GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
SURF1 - SURF1 family
Pfam: PF02104 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 212
Sequences: 1117
Seq/Len: 5.27
HH_delta: 0.951 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
61_S127_T0.476484.540
13_F207_F0.468724.466
12_G207_F0.324343.090
130_G174_L0.266852.543
87_T101_R0.254272.423
9_V210_A0.239242.280
89_F126_V0.239152.279
65_D90_R0.235672.246
54_E133_R0.231012.201
59_T129_T0.228662.179
60_V174_L0.224332.138
16_L207_F0.212752.027
63_R90_R0.212372.024
69_Q87_T0.211742.018
40_L60_V0.210632.007
65_D68_K0.207561.978
65_D96_A0.197341.880
135_P158_L0.194521.853
27_A31_A0.193441.843
19_A23_Q0.19271.836
84_H100_N0.191851.828
59_T127_T0.19071.817
64_F89_F0.186571.778
71_L85_V0.182971.743
58_V174_L0.179541.711
60_V89_F0.177391.690
13_F17_D0.171081.630
17_D21_W0.170451.624
62_G89_F0.161621.540
22_K199_H0.155961.486
199_H209_L0.154071.468
40_L172_F0.153861.466
24_A28_R0.153421.462
5_I9_V0.151121.440
63_R89_F0.148231.412
23_Q27_A0.146711.398
97_V174_L0.144511.377
3_L7_L0.144241.374
100_N175_Q0.14331.365
61_S125_E0.142871.361
18_R22_K0.141941.352
12_G16_L0.141711.350
195_P201_G0.141171.345
63_R124_G0.140721.341
22_K25_L0.140661.340
66_P114_L0.140541.339
201_G205_Q0.13691.304
198_K201_G0.135991.296
39_P59_T0.135821.294
82_G103_W0.134321.280
91_L95_R0.13431.280
208_G212_A0.132691.264
64_F69_Q0.132381.261
92_D125_E0.131691.255
147_D150_P0.128231.222
21_W197_N0.127341.213
64_F176_Q0.126181.202
60_V91_L0.124991.191
140_G143_T0.124731.188
62_G101_R0.123561.177
26_I196_P0.123521.177
195_P205_Q0.12311.173
64_F99_V0.122331.166
202_Y206_W0.121871.161
66_P69_Q0.12161.159
5_I8_L0.120541.149
199_H207_F0.120451.148
129_T177_D0.119441.138
196_P199_H0.119331.137
65_D167_L0.119331.137
12_G25_L0.119131.135
57_R177_D0.119091.135
69_Q114_L0.118561.130
182_A185_P0.117651.121
148_P151_N0.116211.107
55_Y191_P0.114721.093
157_D160_A0.114021.086
53_L56_R0.113071.077
11_L14_W0.112031.067
18_R203_A0.111241.060
53_L86_L0.111181.059
111_R114_L0.10791.028
133_R175_Q0.107551.025
205_Q209_L0.106861.018
73_D205_Q0.106021.010
197_N201_G0.105791.008
69_Q101_R0.105371.004
11_L15_Q0.104790.998
133_R136_E0.103510.986
66_P87_T0.102390.976
4_A7_L0.101630.968
74_N205_Q0.10150.967
83_Y152_R0.101240.965
64_F101_R0.099690.950
90_R96_A0.099260.946
22_K196_P0.098940.943
69_Q85_V0.09860.940
88_P98_L0.097970.934
86_L105_P0.097790.932
9_V13_F0.097180.926
37_P59_T0.096540.920
62_G85_V0.096190.917
19_A200_L0.095980.915
161_M165_L0.095770.913
31_A34_S0.095260.908
19_A199_H0.095010.905
37_P40_L0.0950.905
21_W24_A0.094940.905
154_Q205_Q0.094890.904
101_R124_G0.094850.904
73_D103_W0.09480.903
59_T163_Q0.094440.900
29_I195_P0.094420.900
75_R84_H0.094160.897
7_L96_A0.093950.895
6_A99_V0.093680.893
8_L209_L0.093520.891
199_H202_Y0.0930.886
198_K205_Q0.092610.882
66_P126_V0.092510.881
63_R125_E0.092450.881
201_G208_G0.092160.878
73_D142_F0.091970.876
18_R21_W0.091440.871
197_N205_Q0.091230.869
89_F97_V0.09120.869
72_L75_R0.09120.869
16_L204_L0.091120.868
44_L132_L0.090640.864
85_V184_G0.090450.862
153_W205_Q0.090380.861
55_Y100_N0.090330.861
8_L210_A0.089940.857
85_V104_V0.089770.855
154_Q198_K0.089610.854
209_L212_A0.089580.854
97_V116_E0.089480.853
74_N154_Q0.089270.851
89_F101_R0.089210.850
22_K209_L0.089150.849
95_R99_V0.089060.849
2_L183_A0.088960.848
61_S92_D0.088550.844
12_G22_K0.088420.843
85_V193_V0.088260.841
70_I153_W0.088230.841
107_E179_D0.088150.840
15_Q18_R0.088060.839
89_F128_V0.087650.835
81_P115_P0.08710.830
183_A186_P0.087060.830
37_P129_T0.086940.828
98_L165_L0.086920.828
97_V171_P0.086690.826
175_Q193_V0.086470.824
148_P185_P0.085920.819
54_E134_P0.08520.812
6_A10_G0.085040.810
10_G17_D0.084870.809
146_N155_S0.084250.803
83_Y91_L0.084250.803
175_Q191_P0.084140.802
123_S178_A0.083810.799
20_Q86_L0.083420.795
12_G15_Q0.082990.791
19_A197_N0.082950.790
10_G13_F0.082440.786
160_A174_L0.082310.784
160_A164_A0.082240.784
110_D126_V0.082040.782
103_W157_D0.081960.781
57_R129_T0.081940.781
125_E128_V0.081810.780
37_P163_Q0.081630.778
65_D88_P0.081460.776
53_L132_L0.081430.776
21_W25_L0.081140.773
9_V106_A0.080880.771
83_Y104_V0.080850.770
2_L60_V0.080620.768
20_Q23_Q0.080590.768
43_L56_R0.080570.768
23_Q197_N0.080330.765
75_R103_W0.080080.763
201_G207_F0.080020.762
168_P174_L0.080010.762
176_Q184_G0.079980.762
4_A8_L0.079820.761
199_H205_Q0.079750.760
64_F124_G0.079490.757
96_A167_L0.079460.757
16_L203_A0.079440.757
184_G187_P0.079440.757
19_A73_D0.078990.753
53_L208_G0.078940.752
16_L200_L0.078910.752
6_A9_V0.078810.751
41_P153_W0.078750.750
84_H173_Y0.078710.750
13_F16_L0.078630.749
155_S158_L0.078260.746
203_A207_F0.07820.745
143_T146_N0.077930.743
20_Q137_P0.077830.742
66_P124_G0.077640.740
70_I161_M0.077330.737
52_D93_D0.07730.737
27_A30_E0.077250.736
133_R199_H0.076940.733
21_W189_W0.076850.732
7_L10_G0.076720.731
13_F203_A0.076670.731
158_L162_A0.076660.730
98_L162_A0.076640.730
26_I209_L0.07660.730
56_R195_P0.076490.729
54_E212_A0.076420.728
70_I167_L0.076230.726
31_A79_G0.076190.726
158_L163_Q0.076040.725
95_R170_A0.075810.722
157_D208_G0.075690.721
39_P43_L0.075560.720
64_F192_V0.075520.720
30_E44_L0.075480.719
40_L95_R0.075370.718
57_R130_G0.075280.717
51_E179_D0.074930.714
109_A151_N0.074870.713
9_V172_F0.074870.713
133_R173_Y0.074580.711
71_L111_R0.074410.709
33_L193_V0.074290.708
2_L137_P0.074280.708
201_G212_A0.074140.706
19_A205_Q0.074130.706
56_R128_V0.074120.706
194_M201_G0.074010.705
70_I165_L0.073670.702
8_L196_P0.073580.701
84_H132_L0.073360.699
45_D170_A0.07320.697
8_L156_I0.073010.696
87_T128_V0.072810.694
126_V159_E0.072780.693
55_Y173_Y0.072770.693
80_R105_P0.072770.693
34_S136_E0.072670.692
9_V16_L0.072620.692
86_L100_N0.072570.691
31_A42_D0.072430.690
164_A167_L0.072190.688
39_P168_P0.072120.687
12_G19_A0.07210.687
57_R63_R0.072010.686
70_I155_S0.071980.686
132_L145_E0.071980.686
27_A68_K0.071940.685
2_L6_A0.071940.685
125_E166_G0.07180.684
34_S42_D0.071660.683
114_L185_P0.071640.683
104_V129_T0.071630.683
113_A128_V0.071620.682
141_I155_S0.071390.680
107_E112_A0.071250.679
86_L208_G0.07120.678
173_Y176_Q0.071130.678
58_V129_T0.07110.677
99_V174_L0.071060.677
132_L155_S0.071040.677
77_R82_G0.070940.676
182_A186_P0.070640.673
109_A148_P0.070620.673
26_I195_P0.07060.673
64_F87_T0.070560.672
32_R171_P0.070550.672
29_I156_I0.070480.672
199_H206_W0.070460.671
76_S137_P0.070340.670
113_A124_G0.070160.669
18_R199_H0.070140.668
97_V128_V0.070020.667
78_D157_D0.069790.665
64_F72_L0.069740.665
3_L52_D0.069640.664
94_G132_L0.069590.663
138_R144_P0.069580.663
26_I30_E0.069560.663
115_P205_Q0.069420.661
90_R167_L0.069370.661
31_A52_D0.069220.660
69_Q111_R0.069220.660
168_P171_P0.068750.655
4_A84_H0.06860.654
19_A198_K0.068590.654
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2m67A0.165118.60.951
2lx0A0.103812.30.954
3u66A0.28310.90.955
2k1kA0.08965.70.96
2h3oA0.12264.40.962
2ks1B0.11324.30.962
2jwaA0.11323.60.964
1v54L0.08962.70.966
1wazA0.09432.60.966
2l2tA0.12262.30.967
If you are interested in a protein containing this domain,
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