GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Chromate_transp - Chromate transporter
Pfam: PF02417 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 169
Sequences: 2827
Seq/Len: 16.73
HH_delta: 0.945 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
28_Q40_E0.780884.128
39_T42_E0.62663.313
6_F81_G0.619813.277
29_R33_E0.613913.246
42_E68_R0.51292.712
11_K30_E0.464932.458
63_T79_T0.434252.296
30_E34_R0.429162.269
4_E35_R0.427212.259
67_Y75_A0.364571.927
135_D138_T0.360361.905
2_L77_V0.351291.857
30_E35_R0.34041.800
77_V81_G0.33321.762
28_Q33_E0.3181.681
38_L65_I0.314351.662
147_I152_F0.313441.657
145_A159_V0.311481.647
154_I158_Y0.310641.642
155_N158_Y0.306661.621
6_F84_L0.288721.526
149_L159_V0.28811.523
5_L70_A0.281821.490
3_L7_W0.280681.484
46_G64_F0.278791.474
146_F150_L0.277331.466
7_W11_K0.268861.421
159_V163_G0.266141.407
119_G123_A0.265821.405
160_I167_G0.264851.400
43_F47_L0.262481.388
66_G74_G0.262311.387
20_G23_I0.261931.385
15_F26_L0.258841.368
74_G78_A0.257771.363
88_L92_L0.256211.355
164_A167_G0.251661.330
33_E36_G0.25011.322
124_A128_L0.24991.321
2_L73_L0.2441.290
148_L152_F0.243731.289
140_A144_I0.24231.281
22_A124_A0.241261.275
8_S30_E0.237481.256
27_I62_A0.23571.246
12_I27_I0.234241.238
163_G167_G0.233621.235
76_I80_I0.232671.230
7_W10_F0.228581.208
23_I58_A0.226531.198
8_S12_I0.225291.191
157_I161_L0.224561.187
13_G26_L0.22361.182
5_L78_A0.219831.162
161_L164_A0.218181.153
10_F84_L0.2171.147
158_Y162_I0.212311.122
164_A168_L0.212241.122
29_R34_R0.210051.110
73_L76_I0.208411.102
13_G86_S0.204271.080
148_L162_I0.200971.062
90_I93_L0.200331.059
126_I130_K0.199781.056
100_F103_N0.19971.056
50_A53_L0.197951.047
12_I25_P0.197431.044
31_F65_I0.19711.042
16_S43_F0.196061.037
16_S23_I0.195561.034
104_P108_A0.194121.026
112_G116_A0.192061.015
20_G58_A0.191191.011
105_W109_F0.189651.003
43_F61_L0.189381.001
147_I151_F0.189261.001
10_F88_L0.188490.997
40_E131_K0.18770.992
31_F37_W0.187220.990
47_L61_L0.185410.980
115_P156_P0.183290.969
8_S35_R0.183020.968
21_Y57_I0.182680.966
12_I86_S0.182580.965
137_I166_L0.181330.959
13_G124_A0.180130.952
32_V43_F0.179590.949
24_I43_F0.17920.947
9_F31_F0.178510.944
9_F78_A0.17830.943
162_I166_L0.178080.941
129_A133_I0.177990.941
17_F23_I0.177680.939
101_R107_Q0.177390.938
5_L69_L0.177230.937
162_I165_L0.177210.937
8_S37_W0.176730.934
86_S115_P0.17640.933
140_A143_L0.174280.921
10_F14_L0.173660.918
2_L70_A0.172670.913
123_A126_I0.172460.912
5_L9_F0.172370.911
46_G61_L0.172330.911
11_K15_F0.171660.908
161_L165_L0.171090.905
144_I148_L0.170690.902
14_L89_L0.170420.901
104_P107_Q0.16790.888
64_F68_R0.166390.880
16_S22_A0.166390.880
142_A146_F0.166260.879
28_Q127_K0.165150.873
136_W140_A0.16450.870
9_F13_G0.164150.868
136_W139_I0.164110.868
124_A156_P0.162190.857
48_A160_I0.162060.857
155_N159_V0.161920.856
22_A58_A0.159420.843
17_F113_V0.159290.842
59_I79_T0.157920.835
44_L113_V0.15770.834
69_L73_L0.157120.831
43_F120_L0.156680.828
134_K139_I0.156210.826
98_S102_E0.155150.820
93_L96_L0.155140.820
5_L77_V0.155080.820
24_I47_L0.154740.818
148_L159_V0.153840.813
134_K138_T0.153790.813
123_A127_K0.153770.813
12_I53_L0.153760.813
24_I51_Q0.153490.811
70_A74_G0.152930.809
31_F38_L0.15270.807
27_I58_A0.152530.806
5_L74_G0.152210.805
23_I57_I0.15170.802
57_I61_L0.151670.802
25_P63_T0.151180.799
59_I86_S0.150450.795
16_S47_L0.150230.794
21_Y24_I0.149970.793
59_I83_I0.14980.792
41_E139_I0.149610.791
90_I94_S0.148420.785
84_L88_L0.148210.784
73_L77_V0.148070.783
133_I139_I0.147880.782
54_P66_G0.147730.781
22_A94_S0.14720.778
122_L141_I0.147060.777
141_I145_A0.146740.776
63_T75_A0.146670.775
99_R102_E0.146670.775
156_P160_I0.146610.775
57_I117_V0.146520.775
79_T83_I0.146060.772
20_G57_I0.145370.769
24_I61_L0.14530.768
9_F22_A0.144720.765
52_A61_L0.14460.764
6_F9_F0.144320.763
161_L168_L0.143810.760
47_L52_A0.142810.755
57_I62_A0.14280.755
62_A82_F0.142280.752
20_G61_L0.141930.750
6_F77_V0.141780.750
146_F152_F0.141530.748
134_K137_I0.141490.748
157_I164_A0.141440.748
139_I143_L0.140890.745
99_R151_F0.140870.745
119_G153_K0.140830.745
23_I90_I0.140010.740
100_F106_V0.139440.737
99_R153_K0.139040.735
77_V80_I0.138850.734
59_I62_A0.138590.733
16_S21_Y0.138080.730
137_I140_A0.137980.729
50_A83_I0.137730.728
93_L100_F0.137210.725
20_G82_F0.137020.724
53_L57_I0.136850.724
103_N107_Q0.136620.722
137_I144_I0.136450.721
3_L154_I0.136340.721
130_K133_I0.13630.721
116_A119_G0.136150.720
58_A82_F0.135860.718
154_I159_V0.135720.718
108_A165_L0.135650.717
84_L87_F0.135380.716
22_A82_F0.134760.712
53_L63_T0.134430.711
96_L135_D0.1340.708
53_L75_A0.133680.707
31_F104_P0.132650.701
107_Q111_K0.132620.701
108_A112_G0.132470.700
16_S58_A0.13220.699
81_G120_L0.131960.698
53_L59_I0.131930.697
25_P51_Q0.131590.696
48_A67_Y0.131580.696
94_S113_V0.13150.695
42_E45_E0.131450.695
78_A81_G0.131330.694
31_F35_R0.131310.694
147_I150_L0.131260.694
2_L5_L0.131110.693
12_I23_I0.130940.692
121_I128_L0.130880.692
28_Q43_F0.130860.692
138_T145_A0.130750.691
36_G73_L0.130260.689
72_F75_A0.129410.684
102_E105_W0.129190.683
115_P119_G0.128810.681
3_L151_F0.128760.681
26_L120_L0.128220.678
16_S19_G0.128170.678
95_P98_S0.127890.676
29_R160_I0.127720.675
53_L79_T0.127490.674
41_E131_K0.127350.673
58_A83_I0.127320.673
84_L120_L0.127280.673
75_A78_A0.127220.673
74_G81_G0.127090.672
158_Y161_L0.127050.672
121_I124_A0.126090.667
13_G53_L0.12480.660
33_E40_E0.124480.658
125_A129_A0.124320.657
74_G146_F0.1240.656
102_E107_Q0.123660.654
23_I120_L0.123610.654
6_F75_A0.123480.653
5_L66_G0.123050.651
46_G59_I0.122590.648
49_L68_R0.122270.646
14_L88_L0.122050.645
13_G30_E0.121930.645
58_A119_G0.121930.645
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2h3oA0.360910.50.945
2e1zA0.36696.40.95
2m67A0.47935.60.951
2l8sA0.124340.954
2wyaA0.53253.50.955
3k3fA0.76332.70.958
2kncA0.1422.60.958
1afoA0.23672.40.959
2f82A0.49112.10.96
3s0xA0.39641.90.961
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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