GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
WSC - WSC domain
Pfam: PF01822 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 82
Sequences: 1404
Seq/Len: 17.12
HH_delta: 0.879 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
34_C52_C1.096914.904
27_P44_L0.97944.379
31_A42_A0.823843.683
48_N73_P0.592172.648
27_P78_Q0.525982.352
75_D78_Q0.519182.321
72_C80_C0.446061.994
46_N49_E0.415061.856
28_E78_Q0.403271.803
47_G70_M0.397861.779
71_P79_T0.387131.731
63_V67_S0.370161.655
46_N70_M0.365871.636
7_D45_E0.344091.538
13_P16_S0.317291.419
25_M74_G0.3041.359
45_E51_Y0.302481.352
12_S15_L0.294431.316
42_A52_C0.292691.309
39_Y54_N0.289131.293
24_D29_K0.288521.290
43_G53_G0.287531.286
23_D48_N0.275121.230
25_M29_K0.270481.209
7_D14_L0.268671.201
45_E49_E0.267761.197
18_A33_H0.260191.163
40_P54_N0.259031.158
56_L59_D0.255421.142
59_D62_Q0.250311.119
56_L60_S0.242551.084
64_D67_S0.240221.074
31_A35_R0.236891.059
65_S79_T0.236081.056
25_M44_L0.230351.030
27_P42_A0.23031.030
68_C72_C0.22861.022
29_K32_E0.224931.006
53_G57_P0.220120.984
22_S25_M0.219940.983
2_L41_Y0.214270.958
7_D51_Y0.211270.945
33_H37_K0.205490.919
28_E32_E0.202890.907
13_P49_E0.199540.892
26_T75_D0.198450.887
12_S16_S0.195830.876
68_C81_G0.19330.864
54_N69_N0.192390.860
13_P45_E0.184630.825
17_P20_S0.183420.820
21_S24_D0.180970.809
30_C50_C0.179210.801
68_C80_C0.177950.796
71_P76_P0.177770.795
2_L60_S0.17730.793
8_S82_G0.176630.790
70_M82_G0.176290.788
62_Q65_S0.173690.777
39_Y42_A0.172340.771
69_N79_T0.172160.770
66_S77_S0.171430.766
53_G61_S0.170380.762
21_S49_E0.168130.752
17_P29_K0.166430.744
20_S25_M0.164330.735
27_P75_D0.164120.734
21_S48_N0.162860.728
2_L35_R0.161590.722
69_N82_G0.160360.717
41_Y58_S0.160160.716
2_L59_D0.159240.712
59_D63_V0.155580.696
6_S63_V0.154120.689
13_P46_N0.153940.688
43_G75_D0.153520.686
40_P56_L0.152830.683
39_Y43_G0.15110.676
42_A45_E0.148260.663
16_S41_Y0.147740.661
33_H38_G0.146180.654
7_D49_E0.14490.648
58_S61_S0.143310.641
29_K33_H0.142220.636
31_A55_S0.141460.632
74_G80_C0.139740.625
3_G41_Y0.139260.623
27_P32_E0.138790.621
38_G77_S0.138110.617
72_C81_G0.136940.612
23_D73_P0.136790.612
8_S60_S0.13570.607
16_S55_S0.13560.606
32_E35_R0.135480.606
55_S69_N0.13530.605
52_C72_C0.13480.603
8_S12_S0.133970.599
36_A67_S0.133260.596
40_P77_S0.132650.593
3_G42_A0.132380.592
27_P43_G0.132040.590
7_D13_P0.131870.590
14_L45_E0.131230.587
34_C42_A0.130220.582
23_D47_G0.129460.579
68_C74_G0.129450.579
50_C68_C0.12930.578
41_Y62_Q0.128270.573
27_P31_A0.128140.573
5_Y62_Q0.127960.572
7_D12_S0.127750.571
11_S22_S0.126820.567
50_C72_C0.126350.565
2_L56_L0.126180.564
46_N73_P0.125810.562
5_Y57_P0.125290.560
7_D43_G0.12410.555
20_S61_S0.123770.553
6_S29_K0.123170.551
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3m7qB0.30498.10.879
2yilA0.96346.50.884
1bf0A0.29276.40.884
2kozA0.40246.40.884
3aubA0.29275.50.888
3v64A0.40245.10.889
2jotA0.292750.89
1co7I0.3784.50.892
1aapA0.29274.30.893
1g6xA0.29274.10.893
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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