GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
AzlC - AzlC protein
Pfam: PF03591 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 143
Sequences: 1289
Seq/Len: 9.01
HH_delta: 0.947 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
24_S27_E0.48343.172
29_I133_A0.412622.707
33_L129_V0.369172.422
18_A28_A0.361632.373
93_F121_G0.351062.303
31_M44_A0.34172.242
43_V64_V0.326362.141
74_S99_F0.300941.975
11_G131_G0.300851.974
37_A65_N0.296441.945
32_S132_T0.28711.884
30_L34_L0.287061.884
37_A68_H0.279931.837
14_F41_Q0.275531.808
25_W136_A0.268121.759
47_L52_A0.250131.641
7_Y95_T0.243911.600
3_I124_L0.243571.598
7_Y124_L0.243531.598
29_I129_V0.243191.596
92_F125_Y0.242451.591
31_M35_V0.239451.571
43_V60_T0.222941.463
36_F95_T0.222241.458
84_R88_L0.221131.451
37_A61_V0.220451.446
125_Y129_V0.217081.424
10_F124_L0.211271.386
37_A40_A0.209441.374
89_L125_Y0.208281.367
21_A45_V0.204321.341
96_D128_W0.202261.327
98_S124_L0.196991.293
127_S131_G0.192361.262
7_Y10_F0.188891.239
68_H94_L0.186051.221
45_V49_A0.184611.211
19_V136_A0.183481.204
53_S56_A0.181881.193
4_A127_S0.177691.166
71_Y99_F0.17651.158
35_V40_A0.176061.155
19_V29_I0.1761.155
75_L94_L0.173711.140
68_H97_E0.173171.136
14_F18_A0.172681.133
14_F42_F0.171971.128
99_F103_M0.171011.122
38_G96_D0.170461.118
85_W89_L0.165641.087
14_F132_T0.165381.085
98_S120_L0.161671.061
66_L69_L0.161071.057
36_F129_V0.157041.030
54_L58_A0.156731.028
12_I134_L0.155351.019
44_A61_V0.155071.017
32_S41_Q0.155051.017
36_F68_H0.154511.014
83_S86_K0.153931.010
41_Q132_T0.153251.006
11_G38_G0.152991.004
105_R108_P0.152731.002
14_F45_V0.151750.996
82_L86_K0.151490.994
36_F125_Y0.150620.988
9_P94_L0.149730.982
44_A48_L0.147930.971
38_G128_W0.147760.970
93_F125_Y0.147610.969
11_G96_D0.146550.962
130_L133_A0.14640.961
8_I11_G0.146340.960
78_Y142_I0.146190.959
133_A137_L0.14570.956
86_K118_L0.145630.956
55_L59_L0.145570.955
9_P100_A0.144680.949
109_N142_I0.144530.948
8_I12_I0.144350.947
122_L126_L0.14410.946
4_A130_L0.143020.938
39_A43_V0.142540.935
14_F28_A0.141910.931
6_G97_E0.141320.927
28_A136_A0.141050.925
8_I131_G0.140330.921
102_A120_L0.13970.917
87_R91_A0.139020.912
6_G101_V0.138610.909
72_G75_L0.137920.905
47_L60_T0.137710.904
6_G124_L0.137660.903
70_L97_E0.137640.903
6_G95_T0.137030.899
39_A64_V0.136990.899
1_L5_L0.136970.899
10_F70_L0.136710.897
14_F63_L0.13670.897
1_L30_L0.136490.896
33_L125_Y0.136140.893
9_P13_A0.135970.892
116_Y119_G0.135910.892
9_P66_L0.13560.890
23_F31_M0.135070.886
17_L41_Q0.134470.882
97_E128_W0.13440.882
73_A77_P0.134330.881
39_A96_D0.133510.876
59_L98_S0.132270.868
129_V137_L0.131490.863
79_L83_S0.131060.860
89_L93_F0.130320.855
9_P68_H0.129750.851
11_G128_W0.129040.847
86_K115_A0.126840.832
1_L23_F0.126210.828
46_G49_A0.125980.827
25_W28_A0.125820.826
19_V24_S0.125780.825
46_G50_A0.125610.824
56_A74_S0.125170.821
37_A64_V0.12490.820
6_G20_E0.123350.809
85_W88_L0.123290.809
75_L113_R0.122930.807
29_I136_A0.12280.806
11_G39_A0.122280.802
13_A62_L0.121710.799
61_V138_L0.121640.798
53_S57_I0.121250.796
78_Y106_F0.121220.795
17_L45_V0.120980.794
21_A49_A0.120330.790
68_H71_Y0.119660.785
17_L125_Y0.119110.782
32_S128_W0.118760.779
26_W134_L0.118180.775
28_A54_L0.117770.773
8_I130_L0.117260.769
97_E100_A0.117250.769
71_Y87_R0.11720.769
5_L31_M0.117190.769
71_Y92_F0.117130.769
41_Q95_T0.117060.768
57_I61_V0.116490.764
71_Y101_V0.116220.763
40_A61_V0.115750.759
99_F124_L0.115680.759
15_G135_G0.115210.756
35_V61_V0.114880.754
98_S121_G0.114760.753
122_L141_L0.114540.752
7_Y36_F0.114280.750
9_P79_L0.114250.750
10_F97_E0.113970.748
18_A24_S0.113870.747
30_L123_L0.113820.747
107_Q110_P0.113630.746
3_I97_E0.113610.745
46_G51_G0.113390.744
74_S140_N0.112710.740
13_A124_L0.112570.739
8_I134_L0.11230.737
59_L117_Y0.112050.735
45_V132_T0.112030.735
32_S39_A0.111930.734
105_R109_N0.111760.733
5_L79_L0.111580.732
31_M127_S0.111280.730
39_A128_W0.111210.730
71_Y94_L0.111190.730
41_Q129_V0.111130.729
46_G66_L0.110910.728
106_F130_L0.110860.727
128_W135_G0.110740.727
85_W130_L0.110330.724
57_I109_N0.110270.724
21_A35_V0.110230.723
8_I25_W0.109860.721
121_G124_L0.109790.720
13_A142_I0.109240.717
113_R140_N0.108520.712
11_G36_F0.108160.710
18_A33_L0.108020.709
102_A117_Y0.107910.708
3_I92_F0.107740.707
44_A58_A0.107730.707
25_W133_A0.107660.706
3_I45_V0.107660.706
35_V71_Y0.107250.704
60_T143_P0.106620.700
16_V103_M0.106560.699
85_W126_L0.106430.698
3_I64_V0.106280.697
61_V71_Y0.106090.696
35_V62_L0.105960.695
22_G91_A0.105890.695
29_I131_G0.105250.691
12_I126_L0.105120.690
7_Y13_A0.10490.688
111_P116_Y0.104890.688
104_S108_P0.104830.688
22_G138_L0.104470.685
1_L55_L0.103870.682
10_F116_Y0.103830.681
50_A53_S0.103580.680
52_A57_I0.10350.679
74_S77_P0.103160.677
43_V70_L0.103060.676
6_G107_Q0.102480.672
59_L137_L0.102470.672
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4eneA0.63645.40.947
4dncD0.25873.40.952
3zuxA0.67832.90.953
1otsA0.63642.90.953
3h9mA0.51051.60.959
3effK0.41261.40.96
2wwbA0.34271.20.961
3nd0A0.69931.10.963
1c2yA0.31470.90.964
1vf5F0.18880.90.964
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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