GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
CcmB - CcmB protein
Pfam: PF03379 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0181
Length: 215
Sequences: 6648
Seq/Len: 30.92
HH_delta: 0.926 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
6_R10_R0.886554.558
5_F100_L0.699763.598
86_P89_A0.602053.095
5_F96_L0.584173.003
71_E94_K0.520952.678
4_L93_G0.513092.638
8_D94_K0.441362.269
64_L142_G0.40642.089
5_F93_G0.39462.029
13_F16_K0.384291.976
10_R13_F0.375441.930
93_G97_A0.361691.860
85_V90_I0.355921.830
125_P129_L0.355761.829
71_E76_T0.342841.763
138_L142_G0.333281.713
42_D45_A0.332971.712
150_A154_G0.330911.701
126_L129_L0.327461.684
134_G138_L0.307171.579
53_W134_G0.306521.576
103_F132_L0.29591.521
3_A6_R0.292331.503
65_N159_L0.290881.495
46_R50_G0.288571.484
57_L138_L0.286051.471
9_L13_F0.28331.457
150_A153_R0.277661.428
10_R14_R0.276761.423
123_S126_L0.269021.383
129_L133_L0.268341.380
22_M26_F0.268271.379
151_G154_G0.26281.351
49_P53_W0.261731.346
125_P128_L0.261291.343
99_W136_L0.255761.315
124_W128_L0.255741.315
160_P164_L0.250541.288
49_P52_L0.250031.285
15_S18_G0.246571.268
43_L46_R0.244261.256
60_S138_L0.242651.248
12_E101_L0.238711.227
30_I48_A0.235841.213
60_S95_L0.234361.205
107_L128_L0.234261.204
15_S43_L0.233411.200
34_S47_V0.227941.172
70_R74_D0.223771.150
19_L23_L0.221961.141
92_L96_L0.221571.139
95_L140_A0.219511.129
59_A98_N0.218271.122
132_L136_L0.216321.112
52_L106_E0.215661.109
51_L55_A0.212911.095
22_M29_V0.212771.094
88_S92_L0.210961.085
48_A113_F0.20791.069
66_R70_R0.205751.058
43_L47_V0.204851.053
7_K10_R0.204311.050
65_N68_F0.203741.047
72_Y77_L0.201411.036
45_A119_L0.201331.035
67_S151_G0.200031.028
128_L132_L0.199851.027
18_G21_S0.198821.022
21_S24_L0.19831.020
80_L83_S0.19811.018
55_A105_P0.198091.018
126_L130_S0.198091.018
156_E160_P0.19781.017
115_L120_P0.196431.010
149_A156_E0.195751.006
77_L90_I0.193320.994
70_R73_E0.19330.994
144_L147_A0.192290.989
106_E110_F0.192140.988
8_D11_L0.190690.980
71_E75_G0.190670.980
25_F29_V0.190150.978
89_A92_L0.189950.977
137_G140_A0.189630.975
79_Q82_L0.189420.974
8_D97_A0.188440.969
81_L87_R0.188170.967
76_T79_Q0.188060.967
135_T138_L0.187510.964
107_L111_P0.186940.961
56_L134_G0.186050.957
145_L155_R0.185410.953
76_T80_L0.183070.941
149_A155_R0.181950.935
4_L7_K0.180440.928
30_I52_L0.179070.921
100_L104_L0.177860.914
50_G111_P0.177080.910
64_L101_L0.17560.903
61_L145_L0.1750.900
67_S94_K0.174780.899
78_E81_L0.174250.896
87_R93_G0.17370.893
5_F9_L0.17350.892
111_P115_L0.17240.886
26_F30_I0.171890.884
64_L146_A0.170270.875
4_L85_V0.169650.872
7_K71_E0.169470.871
114_A120_P0.169420.871
34_S52_L0.169290.870
62_L163_L0.169030.869
157_I160_P0.1690.869
94_K97_A0.168720.867
143_T146_A0.167030.859
84_P87_R0.166630.857
32_I36_A0.165530.851
51_L64_L0.164910.848
153_R156_E0.164760.847
85_V130_S0.163570.841
47_V50_G0.1630.838
77_L87_R0.162580.836
122_S125_P0.162110.833
21_S26_F0.161210.829
141_I162_L0.16120.829
73_E152_A0.161060.828
108_I111_P0.160840.827
58_F62_L0.16070.826
147_A150_A0.16060.826
54_I163_L0.160380.825
96_L100_L0.159780.821
93_G96_L0.159680.821
56_L131_L0.158570.815
115_L119_L0.158350.814
50_G58_F0.158010.812
3_A7_K0.157680.811
59_A63_G0.156960.807
28_L31_V0.156350.804
135_T139_A0.15620.803
12_E15_S0.156160.803
91_F143_T0.155790.801
23_L26_F0.155620.800
162_L165_P0.155620.800
102_L135_T0.154670.795
146_A155_R0.153760.791
151_G161_L0.153530.789
56_L139_A0.153510.789
102_L106_E0.152490.784
52_L113_F0.152160.782
140_A147_A0.152020.782
21_S154_G0.151790.780
72_Y150_A0.151720.780
80_L85_V0.151630.780
103_F106_E0.15160.779
160_P166_L0.15140.778
85_V93_G0.151040.777
61_L159_L0.151020.776
9_L97_A0.150720.775
49_P54_I0.150540.774
6_R107_L0.150320.773
83_S147_A0.150270.773
110_F121_I0.149980.771
75_G84_P0.149120.767
10_R23_L0.148550.764
48_A114_A0.148360.763
73_E148_L0.14810.761
65_N155_R0.14810.761
77_L153_R0.147980.761
31_V35_F0.147960.761
19_L24_L0.147850.760
17_E20_L0.147810.760
53_W138_L0.147380.758
16_K19_L0.147130.756
66_R156_E0.14710.756
41_P79_Q0.146780.755
17_E21_S0.146690.754
48_A137_G0.146660.754
94_K98_N0.146630.754
90_I93_G0.145990.751
9_L100_L0.145980.751
73_E95_L0.145670.749
146_A150_A0.144720.744
152_A166_L0.143670.739
50_G53_W0.143140.736
100_L120_P0.14270.734
35_F38_G0.142410.732
95_L98_N0.142410.732
51_L168_I0.142150.731
76_T81_L0.141920.730
29_V33_F0.141720.729
149_A154_G0.141560.728
76_T90_I0.141040.725
103_F107_L0.141010.725
33_F54_I0.140830.724
56_L102_L0.140230.721
146_A154_G0.140180.721
79_Q83_S0.139770.719
108_I112_L0.139440.717
77_L147_A0.138860.714
8_D77_L0.138440.712
69_A73_E0.138310.711
154_G157_I0.138270.711
27_L34_S0.138250.711
98_N165_P0.137630.708
89_A93_G0.137260.706
21_S25_F0.137080.705
80_L84_P0.137020.704
58_F166_L0.136950.704
123_S127_L0.136940.704
133_L145_L0.136750.703
158_L161_L0.136640.703
143_T147_A0.136120.700
72_Y92_L0.135970.699
163_L167_L0.135970.699
97_A139_A0.135970.699
33_F37_L0.13590.699
105_P108_I0.135740.698
6_R9_L0.135350.696
148_L159_L0.1350.694
28_L32_I0.134980.694
148_L158_L0.134940.694
15_S80_L0.134820.693
57_L134_G0.13450.691
9_L161_L0.13450.691
78_E82_L0.134260.690
92_L111_P0.134110.689
149_A158_L0.1340.689
48_A52_L0.133740.688
98_N164_L0.133580.687
24_L27_L0.133370.686
49_P135_T0.133290.685
57_L91_F0.133240.685
69_A151_G0.132920.683
95_L139_A0.13290.683
29_V54_I0.132890.683
60_S134_G0.132840.683
62_L65_N0.13260.682
93_G166_L0.132260.680
25_F28_L0.132140.679
3_A8_D0.132060.679
65_N146_A0.131990.679
89_A130_S0.131840.678
24_L95_L0.131770.677
120_P123_S0.131640.677
14_R109_I0.131210.675
12_E105_P0.131180.674
59_A62_L0.130890.673
87_R90_I0.130720.672
58_F160_P0.130310.670
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3zuxA0.87448.90.926
4humA0.934990.926
2iubA0.33955.20.933
2l9uA0.15814.50.935
4he8J0.40473.40.938
4ev6A0.33493.40.938
3j1zP0.92563.50.938
4kjsA0.52562.90.94
4hygA0.33022.90.94
4k1cA0.669830.94
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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