GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
FTH - FTH domain
Pfam: PF01827 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 142
Sequences: 1005
Seq/Len: 7.08
HH_delta: 0.907 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
94_F122_F0.536874.061
70_A91_F0.497283.762
45_E71_K0.449463.400
47_I70_A0.449053.397
71_K92_E0.40353.052
18_K40_D0.381212.884
33_L37_P0.323122.444
20_K45_E0.312662.365
72_E93_K0.302692.290
42_G69_N0.291512.205
19_V39_L0.264181.999
21_K46_E0.262261.984
73_F88_F0.258721.957
86_E108_K0.2381.800
73_F91_F0.226961.717
40_D69_N0.218261.651
66_Q70_A0.217471.645
119_F122_F0.213561.616
92_E120_K0.198891.505
46_E72_E0.194211.469
65_E69_N0.192051.453
85_L89_S0.184411.395
107_W111_E0.1781.347
91_F94_F0.177931.346
67_W91_F0.177381.342
58_F61_I0.170511.290
62_V67_W0.170441.289
116_S119_F0.16991.285
49_I70_A0.16891.278
41_P44_L0.165151.249
101_I108_K0.161121.219
84_P87_N0.159931.210
41_P65_E0.15831.198
87_N90_H0.157441.191
105_D108_K0.155561.177
60_E63_E0.154411.168
16_K41_P0.151951.149
87_N109_L0.150131.136
8_Q12_K0.147031.112
19_V22_L0.146911.111
91_F109_L0.145161.098
29_Q59_D0.139351.054
37_P66_Q0.13751.040
113_L119_F0.137111.037
95_N123_R0.135941.028
107_W110_K0.134041.014
101_I106_I0.132181.000
7_L10_I0.131160.992
16_K40_D0.12970.981
23_K48_R0.128950.976
73_F94_F0.128290.971
35_I121_Y0.128070.969
9_E12_K0.127740.966
94_F119_F0.127060.961
36_L64_L0.122220.925
102_T105_D0.120910.915
66_Q86_E0.120050.908
110_K113_L0.119860.907
109_L122_F0.119150.901
21_K102_T0.119110.901
47_I66_Q0.118770.898
6_K9_E0.118270.895
110_K114_L0.118120.894
44_L66_Q0.117270.887
62_V87_N0.117240.887
17_L65_E0.115320.872
63_E87_N0.115310.872
41_P70_A0.115220.872
10_I24_I0.114230.864
96_I124_I0.113710.860
27_L109_L0.113340.857
30_S60_E0.113250.857
17_L39_L0.112650.852
6_K10_I0.112340.850
49_I75_I0.111520.844
49_I116_S0.111220.841
94_F115_K0.110910.839
94_F113_L0.109520.829
26_S56_E0.108870.824
35_I112_N0.108770.823
89_S112_N0.107840.816
46_E74_K0.107440.813
7_L53_E0.107110.810
33_L61_I0.106910.809
67_W90_H0.106390.805
91_F106_I0.106260.804
58_F89_S0.105190.796
70_A120_K0.105170.796
29_Q33_L0.104740.792
59_D63_E0.10430.789
49_I103_V0.103880.786
12_K44_L0.103810.785
55_E64_L0.103580.784
49_I99_E0.103010.779
39_L43_V0.101920.771
74_K77_G0.101880.771
56_E94_F0.101490.768
114_L121_Y0.101360.767
28_N73_F0.101350.767
10_I16_K0.101350.767
74_K95_N0.10050.760
85_L108_K0.100260.758
89_S122_F0.100210.758
104_E108_K0.09980.755
18_K44_L0.098760.747
119_F124_I0.098590.746
76_G124_I0.097930.741
35_I38_F0.097930.741
6_K98_F0.096410.729
22_L32_V0.096350.729
102_T107_W0.096130.727
9_E103_V0.096060.727
43_V53_E0.095730.724
15_H81_D0.095540.723
37_P60_E0.094820.717
54_E110_K0.094630.716
109_L119_F0.093940.711
47_I79_V0.093540.708
48_R75_I0.093490.707
62_V98_F0.093340.706
12_K61_I0.092290.698
6_K89_S0.091880.695
31_E82_S0.091670.693
7_L17_L0.091620.693
30_S40_D0.091370.691
80_I113_L0.091280.691
21_K29_Q0.091010.688
22_L47_I0.090740.686
44_L52_E0.090650.686
11_L19_V0.090490.685
22_L70_A0.090370.684
51_D100_S0.090340.683
117_P124_I0.090320.683
26_S106_I0.090280.683
9_E96_I0.090140.682
111_E115_K0.090030.681
74_K121_Y0.089820.679
95_N111_E0.089780.679
85_L88_F0.089240.675
93_K120_K0.089120.674
39_L85_L0.088680.671
93_K110_K0.088620.670
33_L38_F0.08860.670
42_G94_F0.088090.666
35_I58_F0.088090.666
106_I110_K0.087670.663
47_I68_K0.087650.663
27_L106_I0.087280.660
76_G100_S0.087160.659
108_K111_E0.087150.659
113_L122_F0.087130.659
20_K78_F0.08710.659
97_H111_E0.086920.658
89_S94_F0.086840.657
108_K119_F0.086480.654
32_V113_L0.086130.652
14_K32_V0.085980.650
10_I26_S0.085920.650
6_K51_D0.085810.649
52_E96_I0.085730.649
64_L91_F0.085590.647
32_V90_H0.08550.647
86_E89_S0.085250.645
42_G45_E0.084320.638
32_V45_E0.084150.637
17_L38_F0.084080.636
25_N111_E0.084020.636
78_F81_D0.083840.634
82_S86_E0.083740.633
33_L64_L0.083620.633
91_F110_K0.083510.632
10_I23_K0.083450.631
82_S98_F0.083340.630
40_D43_V0.083260.630
93_K123_R0.083120.629
26_S31_E0.082780.626
14_K17_L0.082570.625
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2ca6A0.964820.30.907
1io0A0.985918.70.909
3un9A0.978915.90.912
1z7xW0.978912.50.915
4aybB0.3451120.916
2p0oA0.929611.40.917
3ogkB0.95779.60.919
3gozA0.98597.60.923
3h0gB0.37327.40.923
1bhdA0.72546.30.925
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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