GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
60KD_IMP - 60Kd inner membrane protein
Pfam: PF02096 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0376
Length: 198
Sequences: 2186
Seq/Len: 11.04
HH_delta: 0.944 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
56_E59_K0.799814.106
128_G165_L0.74553.827
59_K63_K0.745063.825
38_E41_E0.705073.619
40_K43_Q0.683913.511
36_Q40_K0.604793.104
42_I53_M0.576242.958
130_S183_N0.502012.577
52_K56_E0.495672.544
40_K44_E0.478542.456
105_W113_D0.473212.429
86_F90_R0.454022.331
126_L180_I0.445462.287
52_K55_Q0.428572.200
35_L66_V0.423422.173
8_I181_T0.412852.119
51_Q55_Q0.396132.033
38_E63_K0.390432.004
38_E64_H0.348171.787
79_I83_I0.345481.773
83_I87_R0.344591.769
41_E45_K0.3381.735
19_L23_I0.337341.732
39_L57_M0.336451.727
163_M167_F0.335331.721
121_F124_P0.325671.672
23_I27_R0.324031.663
49_D52_K0.320371.645
42_I60_L0.319411.640
5_L9_L0.313461.609
35_L60_L0.310661.595
53_M57_M0.309671.590
5_L8_I0.30711.576
188_L192_I0.303461.558
43_Q53_M0.301591.548
16_L185_F0.294541.512
18_L81_I0.292471.501
87_R91_R0.291721.497
87_R90_R0.289211.485
30_A33_Q0.278051.427
31_K34_E0.275361.413
108_D111_A0.272611.399
45_K56_E0.269641.384
50_Q54_Q0.261761.344
5_L103_F0.257641.323
55_Q59_K0.256831.318
43_Q47_K0.254771.308
160_M163_M0.252471.296
27_R31_K0.251671.292
47_K50_Q0.251621.292
184_L188_L0.247841.272
150_A153_M0.247781.272
76_L80_P0.247491.270
166_F170_F0.243551.250
134_N186_S0.241081.238
54_Q58_Q0.240051.232
168_T176_F0.236581.214
75_P79_I0.233171.197
149_Q152_M0.232271.192
171_F179_W0.227191.166
132_F136_E0.226881.165
191_L195_R0.226251.161
179_W183_N0.225391.157
159_I163_M0.223961.150
24_K27_R0.220171.130
125_I129_A0.218871.123
57_M61_Y0.217111.114
54_Q57_M0.217031.114
20_P24_K0.215091.104
41_E44_E0.213911.098
59_K62_K0.212421.090
105_W119_P0.211231.084
129_A133_L0.210361.080
10_T85_L0.20951.075
103_F106_F0.208941.073
82_F186_S0.208041.068
152_M155_I0.207611.066
123_L177_L0.203191.043
152_M156_M0.203161.043
7_I174_A0.202911.042
79_I82_F0.201091.032
134_N187_L0.199421.024
8_I177_L0.199351.023
183_N186_S0.199251.023
121_F169_S0.199221.023
15_R18_L0.199061.022
112_P121_F0.199051.022
113_D121_F0.198471.019
150_A154_K0.197691.015
165_L169_S0.195511.004
39_L60_L0.193620.994
15_R186_S0.190750.979
132_F158_Y0.190150.976
42_I46_Y0.189430.972
137_L191_L0.187030.960
182_S186_S0.184290.946
136_E157_L0.183710.943
151_K154_K0.181680.933
130_S184_L0.180880.928
159_I162_L0.180390.926
154_K158_Y0.180050.924
136_E140_K0.17870.917
75_P78_Q0.178510.916
11_T182_S0.173380.890
60_L64_H0.171720.881
106_F123_L0.170120.873
50_Q58_Q0.170050.873
123_L173_A0.169330.869
15_R22_S0.167330.859
13_L17_I0.166720.856
136_E158_Y0.16520.848
167_F171_F0.164890.846
18_L78_Q0.164590.845
192_I195_R0.164410.844
130_S187_L0.16410.842
82_F182_S0.163720.840
162_L165_L0.1620.832
126_L130_S0.161950.831
50_Q53_M0.161760.830
180_I184_L0.161430.829
13_L16_L0.160080.822
105_W173_A0.159990.821
102_G106_F0.159150.817
148_Q153_M0.159010.816
23_I193_L0.158070.811
15_R189_Q0.157930.811
15_R182_S0.157470.808
19_L192_I0.155230.797
155_I159_I0.154630.794
71_G74_P0.154260.792
14_V85_L0.153590.788
119_P122_I0.15280.784
25_Q29_S0.152660.784
46_Y52_K0.152650.784
171_F175_L0.15180.779
124_P175_L0.149740.769
29_S32_M0.148840.764
163_M166_F0.148090.760
130_S180_I0.147340.756
67_N72_C0.146910.754
192_I196_P0.146890.754
46_Y49_D0.146720.753
25_Q81_I0.146510.752
113_D173_A0.14590.749
168_T179_W0.145220.745
22_S193_L0.145140.745
39_L42_I0.145010.744
127_A164_F0.144380.741
173_A176_F0.143990.739
134_N137_L0.143720.738
51_Q54_Q0.143350.736
152_M157_L0.142380.731
112_P169_S0.142370.731
84_G89_L0.142090.729
157_L186_S0.141580.727
9_L13_L0.141570.727
35_L64_H0.140510.721
85_L174_A0.14050.721
130_S133_L0.140440.721
26_Q30_A0.140190.720
74_P161_P0.140070.719
4_G103_F0.139120.714
4_G8_I0.138870.713
42_I57_M0.137910.708
3_W92_M0.137850.708
2_S6_A0.137680.707
112_P120_Y0.137620.706
177_L181_T0.136060.698
132_F157_L0.135460.695
3_W6_A0.135450.695
113_D119_P0.135250.694
68_P71_G0.135180.694
24_K31_K0.134690.691
38_E60_L0.134480.690
11_T20_P0.134430.690
104_L107_P0.133280.684
122_I126_L0.13290.682
21_L25_Q0.132650.681
12_I16_L0.132190.679
83_I135_Q0.13210.678
28_S74_P0.132070.678
51_Q58_Q0.131360.674
149_Q153_M0.131360.674
171_F176_F0.131170.673
109_L173_A0.131130.673
113_D122_I0.130280.669
182_S185_F0.130160.668
125_I165_L0.129840.666
138_S157_L0.129670.666
4_G177_L0.129630.665
127_A165_L0.129460.665
31_K64_H0.129180.663
113_D120_Y0.128070.657
53_M56_E0.1280.657
12_I140_K0.127720.656
49_D53_M0.12670.650
16_L19_L0.126610.650
108_D113_D0.126390.649
188_L191_L0.125990.647
105_W124_P0.12580.646
137_L187_L0.125490.644
73_L77_I0.124810.641
41_E50_Q0.124740.640
28_S71_G0.124380.638
151_K155_I0.124080.637
165_L168_T0.124010.637
28_S66_V0.123860.636
28_S70_K0.123620.635
131_M183_N0.122750.630
137_L160_M0.122730.630
35_L61_Y0.121460.623
108_D124_P0.120890.621
106_F173_A0.120870.620
9_L12_I0.120020.616
168_T171_F0.119970.616
3_W167_F0.119770.615
134_N159_I0.119620.614
86_F171_F0.119360.613
23_I26_Q0.119070.611
128_G135_Q0.118940.611
135_Q138_S0.118760.610
123_L176_F0.118760.610
25_Q36_Q0.118750.610
112_P119_P0.118640.609
128_G131_M0.118450.608
131_M164_F0.118340.607
34_E64_H0.118220.607
60_L68_P0.117850.605
105_W121_F0.117580.604
160_M164_F0.11750.603
120_Y169_S0.117280.602
158_Y162_L0.116880.600
38_E44_E0.116610.599
81_I84_G0.116270.597
163_M168_T0.11620.596
101_G156_M0.115620.593
107_P122_I0.115460.593
47_K53_M0.115310.592
55_Q63_K0.115140.591
11_T128_G0.114730.589
81_I85_L0.114570.588
76_L104_L0.114380.587
24_K177_L0.114080.586
174_A190_T0.1140.585
79_I84_G0.113810.584
22_S26_Q0.113390.582
48_E51_Q0.113260.581
15_R193_L0.113230.581
83_I88_A0.112860.579
111_A122_I0.112570.578
101_G105_W0.112130.576
175_L190_T0.112110.575
61_Y68_P0.112060.575
12_I181_T0.111940.575
155_I158_Y0.111890.574
113_D124_P0.111690.573
96_P106_F0.111420.572
102_G113_D0.111340.572
7_I11_T0.111320.571
133_L137_L0.111090.570
123_L180_I0.110750.568
104_L181_T0.110710.568
96_P185_F0.110480.567
127_A171_F0.110060.565
4_G109_L0.110020.565
94_E108_D0.109650.563
77_I80_P0.109640.563
13_L151_K0.109550.562
3_W170_F0.109520.562
157_L172_P0.109470.562
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3pjsK0.2929310.944
3vouA0.368718.60.95
3hbfA0.40417.50.95
3effK0.3333140.952
3rvyA0.333312.10.953
4h33A0.338410.70.954
2acvA0.4049.50.955
2ksdA0.3038.50.956
2pq6A0.41928.20.957
4djkA0.32327.70.957
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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