GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Rnf-Nqr - Rnf-Nqr subunit membrane protein
Pfam: PF02508 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 190
Sequences: 1402
Seq/Len: 7.38
HH_delta: 0.955 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
27_P142_F0.546023.625
42_G143_T0.52473.483
8_F137_G0.465613.091
50_T136_L0.464623.084
54_V132_L0.434642.885
90_L94_F0.41472.753
10_S15_N0.399162.650
54_V128_F0.387672.573
127_S130_E0.381132.530
46_T143_T0.378832.515
60_R71_R0.312362.074
19_L145_A0.308072.045
35_L147_V0.282451.875
51_L82_L0.280061.859
4_F133_V0.272181.807
50_T135_G0.269841.791
163_E166_R0.268411.782
54_V58_L0.261811.738
87_E98_Y0.257681.711
9_I14_V0.248651.651
50_T132_L0.245681.631
152_I184_G0.235741.565
52_S82_L0.234021.553
85_L89_V0.233221.548
58_L128_F0.230561.531
52_S118_A0.221731.472
17_P138_A0.218031.447
126_Y131_S0.20971.392
46_T140_L0.207381.377
40_G97_L0.203531.351
149_L175_A0.202421.344
143_T147_V0.198531.318
32_S146_L0.198321.316
38_A42_G0.197731.313
48_V108_I0.197291.310
58_L62_F0.197071.308
35_L150_A0.196391.304
45_V143_T0.195731.299
44_A79_I0.19431.290
149_L184_G0.19081.267
151_G161_I0.189741.260
4_F129_L0.189331.257
121_F134_D0.187961.248
23_L116_G0.18751.245
151_G155_R0.186591.239
59_L63_I0.179541.192
5_F127_S0.177111.176
53_S121_F0.177111.176
7_I133_V0.176331.171
91_R98_Y0.171971.142
39_L147_V0.171491.138
49_L139_G0.171081.136
71_R75_F0.170571.132
181_A184_G0.171.128
53_S135_G0.169011.122
17_P21_Q0.165431.098
186_G189_I0.165421.098
44_A90_L0.165421.098
43_L47_F0.164981.095
25_L185_F0.16491.095
79_I118_A0.164551.092
58_L61_N0.164181.090
89_V93_Y0.163221.083
71_R122_A0.161761.074
76_I115_L0.161151.070
21_Q70_L0.160831.068
165_F170_I0.160351.064
8_F133_V0.160311.064
20_V161_I0.160251.064
15_N21_Q0.159761.061
162_P187_G0.159091.056
34_S37_N0.159021.056
11_A134_D0.158141.050
7_I130_E0.158121.050
5_F9_I0.157251.044
131_S135_G0.155381.031
17_P24_G0.154451.025
10_S14_V0.153931.022
27_P45_V0.153921.022
38_A143_T0.153351.018
11_A138_A0.152671.013
148_L152_I0.152441.012
108_I112_C0.151711.007
48_V86_V0.150230.997
35_L38_A0.149790.994
95_P99_K0.149680.994
43_L46_T0.148220.984
75_F82_L0.147370.978
71_R119_E0.146520.973
12_I144_L0.146210.971
7_I10_S0.146210.971
50_T115_L0.145550.966
74_V115_L0.144590.960
145_A188_L0.143570.953
6_S186_G0.142890.949
93_Y96_S0.142590.947
144_L187_G0.142480.946
6_S14_V0.141470.939
113_A116_G0.14050.933
32_S38_A0.140370.932
51_L54_V0.140.929
53_S131_S0.139930.929
17_P49_L0.139790.928
49_L116_G0.139610.927
63_I163_E0.138910.922
169_P173_I0.138390.919
152_I174_P0.137690.914
44_A104_Y0.137560.913
145_A149_L0.13750.913
156_L159_G0.135890.902
105_L109_T0.135730.901
99_K123_S0.135650.900
101_L106_P0.135170.897
121_F126_Y0.135120.897
155_R158_S0.134590.893
44_A80_A0.134540.893
39_L143_T0.134430.892
96_S100_A0.133690.887
117_R134_D0.132740.881
84_Q88_M0.131940.876
60_R122_A0.131760.875
25_L29_L0.131690.874
13_F19_L0.131470.873
58_L132_L0.13130.872
26_C83_V0.131250.871
4_F130_E0.130730.868
55_L78_V0.129480.860
24_G111_N0.129410.859
59_L78_V0.129330.859
17_P113_A0.129110.857
18_V28_F0.128460.853
59_L74_V0.128210.851
155_R161_I0.128210.851
72_I115_L0.128160.851
86_V100_A0.128030.850
87_E91_R0.127820.848
8_F173_I0.127820.848
6_S12_I0.127290.845
108_I111_N0.12560.834
130_E133_V0.125070.830
7_I138_A0.124850.829
146_L175_A0.124560.827
127_S132_L0.123680.821
126_Y130_E0.12290.816
136_L140_L0.122850.816
21_Q124_K0.122750.815
59_L62_F0.122260.812
100_A114_V0.12180.809
128_F132_L0.121140.804
87_E103_I0.120640.801
85_L88_M0.120390.799
6_S10_S0.120290.799
24_G113_A0.120160.798
120_F134_D0.12010.797
25_L176_G0.120070.797
183_F186_G0.120020.797
156_L171_A0.119210.791
61_N68_S0.118790.789
44_A111_N0.118440.786
79_I108_I0.118380.786
52_S119_E0.118330.786
21_Q138_A0.118190.785
46_T139_G0.117990.783
170_I183_F0.117950.783
4_F8_F0.117320.779
24_G106_P0.117170.778
176_G181_A0.11690.776
148_L188_L0.116660.774
55_L58_L0.115980.770
59_L90_L0.115720.768
43_L157_G0.115690.768
155_R170_I0.11540.766
14_V78_V0.114510.760
8_F61_N0.114350.759
102_G106_P0.11390.756
91_R95_P0.113640.754
18_V99_K0.113590.754
24_G101_L0.113250.752
53_S117_R0.113220.752
26_C112_C0.113180.751
44_A108_I0.113060.751
18_V41_M0.112750.748
123_S188_L0.112740.748
129_L132_L0.112680.748
21_Q110_V0.112660.748
106_P109_T0.112240.745
86_V145_A0.112120.744
184_G187_G0.111770.742
101_L116_G0.111710.742
82_L85_L0.111660.741
53_S56_I0.111610.741
59_L162_P0.110660.735
16_N141_G0.109630.728
63_I98_Y0.109580.727
11_A137_G0.109550.727
164_S169_P0.109510.727
127_S131_S0.109360.726
115_L119_E0.108780.722
56_I78_V0.108580.721
77_L184_G0.10840.720
18_V85_L0.108290.719
24_G112_C0.107930.716
127_S162_P0.107890.716
161_I170_I0.107750.715
169_P172_L0.107740.715
61_N96_S0.10740.713
12_I159_G0.107240.712
136_L156_L0.107020.710
88_M135_G0.106950.710
114_V117_R0.106740.709
101_L118_A0.106690.708
72_I75_F0.106530.707
28_F149_L0.106440.707
98_Y104_Y0.106310.706
140_L144_L0.10630.706
18_V25_L0.106250.705
89_V94_F0.106110.704
72_I119_E0.1060.704
40_G89_V0.105960.703
147_V151_G0.105920.703
13_F185_F0.105730.702
117_R138_A0.105680.702
52_S78_V0.10560.701
41_M83_V0.105590.701
7_I167_G0.105440.700
149_L189_I0.105370.699
12_I42_G0.105140.698
58_L135_G0.105090.698
135_G148_L0.104980.697
110_V114_V0.104670.695
20_V86_V0.104370.693
44_A149_L0.104090.691
184_G188_L0.103990.690
40_G109_T0.103840.689
10_S188_L0.103810.689
39_L160_T0.10370.688
144_L147_V0.103610.688
76_I102_G0.103560.687
22_F189_I0.103430.687
117_R175_A0.103390.686
6_S140_L0.103310.686
162_P167_G0.103120.685
152_I172_L0.10310.684
41_M47_F0.103090.684
142_F146_L0.102930.683
9_I130_E0.102890.683
6_S9_I0.102840.683
49_L53_S0.102720.682
49_L118_A0.102650.681
42_G45_V0.10260.681
33_T185_F0.102530.681
25_L110_V0.102530.681
8_F12_I0.10250.680
51_L132_L0.102180.678
26_C32_S0.101960.677
27_P146_L0.101860.676
7_I121_F0.101720.675
9_I58_L0.10160.674
31_V37_N0.101580.674
61_N132_L0.101540.674
86_V115_L0.101480.674
48_V83_V0.101280.672
59_L124_K0.101270.672
50_T55_L0.100950.670
131_S134_D0.100950.670
33_T168_L0.100660.668
134_D157_G0.100560.668
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3zuxA0.973710.80.955
3ixzA0.53686.20.96
4ddjA0.14744.60.962
1lnqA0.46323.20.964
2ls2A0.13682.20.967
3rfuA0.310520.968
2zxeA0.52631.60.97
2ls3A0.15261.40.97
1mswD0.27891.40.97
3l6iA0.31051.40.971
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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