GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
BacA - Bacitracin resistance protein BacA
Pfam: PF02673 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0292
Length: 259
Sequences: 1841
Seq/Len: 7.11
HH_delta: 0.965 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
59_D184_R0.549143.400
8_V26_V0.489233.029
153_A171_A0.467272.893
88_A185_F0.450042.786
119_I256_G0.439982.724
93_G196_G0.431042.669
9_Q48_T0.408272.528
60_I191_I0.392312.429
3_I224_V0.387252.398
172_G177_L0.384042.378
89_T193_A0.373932.315
123_L127_L0.364662.258
92_T193_A0.343272.125
104_E201_E0.343252.125
178_D181_E0.339972.105
199_L203_K0.329792.042
238_R242_R0.322851.999
2_A6_G0.319031.975
116_I120_I0.316821.962
130_R246_R0.310631.923
122_G253_I0.309241.915
196_G200_L0.300881.863
57_R61_W0.292751.813
148_L152_L0.291621.806
238_R241_K0.291171.803
21_G114_V0.286491.774
23_L41_D0.281911.745
250_I254_I0.280821.739
52_V233_I0.277491.718
224_V228_V0.276291.711
48_T229_G0.271231.679
7_I228_V0.268211.661
115_A256_G0.26551.644
99_F102_F0.264261.636
145_K149_I0.262661.626
6_G224_V0.261441.619
92_T155_G0.260231.611
86_I90_I0.259621.607
110_S113_V0.252261.562
95_V155_G0.250571.551
5_L23_L0.24921.543
239_F243_R0.247111.530
89_T93_G0.24531.519
100_K201_E0.243421.507
5_L26_V0.237251.469
80_R84_L0.23721.469
100_K104_E0.23431.451
227_V231_L0.231671.434
200_L203_K0.231291.432
195_L199_L0.23071.428
126_W246_R0.230271.426
180_E241_K0.229491.421
236_L243_R0.226761.404
88_A189_L0.226591.403
55_Y234_K0.225331.395
200_L204_D0.222381.377
149_I175_L0.22031.364
103_I158_L0.215851.336
39_A43_F0.215711.336
239_F247_P0.214541.328
4_I8_V0.213041.319
45_H194_I0.212221.314
3_I7_I0.211431.309
25_L259_V0.210421.303
102_F106_L0.21031.302
22_H251_Y0.209041.294
152_L156_L0.208591.292
2_A220_I0.208311.290
54_I226_F0.206651.280
87_I144_F0.20661.279
183_A240_L0.205771.274
183_A237_L0.204361.265
125_L129_D0.202971.257
14_F229_G0.201211.246
62_R78_D0.200391.241
143_T146_D0.19931.234
93_G97_L0.198991.232
226_F230_Y0.198451.229
124_L170_T0.193641.199
117_A120_I0.193251.197
56_F237_L0.192391.191
17_I236_L0.191531.186
102_F105_A0.191471.186
223_V227_V0.190761.181
49_L190_S0.189551.174
138_D141_D0.187661.162
220_I224_V0.187211.159
166_G173_L0.182391.129
201_E204_D0.18081.119
196_G199_L0.179961.114
50_L226_F0.179421.111
113_V117_A0.17911.109
45_H48_T0.17891.108
92_T158_L0.178351.104
2_A40_F0.176181.091
61_W65_K0.175021.084
129_D244_K0.174741.082
228_V232_A0.173951.077
117_A159_I0.173411.074
121_T252_R0.172771.070
246_R250_I0.172641.069
95_V158_L0.170391.055
146_D175_L0.169571.050
144_F148_L0.169261.048
46_L194_I0.167371.036
81_L188_L0.167061.034
162_I167_A0.166971.034
12_T17_I0.165281.023
11_L17_I0.164641.019
219_L223_V0.164261.017
95_V99_F0.16341.012
20_S45_H0.162691.007
3_I220_I0.162371.005
158_L193_A0.161380.999
20_S49_L0.161110.998
183_A236_L0.159960.990
87_I148_L0.15860.982
180_E184_R0.157590.976
129_D179_R0.156970.972
138_D181_E0.156940.972
93_G98_L0.156520.969
58_K62_R0.156370.968
27_S32_W0.156150.967
126_W249_A0.155360.962
44_L221_G0.155160.961
1_Q30_L0.154840.959
93_G96_G0.154710.958
80_R83_L0.154670.958
216_P219_L0.153440.950
2_A217_P0.153430.950
38_L45_H0.152920.947
155_G158_L0.152650.945
139_E181_E0.152470.944
119_I253_I0.152390.944
146_D172_G0.152070.942
37_G41_D0.151710.939
2_A224_V0.151650.939
128_A170_T0.151280.937
146_D177_L0.150960.935
216_P220_I0.150830.934
99_F103_I0.150590.932
56_F184_R0.150450.932
95_V152_L0.150240.930
231_L234_K0.150140.930
159_I162_I0.150.929
60_I64_L0.149560.926
79_R83_L0.148980.922
225_A230_Y0.14860.920
94_V97_L0.147880.916
20_S48_T0.147420.913
137_K146_D0.14720.911
124_L128_A0.146580.908
90_I93_G0.14630.906
121_T162_I0.145620.902
58_K65_K0.145610.902
199_L204_D0.145420.900
42_V201_E0.145010.898
81_L139_E0.14490.897
232_A235_W0.14450.895
162_I252_R0.144080.892
88_A193_A0.143980.891
58_K64_L0.143660.889
230_Y234_K0.14280.884
172_G175_L0.142360.881
4_I26_V0.141970.879
137_K141_D0.14180.878
113_V159_I0.141540.876
26_V30_L0.141260.875
9_Q20_S0.141170.874
20_S23_L0.140970.873
213_G216_P0.140530.870
150_I177_L0.140410.869
120_I124_L0.140320.869
214_S218_L0.139760.865
63_L82_L0.139620.864
24_V114_V0.139390.863
92_T96_G0.139170.862
127_L131_L0.138980.861
125_L166_G0.138440.857
46_L198_G0.138310.856
254_I257_I0.137870.854
45_H49_L0.13740.851
219_L222_F0.137380.851
248_F251_Y0.137220.850
39_A205_L0.136640.846
253_I257_I0.136620.846
25_L255_L0.136540.845
239_F244_K0.136050.842
190_S194_I0.1360.842
126_W250_I0.135880.841
153_A156_L0.134710.834
42_V197_A0.134660.834
170_T249_A0.1340.830
25_L118_L0.133930.829
53_L60_I0.132760.822
112_L116_I0.132650.821
82_L85_I0.132610.821
77_P80_R0.13250.820
255_L258_I0.132380.820
215_W219_L0.131860.816
237_L240_L0.131850.816
23_L240_L0.131420.814
118_L252_R0.129990.805
9_Q229_G0.129980.805
23_L225_A0.12990.804
44_L49_L0.129480.802
55_Y230_Y0.129320.801
201_E205_L0.128960.798
12_T22_H0.128530.796
54_I57_R0.128190.794
115_A119_I0.127940.792
230_Y247_P0.127210.788
159_I170_T0.127190.788
27_S30_L0.127140.787
142_I181_E0.127070.787
14_F23_L0.127040.787
94_V98_L0.127040.787
84_L144_F0.127020.786
179_R244_K0.126950.786
28_H111_P0.126160.781
216_P223_V0.125970.780
203_K219_L0.125940.780
146_D149_I0.125090.775
48_T60_I0.125070.774
253_I256_G0.124750.772
20_S44_L0.124540.771
115_A259_V0.124390.770
190_S226_F0.124370.770
24_V111_P0.12430.770
58_K61_W0.123890.767
101_D105_A0.123730.766
13_E19_S0.123480.765
207_S212_S0.123480.765
15_L179_R0.123350.764
7_I11_L0.12310.762
234_K238_R0.123010.762
84_L147_A0.122580.759
128_A174_L0.122380.758
55_Y237_L0.122190.757
9_Q121_T0.122160.756
122_G126_W0.121120.750
66_G83_L0.120880.748
170_T173_L0.120670.747
149_I171_A0.120450.746
94_V227_V0.120120.744
48_T166_G0.120070.743
142_I177_L0.120050.743
244_K252_R0.120030.743
33_D149_I0.119830.742
106_L113_V0.119660.741
38_L41_D0.118650.735
91_P183_A0.118640.735
113_V229_G0.118590.734
9_Q44_L0.118060.731
111_P259_V0.117840.730
49_L52_V0.117290.726
98_L101_D0.117140.725
110_S259_V0.116740.723
50_L223_V0.116630.722
97_L196_G0.116540.722
45_H252_R0.116210.720
247_P250_I0.115750.717
166_G170_T0.115580.716
129_D245_L0.115510.715
54_I255_L0.115180.713
126_W130_R0.115160.713
21_G97_L0.115160.713
25_L111_P0.115120.713
83_L87_I0.115080.713
110_S114_V0.114950.712
27_S41_D0.114380.708
79_R202_L0.114240.707
123_L126_W0.114170.707
100_K105_A0.114060.706
61_W64_L0.11340.702
114_V118_L0.113340.702
100_K204_D0.112690.698
167_A190_S0.112690.698
101_D201_E0.112430.696
189_L193_A0.111680.691
125_L170_T0.111450.690
202_L205_L0.11140.690
33_D172_G0.109870.680
126_W129_D0.109750.680
119_I257_I0.109670.679
152_L155_G0.109560.678
149_I152_L0.109550.678
121_T167_A0.109330.677
168_T186_S0.109160.676
83_L86_I0.1090.675
56_F170_T0.108910.674
95_V98_L0.108730.673
24_V226_F0.108270.670
150_I189_L0.108150.670
6_G17_I0.107970.669
5_L231_L0.107640.666
90_I94_V0.107510.666
150_I172_G0.107430.665
44_L194_I0.107320.664
9_Q49_L0.107240.664
98_L103_I0.107180.664
220_I223_V0.106850.662
21_G245_L0.106520.660
9_Q45_H0.106390.659
121_T156_L0.106220.658
21_G121_T0.106030.657
43_F124_L0.105960.656
114_V117_A0.105850.655
86_I89_T0.105790.655
228_V233_I0.105460.653
136_R205_L0.105160.651
249_A252_R0.105140.651
166_G196_G0.105130.651
162_I229_G0.104910.650
228_V231_L0.104720.648
9_Q89_T0.104080.644
243_R247_P0.1040.644
3_I136_R0.103890.643
98_L102_F0.103510.641
118_L194_I0.103440.640
10_G13_E0.103440.640
168_T173_L0.10340.640
84_L88_A0.103380.640
241_K244_K0.103360.640
46_L169_I0.103270.639
150_I185_F0.102860.637
86_I200_L0.102640.636
49_L245_L0.102550.635
41_D172_G0.102420.634
87_I102_F0.102160.633
215_W223_V0.101890.631
198_G202_L0.101850.631
57_R64_L0.101830.630
170_T189_L0.101810.630
207_S211_D0.101650.629
21_G37_G0.101620.629
52_V240_L0.101520.629
20_S194_I0.10150.628
35_E38_L0.101390.628
122_G125_L0.101140.626
169_I245_L0.101120.626
208_A211_D0.100730.624
107_F171_A0.10070.623
66_G78_D0.100330.621
82_L86_I0.100080.620
92_T100_K0.099890.618
103_I159_I0.099880.618
14_F22_H0.099860.618
179_R251_Y0.099710.617
130_R133_R0.099640.617
53_L191_I0.099470.616
63_L259_V0.099410.616
118_L255_L0.099240.614
93_G155_G0.099140.614
28_H32_W0.099010.613
25_L100_K0.098990.613
25_L81_L0.098910.612
99_F215_W0.098790.612
24_V41_D0.098550.610
25_L167_A0.098450.610
92_T111_P0.098340.609
4_I30_L0.098230.608
98_L105_A0.098160.608
193_A200_L0.098150.608
64_L219_L0.0980.607
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3mp7B0.2355200.965
3ne5A0.806912.40.968
1fdmA0.19319.80.97
1iflA0.20468.40.971
1ifkA0.19698.10.971
2wwbB0.26257.40.971
1q90G0.13515.20.973
3l1lA0.45955.10.973
2ww9B0.30550.973
4dx5A0.79924.80.974
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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