GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Colicin_V - Colicin V production protein
Pfam: PF02674 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0292
Length: 146
Sequences: 1426
Seq/Len: 9.77
HH_delta: 0.898 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
12_F108_K0.429053.166
13_A102_A0.410753.031
85_R97_D0.336712.485
9_L106_L0.318162.348
45_L69_L0.290072.140
5_I137_F0.261331.928
34_A73_V0.260591.923
37_V73_V0.257731.902
12_F109_G0.249861.844
21_F100_L0.244271.802
19_R24_E0.240041.771
37_V69_L0.233371.722
30_G77_V0.224871.659
1_I5_I0.218111.609
24_E104_L0.216811.600
13_A106_L0.213041.572
36_F40_L0.203071.498
12_F105_G0.195851.445
9_L109_G0.192691.422
90_K93_L0.190841.408
24_E108_K0.187371.383
9_L13_A0.18271.348
3_I7_I0.17811.314
49_L68_I0.177771.312
15_K19_R0.177251.308
42_Y62_N0.176931.306
31_L104_L0.173611.281
46_A62_N0.171051.262
23_R85_R0.168941.247
8_I109_G0.168251.241
14_I18_R0.166631.230
99_L103_L0.163561.207
135_S138_Y0.162621.200
17_Y102_A0.161681.193
24_E27_S0.161481.192
92_F95_W0.160351.183
45_L65_A0.159481.177
2_D97_D0.158151.167
16_G21_F0.157941.165
16_G81_G0.156611.156
44_P47_P0.154661.141
9_L113_L0.152621.126
35_L38_A0.15231.124
70_F74_Y0.151321.117
6_L45_L0.151231.116
69_L73_V0.150311.109
34_A70_F0.147911.091
38_A117_L0.147171.086
42_Y65_A0.146311.080
15_K18_R0.143931.062
79_I83_L0.143331.058
38_A66_F0.14311.056
104_L108_K0.143091.056
129_Q138_Y0.141891.047
111_L114_S0.140341.036
60_F63_I0.138821.024
8_I116_L0.138261.020
6_L10_L0.138131.019
137_F140_F0.137721.016
22_I91_P0.137491.015
97_D101_G0.137371.014
117_L132_I0.136981.011
67_I70_F0.136521.007
34_A74_Y0.135771.002
4_I7_I0.135350.999
38_A65_A0.135040.996
116_L134_N0.134760.994
49_L65_A0.134310.991
81_G85_R0.133840.988
84_L88_V0.133740.987
120_L126_P0.133380.984
16_G102_A0.131220.968
76_I80_I0.130610.964
10_L14_I0.130240.961
11_I35_L0.129930.959
40_L44_P0.129920.959
8_I113_L0.12970.957
73_V98_R0.129680.957
32_I40_L0.129650.957
124_P127_G0.129620.956
12_F31_L0.129590.956
14_I17_Y0.129280.954
88_V91_P0.129220.953
110_L141_L0.129210.953
91_P94_G0.129050.952
41_F72_L0.128770.950
46_A65_A0.127790.943
50_S76_I0.127420.940
109_G141_L0.127330.940
51_N113_L0.127330.940
91_P97_D0.127130.938
95_W98_R0.126970.937
88_V97_D0.126920.937
114_S118_F0.126190.931
10_L144_I0.125840.929
32_I36_F0.125530.926
26_F84_L0.125170.924
9_L102_A0.124930.922
23_R80_I0.124760.921
36_F106_L0.124640.920
110_L114_S0.124360.918
88_V95_W0.123810.914
45_L48_F0.123240.909
132_I138_Y0.122530.904
31_L34_A0.122190.902
8_I12_F0.121860.899
21_F81_G0.12140.896
42_Y138_Y0.121060.893
34_A81_G0.12090.892
32_I104_L0.119330.881
26_F81_G0.118880.877
11_I136_R0.118420.874
70_F77_V0.117560.867
117_L142_I0.117540.867
1_I131_W0.117390.866
38_A42_Y0.117170.865
130_E134_N0.116940.863
114_S138_Y0.116780.862
75_I103_L0.115940.855
18_R23_R0.115890.855
101_G105_G0.115670.854
89_K113_L0.115660.853
34_A38_A0.115540.853
71_V79_I0.1150.849
129_Q144_I0.114920.848
72_L76_I0.114610.846
7_I11_I0.114530.845
24_E105_G0.114410.844
33_V77_V0.114040.841
41_F69_L0.113930.841
97_D131_W0.112890.833
31_L109_G0.112670.831
2_D136_R0.112580.831
30_G106_L0.112440.830
5_I113_L0.112040.827
105_G108_K0.112030.827
65_A69_L0.111670.824
26_F108_K0.111540.823
32_I144_I0.111330.821
91_P114_S0.110920.818
114_S141_L0.110820.818
22_I90_K0.110660.817
60_F78_R0.110520.816
22_I88_V0.110240.813
138_Y141_L0.109810.810
40_L80_I0.109790.810
36_F39_F0.109630.809
58_P72_L0.109620.809
87_I93_L0.109510.808
49_L57_S0.108920.804
113_L141_L0.108640.802
13_A18_R0.108630.802
74_Y78_R0.108280.799
76_I79_I0.108250.799
22_I138_Y0.107920.796
93_L97_D0.107740.795
26_F88_V0.10770.795
50_S126_P0.106170.783
70_F73_V0.106030.782
57_S61_A0.105930.782
68_I137_F0.105760.780
2_D34_A0.10540.778
125_N143_N0.104460.771
17_Y110_L0.104340.770
29_I130_E0.104190.769
86_R99_L0.103850.766
2_D101_G0.103790.766
70_F105_G0.103690.765
48_F65_A0.103260.762
10_L126_P0.103190.761
3_I33_V0.103180.761
126_P129_Q0.103070.761
24_E48_F0.102740.758
93_L104_L0.102310.755
81_G114_S0.102260.755
89_K93_L0.102130.754
5_I74_Y0.102060.753
32_I143_N0.101880.752
121_N142_I0.101880.752
88_V92_F0.101680.750
63_I67_I0.101250.747
29_I66_F0.101220.747
8_I59_P0.101130.746
66_F70_F0.101070.746
25_L116_L0.10090.745
21_F101_G0.10090.745
28_L76_I0.100860.744
3_I6_L0.100840.744
19_R78_R0.100750.743
9_L141_L0.10050.742
86_R107_A0.100420.741
3_I103_L0.100370.741
8_I102_A0.100320.740
35_L111_L0.10020.739
99_L102_A0.100150.739
72_L80_I0.10.738
37_V76_I0.099870.737
8_I112_I0.099170.732
122_L129_Q0.09850.727
29_I132_I0.098480.727
26_F89_K0.098460.727
31_L108_K0.097760.721
88_V93_L0.097650.721
35_L39_F0.097360.718
43_P143_N0.097190.717
91_P139_P0.09710.716
38_A98_R0.096560.712
109_G113_L0.096520.712
31_L74_Y0.096520.712
22_I97_D0.09650.712
1_I138_Y0.096380.711
66_F119_L0.096170.710
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4aw6A0.842521.20.898
4il3A0.86313.60.906
4k1cA0.41140.925
1u5lA0.31513.10.929
3hzqA0.53422.70.931
2nwlA0.85622.60.932
4hfiA0.78082.60.932
2kncB0.36992.50.932
3rlbA0.80142.40.933
2vv5A0.73292.20.934
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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