GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF165 - Uncharacterized ACR YhhQ family COG1738
Pfam: PF02592 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 145
Sequences: 785
Seq/Len: 5.41
HH_delta: 0.942 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
76_I123_I0.340832.787
15_D108_S0.293522.400
84_L115_I0.270332.210
17_I29_A0.262572.147
81_S112_S0.254332.079
114_L142_Y0.248282.030
129_F137_I0.206571.689
100_S103_L0.202691.657
114_L118_V0.201941.651
31_W83_L0.195551.599
7_F81_S0.194961.594
134_I138_I0.190111.554
69_R125_F0.187361.532
84_L111_I0.184361.507
76_I119_I0.180271.474
88_I92_L0.176471.443
130_P133_Q0.176381.442
33_G78_F0.176011.439
57_Q61_E0.175551.435
117_T145_K0.17521.432
85_D112_S0.172581.411
91_K94_R0.172121.407
73_A123_I0.171751.404
70_I74_S0.169551.386
82_Q89_F0.16921.383
85_D89_F0.167091.366
74_S116_D0.16521.351
87_Y91_K0.163871.340
80_I115_I0.16361.338
119_I123_I0.16131.319
120_F124_A0.161281.319
101_L105_N0.157841.291
76_I80_I0.156991.284
82_Q86_V0.155331.270
4_V141_Q0.15531.270
72_L76_I0.153791.257
7_F74_S0.152541.247
1_T141_Q0.151751.241
42_L111_I0.150731.232
59_A62_S0.150551.231
19_E93_K0.150271.229
14_T85_D0.146921.201
19_E101_L0.145731.192
78_F144_V0.145441.189
110_A142_Y0.144451.181
72_L100_S0.143271.171
31_W35_L0.143051.170
69_R127_G0.142721.167
80_I119_I0.141371.156
82_Q117_T0.141041.153
25_A28_K0.140611.150
15_D85_D0.139221.138
1_T56_W0.137471.124
48_I61_E0.136811.119
88_I111_I0.135751.110
19_E104_R0.13411.096
9_L39_L0.13291.087
21_Y29_A0.132581.084
3_G12_L0.132121.080
30_I86_V0.131481.075
126_Y134_I0.131051.072
84_L88_I0.130441.067
89_F112_S0.129471.059
116_D120_F0.128811.053
70_I124_A0.128071.047
77_A119_I0.127021.039
68_P72_L0.126971.038
91_K99_R0.125831.029
91_K95_K0.125651.027
24_K28_K0.125091.023
106_N109_T0.124961.022
3_G37_N0.124781.020
118_V138_I0.123491.010
23_K86_V0.123141.007
11_F15_D0.12291.005
70_I120_F0.122721.003
1_T121_I0.122451.001
123_I127_G0.121580.994
106_N112_S0.121260.991
38_L75_L0.121210.991
1_T137_I0.12030.984
58_E61_E0.12020.983
93_K104_R0.120020.981
3_G82_Q0.11990.980
85_D108_S0.117780.963
81_S105_N0.116520.953
24_K72_L0.116090.949
7_F11_F0.115680.946
2_A50_L0.115650.946
103_L126_Y0.114810.939
14_T86_V0.114460.936
23_K90_S0.11430.935
47_V60_F0.113510.928
18_S90_S0.112950.924
114_L135_L0.112630.921
12_L81_S0.11120.909
119_I139_L0.110780.906
2_A47_V0.110620.904
99_R143_L0.109940.899
120_F125_F0.109710.897
102_W142_Y0.108810.890
5_L61_E0.108780.889
48_I57_Q0.108730.889
116_D145_K0.108310.886
82_Q85_D0.107950.883
137_I141_Q0.107450.879
20_V112_S0.107010.875
2_A141_Q0.106510.871
33_G113_Q0.106130.868
12_L109_T0.106120.868
82_Q105_N0.105620.864
24_K135_L0.10550.863
59_A65_G0.105390.862
49_L54_P0.104830.857
86_V89_F0.10440.854
20_V32_I0.104160.852
12_L105_N0.104080.851
102_W105_N0.10380.849
131_F134_I0.103780.849
23_K85_D0.103510.846
139_L143_L0.103440.846
18_S105_N0.103230.844
27_R91_K0.103160.843
48_I64_F0.103070.843
44_I64_F0.102910.841
61_E132_D0.10290.841
131_F138_I0.10260.839
83_L94_R0.102570.839
7_F78_F0.102460.838
22_G79_L0.102370.837
14_T82_Q0.101020.826
122_T126_Y0.100620.823
14_T89_F0.100460.821
129_F133_Q0.10.818
52_P57_Q0.099810.816
126_Y131_F0.099590.814
3_G26_A0.099320.812
11_F95_K0.099140.811
17_I21_Y0.099040.810
11_F109_T0.098590.806
83_L107_G0.098530.806
55_F117_T0.098160.803
3_G15_D0.097970.801
54_P133_Q0.097670.799
1_T4_V0.097570.798
34_F79_L0.097490.797
8_P81_S0.097420.797
80_I135_L0.097420.797
80_I139_L0.097380.796
37_N74_S0.097020.793
117_T142_Y0.096160.786
14_T112_S0.096060.785
121_I141_Q0.096050.785
90_S112_S0.095960.785
107_G143_L0.095950.785
17_I20_V0.095940.784
16_I20_V0.095940.784
133_Q136_S0.095830.784
21_Y101_L0.095630.782
10_T33_G0.095360.780
35_L143_L0.095260.779
23_K27_R0.095120.778
61_E65_G0.094990.777
31_W79_L0.094970.777
76_I139_L0.094810.775
23_K87_Y0.094240.771
18_S73_A0.094190.770
103_L113_Q0.093870.768
58_E94_R0.093770.767
84_L87_Y0.093770.767
42_L45_W0.093760.767
74_S120_F0.093590.765
73_A116_D0.093590.765
15_D109_T0.093470.764
24_K143_L0.093430.764
26_A86_V0.09340.764
85_D106_N0.092960.760
12_L74_S0.092850.759
3_G109_T0.092810.759
10_T92_L0.09260.757
117_T141_Q0.092540.757
19_E113_Q0.092420.756
78_F116_D0.091920.752
121_I138_I0.091850.751
38_L41_S0.091850.751
7_F105_N0.091640.749
19_E105_N0.091610.749
89_F105_N0.091590.749
58_E62_S0.09140.747
84_L123_I0.091290.746
107_G114_L0.091160.745
79_L114_L0.091030.744
1_T6_I0.091010.744
92_L144_V0.090780.742
86_V100_S0.090630.741
77_A89_F0.090620.741
21_Y31_W0.090570.741
5_L140_G0.090250.738
104_R113_Q0.090170.737
49_L65_G0.090020.736
102_W106_N0.089910.735
41_S67_T0.089450.731
34_F116_D0.089110.729
46_I60_F0.089090.728
48_I60_F0.089040.728
58_E99_R0.088840.726
119_I127_G0.088510.724
5_L142_Y0.088150.721
9_L12_L0.087780.718
50_L133_Q0.087570.716
54_P143_L0.08750.715
8_P27_R0.087490.715
79_L119_I0.087150.713
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4huqS0.834513.10.942
4dveA0.65529.40.946
4humA0.65528.60.947
4hfiA0.75866.20.95
3mktA0.64835.70.951
3rlbA0.65525.10.952
3w4tA0.61384.40.953
3qnqA0.91033.70.954
3sxuB0.317230.957
3aqpA12.90.957
If you are interested in a protein containing this domain,
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