GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Tim17 - Tim17Tim22Tim23Pmp24 family
Pfam: PF02466 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 128
Sequences: 1041
Seq/Len: 8.13
HH_delta: 0.906 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
92_A111_A0.524614.470
79_R83_D0.381693.252
75_L89_I0.292632.494
96_A111_A0.236782.018
79_R86_N0.217941.857
83_D86_N0.21121.800
75_L90_A0.210451.793
114_G117_F0.187521.598
109_S112_A0.184281.570
43_L46_I0.180741.540
88_A115_A0.178691.523
67_L71_I0.171581.462
103_G106_G0.166791.421
4_E10_T0.165371.409
87_S122_E0.162021.381
92_A115_A0.158191.348
11_G14_F0.155951.329
16_A19_V0.145821.243
33_P36_G0.144221.229
67_L89_I0.144071.228
104_P107_M0.143221.220
70_G74_A0.141011.202
91_G95_G0.140791.200
65_G69_S0.140261.195
85_W89_I0.1391.184
12_K16_A0.138241.178
94_A114_G0.1371.167
108_A112_A0.136741.165
35_R38_P0.135631.156
75_L124_Y0.131071.117
103_G110_G0.130991.116
76_E82_D0.13061.113
8_D12_K0.129121.100
44_R48_N0.129111.100
5_R13_G0.128291.093
10_T66_G0.128211.093
97_V100_L0.127711.088
5_R72_E0.126891.081
3_P6_I0.12591.073
42_R45_S0.125461.069
117_F124_Y0.125071.066
9_S69_S0.124311.059
61_F69_S0.124091.057
119_A123_Y0.122931.048
106_G110_G0.122691.045
81_K121_V0.121581.036
9_S13_G0.120891.030
47_L117_F0.120521.027
26_A50_V0.120091.023
43_L47_L0.120031.023
34_P37_S0.11991.022
20_F24_I0.119721.020
71_I93_A0.119161.015
68_Y91_G0.119121.015
39_L43_L0.118941.014
33_P37_S0.118381.009
68_Y119_A0.118051.006
44_R80_G0.117611.002
10_T62_G0.116940.996
88_A119_A0.116230.990
4_E7_L0.115840.987
69_S72_E0.115240.982
12_K49_A0.114290.974
23_F27_I0.113890.970
48_N52_R0.113820.970
109_S113_L0.113440.967
118_A122_E0.112610.960
114_G118_A0.112070.955
32_R35_R0.111990.954
5_R8_D0.111530.950
47_L63_S0.111010.946
18_A58_G0.110450.941
50_V57_H0.110.937
92_A108_A0.109540.933
63_S67_L0.109140.930
85_W115_A0.109010.929
68_Y100_L0.108360.923
8_D11_G0.107910.920
44_R47_L0.107750.918
102_S106_G0.107460.916
3_P74_A0.107070.912
36_G40_R0.106250.905
73_C87_S0.106220.905
63_S79_R0.105930.903
25_G57_H0.105840.902
4_E11_G0.105010.895
46_I49_A0.104460.890
84_P88_A0.104060.887
116_A120_A0.103750.884
46_I84_P0.103480.882
69_S94_A0.103420.881
18_A51_G0.103290.880
45_S52_R0.103250.880
111_A115_A0.103150.879
38_P78_L0.102770.876
46_I50_V0.10270.875
87_S102_S0.102660.875
90_A94_A0.102450.873
78_L100_L0.101960.869
9_S16_A0.10190.868
4_E12_K0.101810.868
59_A103_G0.101320.863
91_G98_L0.100990.861
70_G98_L0.100680.858
13_G94_A0.100650.858
19_V97_V0.10040.856
74_A78_L0.100260.854
116_A121_V0.100060.853
63_S66_G0.100010.852
94_A103_G0.099860.851
29_A58_G0.09950.848
88_A99_G0.099290.846
101_R107_M0.099130.845
11_G15_V0.098820.842
19_V85_W0.098640.841
22_G26_A0.097950.835
93_A102_S0.097640.832
92_A107_M0.097530.831
110_G114_G0.097460.830
118_A121_V0.097150.828
76_E86_N0.096840.825
24_I28_S0.096210.820
4_E8_D0.096110.819
103_G107_M0.095680.815
42_R48_N0.095460.813
3_P14_F0.095360.813
9_S82_D0.095250.812
38_P41_P0.095060.810
66_G93_A0.094940.809
116_A122_E0.094660.807
60_R80_G0.093860.800
65_G80_G0.09380.799
88_A92_A0.092660.790
78_L116_A0.092110.785
21_G25_G0.091390.779
14_F58_G0.09110.776
62_G66_G0.090580.772
32_R58_G0.090340.770
112_A119_A0.090320.770
22_G112_A0.090250.769
15_V48_N0.090020.767
82_D101_R0.089750.765
41_P48_N0.089750.765
25_G49_A0.089560.763
10_T113_L0.089440.762
68_Y97_V0.088910.758
74_A77_R0.08890.758
66_G84_P0.088870.757
4_E89_I0.088850.757
48_N97_V0.088840.757
70_G77_R0.088590.755
21_G29_A0.088260.752
96_A110_G0.088050.750
62_G77_R0.088030.750
20_F76_E0.087870.749
8_D100_L0.08740.745
46_I108_A0.087370.745
5_R77_R0.087190.743
23_F81_K0.086980.741
39_L116_A0.086230.735
22_G50_V0.086180.734
89_I123_Y0.086020.733
67_L94_A0.0860.733
113_L117_F0.085750.731
65_G101_R0.085370.727
65_G98_L0.085320.727
11_G89_I0.085320.727
75_L93_A0.085180.726
74_A99_G0.085050.725
18_A23_F0.08470.722
24_I124_Y0.084650.721
23_F50_V0.084360.719
38_P62_G0.084320.719
14_F66_G0.084250.718
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2lckA0.960912.90.906
1kvdA0.35946.90.916
2ls2A0.20315.40.92
4fc4A0.49224.80.922
3tdsE0.54694.70.922
4hygA0.687540.925
4bduA0.52342.80.93
3hfwA0.52.70.93
2kxaA0.23442.20.933
1okcA12.20.933
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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