GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Sterile - Male sterility protein
Pfam: PF03015 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 94
Sequences: 586
Seq/Len: 6.23
HH_delta: 0.897 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
8_Y24_V0.287652.458
61_P64_R0.233091.992
7_A11_D0.230041.966
11_D21_P0.215741.844
51_N69_F0.214731.835
68_N73_S0.206341.763
39_Y43_N0.202671.732
3_H7_A0.195831.674
4_F31_R0.185721.587
33_A37_L0.178811.528
39_Y49_N0.176981.513
76_W83_Y0.174211.489
49_N53_R0.168251.438
51_N55_L0.166761.425
27_Y30_I0.156151.334
56_W69_F0.155511.329
33_A36_V0.15521.326
88_R94_E0.153961.316
76_W87_I0.15071.288
15_R21_P0.150191.284
3_H6_P0.147711.262
51_N75_D0.143971.230
60_S74_I0.1411.205
22_R27_Y0.140841.204
3_H11_D0.139781.195
70_D76_W0.137141.172
45_W59_L0.137121.172
44_E49_N0.133241.139
59_L64_R0.131521.124
69_F76_W0.130511.115
27_Y31_R0.129581.107
3_H27_Y0.125231.070
40_F43_N0.123221.053
31_R34_L0.122471.047
62_E65_E0.120231.028
67_F86_G0.118681.014
80_F84_I0.118171.010
56_W71_I0.117981.008
6_P23_M0.117791.007
11_D20_K0.117081.001
48_D80_F0.11680.998
4_F24_V0.116690.997
56_W64_R0.116390.995
23_M90_Y0.116330.994
20_K24_V0.116290.994
16_L65_E0.11540.986
3_H71_I0.115140.984
41_T52_T0.114020.974
43_N91_L0.113440.969
83_Y87_I0.112880.965
33_A87_I0.112780.964
25_K44_E0.111530.953
50_D58_R0.111410.952
30_I37_L0.111140.950
40_F86_G0.11110.949
9_L12_L0.110840.947
4_F8_Y0.110830.947
8_Y15_R0.110790.947
10_L14_L0.110740.946
19_Q23_M0.110670.946
4_F30_I0.110170.942
37_L45_W0.109940.940
68_N89_K0.109250.934
25_K57_E0.109130.933
28_R36_V0.109110.932
37_L63_D0.106950.914
76_W86_G0.10690.914
11_D18_G0.106080.907
12_L16_L0.105660.903
47_F55_L0.105240.899
70_D79_Y0.104730.895
18_G21_P0.104660.894
52_T72_R0.104340.892
35_E80_F0.10350.885
2_F75_D0.102830.879
58_R67_F0.102350.875
57_E74_I0.102260.874
19_Q39_Y0.102150.873
11_D14_L0.102120.873
39_Y83_Y0.101990.872
87_I92_L0.101670.869
32_K76_W0.100630.860
86_G90_Y0.100570.859
5_L8_Y0.100480.859
72_R81_R0.100350.858
70_D73_S0.100260.857
14_L44_E0.100030.855
65_E77_E0.0990.846
29_K42_T0.098880.845
40_F45_W0.098690.843
44_E47_F0.098640.843
8_Y11_D0.098580.842
65_E72_R0.098570.842
17_F66_I0.098510.842
71_I74_I0.098380.841
7_A92_L0.097430.833
34_L38_E0.096960.829
30_I51_N0.096720.827
66_I75_D0.096680.826
50_D53_R0.096630.826
81_R85_P0.096570.825
23_M26_I0.096510.825
50_D54_R0.096290.823
85_P89_K0.095970.820
87_I91_L0.095950.820
54_R66_I0.095850.819
61_P65_E0.095560.817
22_R31_R0.095240.814
50_D57_E0.09520.814
46_I75_D0.095120.813
19_Q69_F0.094880.811
39_Y48_D0.094870.811
2_F89_K0.094270.806
53_R75_D0.094190.805
45_W83_Y0.094160.805
79_Y85_P0.094010.803
59_L63_D0.093680.801
5_L19_Q0.092860.794
6_P90_Y0.092290.789
11_D88_R0.092190.788
79_Y86_G0.091680.784
14_L20_K0.090820.776
57_E72_R0.090810.776
40_F82_N0.090170.771
27_Y47_F0.090040.770
57_E64_R0.089970.769
54_R57_E0.089820.768
40_F63_D0.089570.765
90_Y93_K0.089530.765
11_D22_R0.089290.763
29_K33_A0.089170.762
14_L94_E0.089130.762
76_W79_Y0.088690.758
54_R70_D0.08810.753
29_K51_N0.088090.753
29_K34_L0.08780.750
22_R33_A0.087750.750
49_N85_P0.087180.745
64_R67_F0.087120.745
36_V43_N0.087040.744
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2eo2A0.6277270.897
3zxuA0.851118.20.905
1ni3A0.989417.40.906
3st7A0.9681120.912
4adnA0.957410.20.915
4a4aA0.968110.20.915
4g63A0.89369.10.916
2yb5A0.957490.917
2ohfA0.98948.90.917
2x2hA0.93626.30.922
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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