GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Ferric_reduct - Ferric reductase like transmembrane component
Pfam: PF01794 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0328
Length: 125
Sequences: 2354
Seq/Len: 18.83
HH_delta: 0.883 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
5_A48_A0.670823.832
52_G87_L0.536863.067
45_F94_A0.459432.624
98_F101_I0.420732.403
49_L87_L0.410642.346
34_L38_R0.320991.834
15_L33_L0.297121.697
109_I113_L0.290031.657
9_L121_F0.284021.622
12_V44_A0.279661.598
116_L120_A0.27341.562
48_A52_G0.272071.554
89_L120_A0.270591.546
48_A87_L0.269231.538
45_F91_L0.257431.471
90_L121_F0.256941.468
116_L119_I0.242421.385
106_N109_I0.24221.384
109_I112_Y0.238971.365
81_L85_I0.235631.346
4_L7_A0.233931.336
119_I123_L0.231611.323
37_H114_H0.227811.301
39_W42_R0.225921.291
55_Y58_N0.22291.273
57_I62_F0.216531.237
93_L96_T0.215851.233
73_A77_G0.215721.232
108_E112_Y0.212131.212
96_T113_L0.212111.212
43_L47_L0.210031.200
53_V57_I0.208961.194
39_W43_L0.206131.177
112_Y115_I0.205621.175
10_P44_A0.204541.168
107_Y110_F0.204371.167
4_L8_L0.204171.166
71_F75_L0.201511.151
97_S110_F0.201381.150
49_L91_L0.199371.139
75_L84_I0.197471.128
13_F16_G0.197141.126
49_L53_V0.196191.121
92_I117_F0.194631.112
70_W74_W0.194341.110
111_Y115_I0.193291.104
16_G34_L0.192931.102
78_P82_T0.191081.092
52_G84_I0.188981.080
102_R111_Y0.181541.037
30_F33_L0.181511.037
110_F113_L0.18021.029
41_G111_Y0.180151.029
72_N76_T0.17781.016
82_T86_A0.177251.013
17_L21_P0.177091.012
119_I122_L0.176861.010
78_P81_L0.174960.999
92_I116_L0.174310.996
5_A47_L0.173680.992
45_F87_L0.173190.989
48_A86_A0.172080.983
13_F117_F0.170530.974
28_I107_Y0.168390.962
3_I7_A0.168310.961
81_L88_L0.167310.956
89_L121_F0.166180.949
85_I89_L0.165870.948
50_L83_G0.164650.941
100_W104_R0.16430.939
47_L50_L0.163480.934
41_G45_F0.163440.934
8_L47_L0.163050.931
57_I61_R0.161540.923
12_V17_L0.160960.919
115_I119_I0.160260.915
84_I88_L0.159740.912
96_T117_F0.159450.911
70_W73_A0.158160.903
46_F50_L0.158060.903
27_G122_L0.157550.900
4_L13_F0.157240.898
6_F48_A0.156420.894
23_A28_I0.15410.880
92_I113_L0.153510.877
69_E72_N0.153020.874
15_L40_L0.151390.865
24_R95_V0.151240.864
59_W80_N0.150390.859
91_L123_L0.150240.858
24_R28_I0.149160.852
43_L46_F0.147940.845
29_S38_R0.14750.843
53_V78_P0.14750.843
37_H107_Y0.147440.842
18_R23_A0.146890.839
83_G114_H0.146840.839
93_L97_S0.145910.833
22_L26_T0.145270.830
17_L23_A0.144790.827
107_Y114_H0.144610.826
105_R109_I0.144150.823
90_L94_A0.144140.823
55_Y70_W0.144060.823
73_A79_Y0.143390.819
42_R46_F0.142830.816
60_L70_W0.142280.813
95_V101_I0.142180.812
7_A10_P0.14210.812
59_W70_W0.141470.808
31_D34_L0.141260.807
27_G32_R0.1410.805
52_G110_F0.13950.797
5_A8_L0.139030.794
73_A76_T0.138560.792
9_L13_F0.138390.791
41_G97_S0.137350.785
88_L92_I0.136950.782
77_G119_I0.136730.781
13_F36_F0.13650.780
74_W92_I0.136240.778
87_L91_L0.136140.778
74_W87_L0.135060.772
9_L92_I0.134140.766
49_L76_T0.133970.765
112_Y123_L0.133190.761
3_I55_Y0.133080.760
107_Y111_Y0.132860.759
22_L33_L0.132440.757
56_L84_I0.131310.750
93_L117_F0.130860.748
30_F34_L0.130490.745
54_L57_I0.130440.745
53_V70_W0.130190.744
78_P122_L0.130060.743
77_G80_N0.12960.740
2_G123_L0.128940.737
88_L105_R0.128810.736
75_L79_Y0.128710.735
52_G56_L0.128630.735
19_N38_R0.128180.732
49_L99_P0.1280.731
8_L12_V0.126980.725
4_L80_N0.126980.725
16_G38_R0.126720.724
74_W77_G0.126470.722
30_F117_F0.126150.721
99_P104_R0.125930.719
108_E111_Y0.125550.717
26_T84_I0.125510.717
77_G82_T0.125470.717
30_F118_Y0.125010.714
34_L99_P0.124610.712
106_N113_L0.12420.709
113_L117_F0.12410.709
117_F122_L0.12410.709
49_L90_L0.124090.709
5_A44_A0.124080.709
91_L96_T0.123940.708
43_L54_L0.123920.708
101_I113_L0.123650.706
6_F22_L0.123590.706
82_T123_L0.123420.705
93_L107_Y0.123330.705
102_R107_Y0.123270.704
6_F9_L0.123110.703
41_G122_L0.122750.701
79_Y83_G0.122710.701
22_L105_R0.122310.699
5_A12_V0.121760.696
23_A33_L0.121560.694
68_Q75_L0.121490.694
85_I120_A0.120590.689
20_S41_G0.120470.688
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1iijA0.2817.10.883
2iubA0.4649.40.895
4h44A0.9048.50.897
4i0uA0.4646.70.902
4ev6A0.4646.40.902
3ixzA0.8325.60.905
1kqfC0.9523.80.912
3kp9A0.81630.915
2l2tA0.3442.80.917
3j2wE0.3682.70.918
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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