GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
LysE - LysE type translocator
Pfam: PF01810 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0292
Length: 191
Sequences: 8340
Seq/Len: 43.66
HH_delta: 0.919 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
35_L101_F1.722154.950
74_G181_I1.213193.487
171_W174_R1.051623.022
71_L184_A0.870182.501
75_Y79_R0.828982.383
74_G177_G0.815842.345
67_A188_L0.81362.338
67_A184_A0.798292.294
64_L68_L0.785882.259
60_M63_K0.76792.207
39_I105_F0.735952.115
71_L181_I0.728922.095
18_G26_G0.727242.090
78_L177_G0.703922.023
131_S134_Q0.641511.844
178_L182_G0.640611.841
171_W175_I0.630291.811
78_L174_R0.608041.748
146_S150_F0.574811.652
64_L67_A0.557721.603
64_L188_L0.551.581
17_N21_K0.547331.573
37_D108_N0.5461.569
71_L75_Y0.545071.567
36_G105_F0.543261.561
59_F63_K0.542881.560
36_G109_L0.534521.536
161_R165_S0.530141.524
60_M64_L0.525861.511
57_W60_M0.513111.475
102_L106_L0.507771.459
72_Y76_K0.50551.453
31_L101_F0.50081.439
41_I139_I0.496311.426
174_R178_L0.492951.417
105_F109_L0.478941.376
69_Y72_Y0.476921.371
149_W153_L0.473421.361
29_V104_G0.468731.347
26_G154_A0.467561.344
25_A100_S0.462931.330
159_R163_K0.460941.325
23_F155_L0.445441.280
98_S102_L0.442271.271
18_G154_A0.439541.263
69_Y73_L0.435331.251
37_D40_Y0.433831.247
14_V18_G0.433471.246
101_F105_F0.43211.242
26_G30_A0.43191.241
136_L139_I0.431311.240
42_L46_F0.42851.232
78_L181_I0.422171.213
74_G184_A0.416091.196
138_F142_I0.415811.195
58_L61_I0.415411.194
133_T136_L0.413211.188
96_S99_K0.41271.186
15_I157_G0.411411.182
37_D114_A0.41121.182
17_N29_V0.409331.176
35_L39_I0.40841.174
30_A154_A0.407581.171
177_G181_I0.402611.157
118_W142_I0.400041.150
163_K166_S0.396161.139
152_L156_L0.390741.123
28_P97_K0.390721.123
76_K79_R0.390721.123
57_W61_I0.382171.098
151_L155_L0.381671.097
38_L143_F0.380381.093
40_Y108_N0.379691.091
138_F141_G0.378461.088
181_I185_V0.378241.087
32_G104_G0.377491.085
159_R162_R0.376351.082
61_I64_L0.372481.071
50_A54_S0.372451.070
36_G108_N0.370021.063
30_A34_A0.367891.057
69_Y113_K0.362871.043
32_G101_F0.355031.020
52_L55_S0.351471.010
14_V150_F0.351441.010
67_A71_L0.349071.003
157_G160_L0.349031.003
17_N103_T0.348471.002
99_K102_L0.347760.999
61_I65_L0.347030.997
37_D104_G0.339170.975
55_S58_L0.330260.949
33_A37_D0.329530.947
74_G78_L0.329420.947
28_P100_S0.329390.947
107_L110_L0.327340.941
132_S135_F0.326870.939
47_G50_A0.32390.931
181_I184_A0.323420.930
129_E134_Q0.322430.927
68_L72_Y0.321970.925
22_G26_G0.321850.925
14_V33_A0.319730.919
153_L157_G0.317330.912
17_N20_R0.315160.906
182_G186_Y0.314220.903
136_L140_L0.313850.902
25_A28_P0.313330.901
72_Y75_Y0.31220.897
166_S169_I0.310410.892
40_Y44_A0.309120.888
120_A124_Q0.308280.886
47_G52_L0.303450.872
130_Y134_Q0.303130.871
14_V29_V0.302190.869
186_Y189_Y0.301530.867
24_K97_K0.300690.864
41_I135_F0.300650.864
71_L188_L0.299790.862
79_R82_F0.297090.854
21_K25_A0.29450.846
172_I176_S0.294220.846
33_A114_A0.292480.841
110_L119_L0.292230.840
33_A146_S0.291860.839
164_F167_R0.291450.838
34_A143_F0.29120.837
32_G41_I0.290120.834
130_Y133_T0.289860.833
142_I146_S0.289680.833
118_W122_F0.2890.831
183_F186_Y0.288910.830
104_G108_N0.285910.822
162_R166_S0.285560.821
146_S153_L0.285270.820
27_L30_A0.284780.818
37_D118_W0.283770.816
16_S20_R0.282990.813
81_K174_R0.281990.810
80_S173_N0.281850.810
156_L159_R0.278550.801
37_D142_I0.278510.800
163_K167_R0.277630.798
36_G40_Y0.277140.797
141_G145_G0.275660.792
108_N150_F0.274990.790
30_A151_L0.273710.787
114_A150_F0.27360.786
35_L105_F0.272920.784
175_I178_L0.270490.777
146_S149_W0.269120.773
37_D146_S0.268690.772
144_L148_L0.268520.772
81_K84_S0.268120.771
84_S87_S0.267650.769
36_G113_K0.267620.769
75_Y181_I0.267250.768
118_W146_S0.267170.768
55_S59_F0.266270.765
149_W152_L0.265950.764
24_K28_P0.265750.764
108_N114_A0.264060.759
73_L113_K0.262020.753
176_S180_L0.261520.752
29_V107_L0.261490.752
117_F123_P0.261430.751
155_L159_R0.260820.750
153_L156_L0.260140.748
41_I150_F0.260110.748
114_A146_S0.260.747
37_D150_F0.260.747
30_A150_F0.258980.744
117_F121_V0.258580.743
68_L71_L0.257750.741
185_V189_Y0.256530.737
122_F126_I0.256060.736
40_Y109_L0.255960.736
23_F159_R0.254410.731
41_I118_W0.254270.731
44_A115_I0.254090.730
91_E95_Q0.253940.730
32_G35_L0.25360.729
156_L160_L0.252280.725
14_V108_N0.252240.725
169_I172_I0.25210.725
150_F154_A0.251190.722
84_S92_A0.250180.719
143_F146_S0.248590.714
103_T106_L0.248260.714
30_A33_A0.248240.713
31_L35_L0.248020.713
27_L151_L0.246870.710
49_S52_L0.243070.699
95_Q99_K0.242320.696
34_A147_L0.242080.696
35_L38_L0.241790.695
134_Q137_V0.241050.693
34_A38_L0.240620.692
28_P31_L0.240360.691
19_L157_G0.24020.690
121_V125_F0.239860.689
147_L151_L0.238610.686
37_D107_L0.238110.684
37_D41_I0.237280.682
52_L56_P0.23710.681
37_D110_L0.237050.681
77_L176_S0.235920.678
110_L146_S0.23570.677
100_S103_T0.23510.676
150_F153_L0.232930.669
56_P59_F0.232450.668
20_R23_F0.230270.662
27_L31_L0.230220.662
82_F85_K0.230120.661
88_T91_E0.229990.661
23_F151_L0.229530.660
165_S169_I0.229070.658
33_A108_N0.228910.658
48_L52_L0.228590.657
23_F158_S0.227680.654
121_V138_F0.227380.654
162_R165_S0.226450.651
117_F146_S0.226330.650
140_L144_L0.225310.648
77_L174_R0.225210.647
18_G114_A0.22510.647
55_S60_M0.224170.644
123_P126_I0.223810.643
119_L122_F0.223550.642
56_P60_M0.223540.642
154_A157_G0.222590.640
142_I148_L0.222060.638
148_L151_L0.221340.636
29_V100_S0.221030.635
168_R171_W0.220210.633
73_L77_L0.220010.632
161_R164_F0.219710.631
71_L74_G0.218710.629
72_Y113_K0.217740.626
33_A118_W0.217170.624
30_A147_L0.215550.620
143_F150_F0.215420.619
38_L147_L0.214920.618
14_V145_G0.213920.615
135_F142_I0.213910.615
140_L143_F0.21310.612
23_F26_G0.213070.612
122_F125_F0.21290.612
49_S53_K0.212560.611
26_G33_A0.211320.607
134_Q138_F0.210850.606
40_Y115_I0.210550.605
47_G70_L0.210460.605
15_I153_L0.21030.604
157_G161_R0.20950.602
85_K88_T0.20940.602
23_F154_A0.208930.600
78_L178_L0.208710.600
163_K169_I0.20630.593
99_K103_T0.206110.592
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3o7qA0.942414.20.919
2gfpA0.905810.90.923
3j1zP0.88489.40.925
2m67A0.39797.40.928
1pw4A0.94767.40.928
4iu9B0.95296.70.93
4j05A0.57595.30.933
4jr9A0.968650.933
1bzkA0.22513.50.938
4ainA0.56023.20.939
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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