.664
306_I309_K0.12140.663
56_S135_F0.121370.663
234_I237_F0.121320.662
238_F241_F0.121140.662
81_L293_S0.120660.659
8_R77_R0.120370.657
161_L203_L0.120260.657
164_L168_L0.120210.656
202_L206_L0.120140.656
254_Y259_L0.119850.654
271_L275_I0.119760.654
174_I178_I0.119750.654
110_L113_L0.119560.653
21_F49_V0.119540.653
45_G50_P0.118980.650
173_L176_I0.118950.650
93_F96_S0.118870.649
206_L269_L0.11880.649
134_W300_H0.118490.647
147_P151_R0.118430.647
11_A143_Y0.118230.646
97_W144_L0.118210.646
276_L280_S0.117910.644
277_P280_S0.117610.642
148_L152_L0.117570.642
303_V306_I0.117490.642
108_L112_L0.117330.641
222_L226_L0.117180.640
293_S296_I0.117160.640
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4hfiA0.28536.30.944
3vr8D0.22351.80.957
1rklA0.08531.70.957
2latA0.08821.60.957
2iubA0.18821.30.96
4ev6A0.18821.30.96
1jdmA0.07941.20.96
2lulA0.15291.20.96
3w5aC0.07941.20.96
4i0uA0.188210.962
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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