GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF202 - Domain of unknown function (DUF202)
Pfam: PF02656 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 73
Sequences: 1036
Seq/Len: 14.19
HH_delta: 0.852 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
12_A16_T0.386862.006
21_V56_G0.345581.792
24_G56_G0.338041.753
58_L62_Y0.304091.577
66_R69_R0.302621.569
14_I52_L0.289681.502
12_A15_R0.283261.469
1_R5_A0.281651.461
28_L34_D0.264421.371
6_N10_F0.260511.351
29_R71_R0.253971.317
5_A10_F0.248941.291
25_L34_D0.241371.252
61_I65_Y0.239561.242
7_E11_L0.239131.240
1_R4_L0.238831.239
17_A68_R0.238211.235
43_R47_V0.229291.189
53_I56_G0.226911.177
13_W22_G0.222981.156
43_R54_V0.221371.148
44_V51_L0.218321.132
15_R18_L0.217231.127
25_L53_I0.215421.117
43_R51_L0.215281.116
25_L29_R0.215071.115
50_L54_V0.213441.107
24_G53_I0.207331.075
67_Y71_R0.206241.070
3_G67_Y0.205321.065
43_R65_Y0.200621.040
6_N70_R0.193411.003
7_E30_F0.191560.993
23_V26_A0.190750.989
7_E25_L0.189960.985
46_K57_L0.189860.985
15_R66_R0.189580.983
4_L22_G0.189420.982
25_L32_S0.189260.981
57_L62_Y0.188940.980
29_R32_S0.187850.974
62_Y70_R0.186830.969
2_D67_Y0.18590.964
60_L64_I0.184290.956
7_E13_W0.184040.954
6_N71_R0.181040.939
9_T13_W0.180440.936
28_L49_G0.18010.934
65_Y69_R0.177230.919
12_A19_A0.176840.917
54_V61_I0.175810.912
20_L24_G0.173260.899
27_L48_L0.172930.897
17_A60_L0.172790.896
62_Y69_R0.171470.889
64_I68_R0.17130.888
17_A59_T0.171140.888
44_V65_Y0.167140.867
28_L52_L0.16640.863
49_G53_I0.16630.862
23_V45_S0.165470.858
22_G56_G0.162250.841
10_F14_I0.162240.841
31_F45_S0.161780.839
61_I69_R0.161550.838
30_F33_L0.158170.820
17_A24_G0.156850.813
31_F47_V0.156680.813
59_T64_I0.156490.812
11_L24_G0.155650.807
2_D29_R0.155570.807
3_G23_V0.154480.801
9_T12_A0.152530.791
34_D45_S0.152380.790
33_L67_Y0.152130.789
59_T69_R0.151950.788
45_S48_L0.151710.787
51_L54_V0.151550.786
43_R46_K0.150740.782
28_L32_S0.150480.780
26_A32_S0.148770.772
68_R71_R0.147970.767
3_G6_N0.147690.766
63_G68_R0.147680.766
27_L31_F0.146780.761
6_N13_W0.146510.760
44_V47_V0.145660.755
3_G10_F0.144560.750
5_A9_T0.144430.749
23_V49_G0.144320.748
47_V61_I0.144120.747
5_A8_R0.143980.747
21_V60_L0.143330.743
30_F62_Y0.142620.740
20_L63_G0.142230.738
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4av3A0.506818.30.852
4i0uA0.890414.80.857
4ev6A0.890411.50.864
2iubA0.890411.20.865
2yevB0.87678.80.87
3tdsE0.97268.20.872
1rz2A0.52056.10.879
1zzaA0.58960.879
1iijA0.47955.90.88
2ks1B0.54795.30.882
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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