GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
TspO_MBR - TspOMBR family
Pfam: PF03073 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 148
Sequences: 1157
Seq/Len: 7.82
HH_delta: 0.926 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
89_I102_I0.652333.622
107_L136_S0.61283.403
58_L121_S0.560263.111
110_L135_L0.554543.079
97_G146_W0.515782.864
34_W140_Y0.504222.800
39_W43_P0.429382.384
100_L142_N0.372632.069
100_L143_F0.368092.044
82_L109_L0.356581.980
106_L131_Y0.322361.790
113_L128_L0.312451.735
114_I125_G0.302351.679
25_W94_R0.300611.669
107_L135_L0.297531.652
75_L116_A0.295481.641
25_W96_L0.287841.598
8_L50_I0.283641.575
118_W125_G0.275621.530
75_L112_A0.272881.515
86_W142_N0.261181.450
83_N131_Y0.260531.447
82_L102_I0.256741.426
56_S76_Y0.254381.412
41_F86_W0.25181.398
113_L117_F0.238321.323
49_Y83_N0.236751.315
14_S18_T0.236381.313
31_K35_T0.232251.290
49_Y131_Y0.230611.280
104_L108_G0.228241.267
7_P56_S0.227591.264
52_M56_S0.222541.236
59_V117_F0.218321.212
112_A116_A0.217861.210
10_V84_F0.216591.203
83_N106_L0.215871.199
26_Y91_F0.211311.173
107_L139_T0.210911.171
58_L61_R0.209771.165
10_V14_S0.206451.146
40_V137_F0.205971.144
81_A85_A0.205471.141
103_I135_L0.203491.130
111_A132_L0.203111.128
31_K145_I0.201291.118
8_L11_G0.199571.108
78_I109_L0.19761.097
54_I57_Y0.196051.089
99_A102_I0.195191.084
63_G69_R0.194711.081
7_P76_Y0.193891.077
12_F16_Y0.193731.076
79_Q109_L0.193481.074
33_S140_Y0.19161.064
56_S73_L0.191411.063
140_Y144_S0.190651.059
14_S17_L0.190551.058
33_S144_S0.188771.048
11_G53_G0.186961.038
26_Y29_L0.185211.028
103_I142_N0.184971.027
103_I139_T0.184621.025
55_A59_V0.182491.013
25_W38_G0.182291.012
53_G57_Y0.182151.011
25_W31_K0.180671.003
48_L137_F0.180651.003
107_L111_A0.178350.990
100_L146_W0.176440.980
35_T96_L0.1760.977
122_R126_L0.175910.977
126_L129_I0.175630.975
45_W138_A0.175180.973
93_L96_L0.175090.972
43_P46_T0.173850.965
48_L130_P0.17350.963
76_Y117_F0.173160.961
41_F138_A0.171150.950
107_L110_L0.17010.945
55_A128_L0.169390.941
89_I99_A0.168560.936
86_W138_A0.168110.933
114_I129_I0.167030.927
25_W29_L0.16470.915
137_F141_L0.164550.914
116_A119_K0.164160.912
7_P53_G0.163290.907
49_Y80_L0.163240.906
43_P47_I0.163070.905
82_L105_A0.162880.904
42_G138_A0.162250.901
89_I98_L0.159930.888
95_S99_A0.159110.883
35_T137_F0.158860.882
112_A115_F0.158280.879
123_T126_L0.156930.871
79_Q113_L0.156820.871
78_I108_G0.156680.870
139_T142_N0.156550.869
86_W90_F0.156350.868
129_I133_A0.155640.864
95_S98_L0.154110.856
134_W138_A0.153230.851
106_L135_L0.151570.842
34_W144_S0.151260.840
118_W126_L0.148920.827
13_L17_L0.148560.825
133_A137_F0.14840.824
139_T143_F0.148060.822
29_L32_P0.145750.809
79_Q83_N0.144520.802
62_K121_S0.144240.801
132_L136_S0.14410.800
57_Y60_W0.14380.798
85_A88_P0.142890.793
56_S60_W0.142250.790
40_V44_V0.141160.784
55_A124_A0.141130.784
88_P93_L0.139030.772
107_L132_L0.137910.766
45_W48_L0.137670.764
141_L145_I0.137460.763
79_Q110_L0.136680.759
34_W141_L0.136490.758
73_L77_A0.136440.758
49_Y52_M0.136080.756
25_W35_T0.13580.754
11_G34_W0.135680.753
11_G14_S0.135530.753
86_W103_I0.135180.751
52_M79_Q0.13510.750
46_T50_I0.135060.750
8_L14_S0.134960.749
106_L110_L0.134780.748
123_T127_L0.134470.747
19_P23_S0.1340.744
60_W78_I0.133870.743
87_S91_F0.133230.740
79_Q82_L0.133030.739
91_F141_L0.132120.734
41_F45_W0.131620.731
42_G87_S0.131480.730
76_Y128_L0.13140.730
40_V43_P0.13130.729
97_G101_I0.130430.724
111_A115_F0.129590.720
118_W122_R0.129570.719
24_E28_S0.129530.719
9_V12_F0.12950.719
88_P103_I0.129280.718
14_S87_S0.128520.714
42_G46_T0.127230.706
63_G70_R0.126510.702
10_V13_L0.126240.701
75_L109_L0.1260.700
114_I128_L0.125690.698
48_L52_M0.125570.697
55_A113_L0.125410.696
53_G56_S0.124880.693
48_L138_A0.124530.691
8_L12_F0.12410.689
36_P41_F0.123830.688
114_I132_L0.123460.686
47_I118_W0.123140.684
68_R81_A0.122550.680
102_I109_L0.121980.677
71_R78_I0.121810.676
35_T43_P0.121510.675
39_W44_V0.120470.669
110_L113_L0.120420.669
59_V73_L0.120020.666
55_A117_F0.119940.666
7_P52_M0.119860.666
59_V120_I0.119350.663
72_A117_F0.119330.663
90_F145_I0.119150.662
25_W85_A0.118970.661
48_L87_S0.118830.660
44_V48_L0.118790.660
37_P138_A0.118680.659
75_L125_G0.118590.658
39_W42_G0.118160.656
143_F146_W0.118130.656
36_P138_A0.11780.654
60_W63_G0.11740.652
38_G138_A0.117150.650
34_W137_F0.117130.650
41_F142_N0.117040.650
76_Y80_L0.116950.649
67_P81_A0.116330.646
60_W72_A0.11560.642
117_F124_A0.115370.641
15_G19_P0.115340.640
30_K33_S0.114960.638
72_A113_L0.114610.636
7_P19_P0.114570.636
63_G120_I0.114060.633
71_R74_A0.113840.632
30_K46_T0.11340.630
14_S88_P0.112970.627
57_Y76_Y0.112890.627
48_L80_L0.112790.626
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3dh4A0.47310.40.926
2a65A0.45275.40.934
2rlwA0.22974.50.937
4i0uA0.35813.50.94
4ev6A0.35812.60.944
2iubA0.35812.30.945
4he8H0.75681.50.949
3rfrC0.84461.30.952
4h44A0.89191.20.953
2losA0.66221.20.953
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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