GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Abi - CAAX protease self-immunity
Pfam: PF02517 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0472
Length: 91
Sequences: 5199
Seq/Len: 57.13
HH_delta: 0.906 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
40_I69_G1.464093.002
64_F68_F1.240152.543
48_A62_F1.222282.506
27_F73_L1.053252.159
16_I82_I1.019872.091
22_F50_W1.019372.090
15_P86_A1.014322.080
70_Y74_R0.974541.998
27_F69_G0.940211.928
48_A61_A0.82761.697
72_Y81_A0.815881.673
31_R73_L0.803481.647
44_S48_A0.747471.532
36_P73_L0.726971.490
27_F39_A0.722791.482
68_F84_A0.716051.468
71_L84_A0.715461.467
44_S69_G0.705251.446
19_E23_R0.703131.442
11_I90_L0.667361.368
35_N38_F0.665021.363
51_H85_H0.66151.356
78_L82_I0.64951.332
18_E51_H0.647191.327
25_F29_R0.631531.295
27_F43_S0.617991.267
43_S69_G0.604041.238
51_H89_N0.598311.227
30_L42_I0.578031.185
45_L62_F0.569171.167
40_I73_L0.564511.157
47_F51_H0.562981.154
44_S66_L0.562311.153
23_R65_G0.560961.150
44_S62_F0.548611.125
86_A90_L0.544591.117
15_P89_N0.543411.114
47_F89_N0.530641.088
75_T80_A0.527281.081
48_A65_G0.527141.081
40_I66_L0.525851.078
34_F38_F0.513771.053
35_N39_A0.512751.051
14_A89_N0.509371.044
77_S80_A0.505181.036
11_I15_P0.497261.019
29_R32_R0.4971.019
22_F47_F0.492931.011
18_E89_N0.481050.986
65_G69_G0.4790.982
24_G78_L0.477950.980
83_I87_L0.477230.978
43_S65_G0.475960.976
71_L80_A0.470230.964
27_F72_Y0.466970.957
47_F50_W0.458650.940
12_L15_P0.45520.933
79_W82_I0.447450.917
82_I86_A0.443370.909
58_F61_A0.441030.904
71_L81_A0.436970.896
27_F31_R0.435470.893
48_A58_F0.426420.874
41_L66_L0.426220.874
57_Q60_Y0.413530.848
14_A17_A0.405270.831
28_N31_R0.399540.819
30_L39_A0.394770.809
80_A83_I0.392290.804
53_P57_Q0.39220.804
37_W41_L0.391520.803
26_L43_S0.389010.798
38_F42_I0.386140.792
33_R36_P0.381590.782
12_L86_A0.380420.780
36_P40_I0.367890.754
79_W83_I0.36160.741
45_L49_L0.357670.733
59_I62_F0.356560.731
26_L46_L0.348970.715
31_R35_N0.348450.714
85_H89_N0.348090.714
31_R36_P0.34780.713
72_Y77_S0.343960.705
78_L81_A0.341470.700
40_I43_S0.339660.696
59_I63_L0.334070.685
72_Y76_G0.333990.685
70_Y73_L0.331480.680
15_P82_I0.331390.679
18_E85_H0.329260.675
28_N72_Y0.329150.675
39_A43_S0.329120.675
38_F41_L0.328810.674
21_F25_F0.320180.656
64_F88_W0.318670.653
31_R76_G0.314860.646
77_S81_A0.31240.640
40_I44_S0.310510.637
68_F81_A0.307730.631
37_W70_Y0.307440.630
17_A88_W0.304990.625
24_G72_Y0.304280.624
39_A73_L0.304270.624
72_Y75_T0.304060.623
60_Y63_L0.303980.623
61_A65_G0.301760.619
37_W40_I0.301170.617
31_R39_A0.299390.614
44_S65_G0.298270.612
21_F47_F0.294690.604
73_L76_G0.293520.602
29_R33_R0.293010.601
18_E47_F0.292510.600
10_M13_I0.289240.593
80_A84_A0.287370.589
69_G73_L0.287350.589
39_A69_G0.286910.588
48_A63_L0.283950.582
34_F39_A0.283770.582
17_A20_L0.281540.577
11_I14_A0.280350.575
20_L82_I0.277160.568
62_F66_L0.277020.568
47_F85_H0.276460.567
54_N60_Y0.275510.565
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2bs2C0.80221.80.906
2cb2A0.41761.60.908
3dl8C0.71431.20.914
3ar4A0.340710.917
1afoA0.36260.90.919
2ls4A0.28570.80.921
4gc0A10.80.921
2kssA0.34070.80.922
3klyA10.80.923
2ksfA0.70330.80.923
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

Page generated in 0.0228 seconds.