GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
UPF0126 - UPF0126 domain
Pfam: PF03458 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 80
Sequences: 2155
Seq/Len: 26.94
HH_delta: 0.877 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
10_G69_G0.701292.478
43_I56_F0.673242.379
13_A66_A0.61562.176
8_G12_F0.570422.016
5_D62_Y0.56962.013
25_L29_G0.557811.971
34_G70_A0.507471.793
17_A30_A0.433651.533
10_G14_I0.428781.515
54_V57_L0.427331.510
17_A70_A0.423331.496
35_V66_A0.421311.489
43_I55_I0.39981.413
2_L6_A0.39071.381
9_L38_A0.383111.354
75_I78_R0.381361.348
43_I48_L0.374131.322
18_L22_R0.370771.310
21_L30_A0.368461.302
34_G66_A0.358511.267
60_E64_T0.357831.265
29_G40_G0.354751.254
6_A9_L0.354731.254
66_A70_A0.354441.253
61_I65_A0.338341.196
26_D29_G0.334441.182
19_K23_A0.329291.164
27_I74_F0.322841.141
15_S18_L0.314711.112
11_A15_S0.304211.075
31_I70_A0.301191.064
23_A36_I0.299751.059
5_D12_F0.298881.056
20_A33_L0.297351.051
5_D19_K0.29671.049
9_L36_I0.296641.048
61_I64_T0.292691.034
54_V58_R0.292151.032
29_G49_L0.288971.021
13_A17_A0.288871.021
7_I11_A0.284671.006
9_L12_F0.284221.004
8_G42_G0.278730.985
65_A69_G0.27790.982
17_A34_G0.277470.981
67_I71_L0.276710.978
27_I31_I0.27590.975
17_A73_Y0.272590.963
35_V63_A0.271490.959
15_S37_T0.270520.956
29_G33_L0.269590.953
58_R61_I0.267840.947
18_L40_G0.267380.945
55_I74_F0.262510.928
2_L61_I0.262420.927
55_I62_Y0.256830.908
35_V67_I0.255660.904
47_V72_A0.255290.902
31_I35_V0.254390.899
33_L37_T0.25250.892
31_I67_I0.252340.892
23_A44_L0.252210.891
9_L55_I0.249410.881
30_A74_F0.245190.867
48_L56_F0.24270.858
5_D69_G0.241050.852
13_A44_L0.237520.839
35_V39_V0.234280.828
20_A25_L0.230450.814
14_I73_Y0.229720.812
16_G20_A0.229570.811
20_A30_A0.228730.808
30_A34_G0.227980.806
6_A65_A0.227340.803
51_R57_L0.226450.800
9_L66_A0.225460.797
39_V55_I0.222980.788
28_F31_I0.222940.788
69_G73_Y0.221640.783
12_F15_S0.221050.781
6_A30_A0.218140.771
72_A76_F0.217810.770
36_I40_G0.215050.760
22_R26_D0.213240.754
39_V63_A0.213150.753
30_A62_Y0.210850.745
73_Y77_Y0.209590.741
52_T57_L0.208530.737
21_L77_Y0.20570.727
11_A69_G0.205440.726
39_V66_A0.20480.724
38_A42_G0.203270.718
26_D33_L0.20220.715
9_L56_F0.202130.714
68_I71_L0.200330.708
11_A26_D0.19510.690
21_L24_G0.190350.673
60_E63_A0.188090.665
40_G49_L0.187710.663
8_G48_L0.185530.656
6_A10_G0.181890.643
19_K33_L0.178540.631
22_R28_F0.177630.628
50_G54_V0.177420.627
10_G38_A0.177180.626
17_A74_F0.176880.625
24_G64_T0.175780.621
71_L78_R0.175340.620
15_S70_A0.17420.616
12_F16_G0.173990.615
32_V36_I0.173940.615
43_I57_L0.173760.614
4_L33_L0.172760.611
24_G76_F0.171890.607
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1vfgA0.637519.60.877
3h38A0.7125150.883
3t7lA0.4758.50.895
1miwA0.687580.895
1ou5A0.8754.40.907
3giaA0.753.30.912
3cx5I0.4252.50.917
1rmkA0.38751.60.925
3iyzA11.60.925
3aqlA0.81251.50.925
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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