GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
CRCB - CrcB-like protein
Pfam: PF02537 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0184
Length: 117
Sequences: 2450
Seq/Len: 20.94
HH_delta: 0.922 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
40_G76_T1.61855.172
39_L75_L1.427724.562
44_L68_G0.991173.167
100_Y104_S0.866752.770
38_V111_A0.860312.749
8_G12_A0.851962.723
5_A9_A0.848052.710
38_V107_L0.836642.674
7_G66_F0.772042.467
9_A74_G0.739982.365
14_L71_F0.682812.182
18_L36_V0.617791.974
36_V75_L0.61751.973
10_L71_F0.584531.868
43_L72_C0.574971.837
10_L66_F0.57261.830
85_T100_Y0.55391.770
41_C108_G0.553481.769
85_T97_A0.537071.716
34_L38_V0.528421.689
85_T101_V0.506781.619
12_A74_G0.50631.618
32_G36_V0.48821.560
33_T84_E0.486461.555
49_G116_Y0.432231.381
16_Y20_K0.428451.369
47_L67_L0.424021.355
80_T84_E0.421681.348
44_L72_C0.419891.342
42_F115_G0.416661.331
13_L17_G0.411661.316
44_L74_G0.400731.281
34_L103_V0.399781.278
44_L112_A0.395291.263
47_L68_G0.394811.262
29_F34_L0.377741.207
98_L102_L0.373691.194
30_P88_L0.362821.159
14_L75_L0.348571.114
81_F101_V0.337311.078
66_F71_F0.336521.075
46_L50_L0.336171.074
87_Q90_E0.324091.036
42_F49_G0.32231.030
11_G15_R0.312490.999
6_L9_A0.312140.997
89_F97_A0.311090.994
33_T77_T0.30810.985
20_K24_R0.307930.984
17_G20_K0.305070.975
63_L67_L0.294240.940
17_G21_L0.29370.939
82_I105_V0.292790.936
23_N32_G0.289270.924
42_F111_A0.287470.919
19_S33_T0.283450.906
29_F88_L0.282930.904
82_I86_F0.282560.903
65_L69_T0.280750.897
5_A13_L0.27870.891
104_S108_G0.27860.890
4_V7_G0.276630.884
9_A13_L0.273080.873
12_A72_C0.272740.872
36_V39_L0.27020.863
35_L39_L0.270070.863
102_L106_I0.264910.847
94_W98_L0.264430.845
81_F105_V0.259290.829
83_L87_Q0.258450.826
19_S84_E0.257460.823
4_V65_L0.25430.813
21_L24_R0.253920.811
71_F74_G0.253290.809
93_R96_R0.250640.801
74_G81_F0.249960.799
48_A83_L0.248050.793
86_F112_A0.245990.786
112_A115_G0.243990.780
7_G81_F0.243240.777
19_S36_V0.242280.774
34_L107_L0.239130.764
45_G49_G0.238890.763
103_V106_I0.23450.749
9_A12_A0.234360.749
103_V107_L0.233290.746
84_E87_Q0.231980.741
89_F94_W0.231740.741
46_L49_G0.23090.738
44_L83_L0.230550.737
45_G112_A0.230430.736
68_G83_L0.230360.736
106_I110_L0.230060.735
107_L111_A0.229320.733
88_L100_Y0.227490.727
3_L62_S0.226610.724
95_F99_L0.226130.723
110_L114_L0.225270.720
22_L35_L0.223190.713
109_L112_A0.219220.701
81_F108_G0.219060.700
87_Q91_S0.215760.689
95_F98_L0.212760.680
60_S63_L0.21240.679
75_L81_F0.210640.673
10_L14_L0.20850.666
18_L75_L0.20730.662
36_V88_L0.207270.662
30_P100_Y0.206390.660
78_F82_I0.205180.656
7_G65_L0.20410.652
99_L103_V0.203880.652
112_A116_Y0.203120.649
63_L66_F0.202940.649
51_L63_L0.200210.640
101_V109_L0.20010.639
82_I85_T0.198390.634
62_S66_F0.197350.631
18_L35_L0.196790.629
59_W110_L0.196140.627
13_L74_G0.195720.625
61_P65_L0.195350.624
36_V78_F0.195140.624
97_A105_V0.195080.623
113_W116_Y0.193410.618
42_F114_L0.1930.617
38_V108_G0.191230.611
24_R27_G0.189440.605
97_A101_V0.18890.604
7_G71_F0.188660.603
21_L25_R0.188260.602
72_C75_L0.188020.601
69_T78_F0.186110.595
48_A68_G0.182760.584
74_G78_F0.180.575
38_V41_C0.179830.575
86_F116_Y0.179090.572
22_L25_R0.177340.567
5_A8_G0.177150.566
83_L114_L0.174720.558
8_G13_L0.174370.557
27_G31_W0.173130.553
19_S80_T0.172860.552
22_L89_F0.172830.552
94_W110_L0.172330.551
68_G80_T0.172140.550
41_C67_L0.171990.550
90_E105_V0.171870.549
22_L32_G0.171830.549
62_S65_L0.171790.549
18_L22_L0.171630.548
96_R103_V0.171510.548
68_G112_A0.171310.547
65_L68_G0.171060.547
59_W62_S0.17060.545
43_L47_L0.170250.544
83_L91_S0.169990.543
82_I90_E0.169920.543
50_L58_K0.169180.541
100_Y108_G0.167820.536
91_S96_R0.167610.536
94_W107_L0.167550.535
84_E88_L0.167530.535
38_V42_F0.167520.535
3_L57_S0.165920.530
44_L108_G0.165520.529
23_N27_G0.165230.528
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4apsA0.94026.50.922
4j05A0.931660.923
2a65A0.95735.30.924
3tdsE0.50434.90.925
3j1zP0.95733.60.93
4jr9A0.95733.40.931
1j4nA0.97442.90.933
4fc4A0.50432.80.934
2c0jB0.35042.60.935
1pw4A0.93162.60.935
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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