GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF308 - Short repeat of unknown function (DUF308)
Pfam: PF03729 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 72
Sequences: 1763
Seq/Len: 24.49
HH_delta: 0.807 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
33_I67_G0.726942.902
54_W58_L0.690242.756
43_A57_L0.662722.646
36_G60_G0.639732.554
40_L60_G0.586132.340
6_F31_W0.548212.189
43_A60_G0.515472.058
11_I15_F0.507082.025
26_I30_I0.484751.935
30_I34_I0.468811.872
13_L20_S0.438071.749
43_A53_W0.408281.630
53_W57_L0.393941.573
36_G64_I0.389651.556
36_G63_S0.382781.528
57_L61_I0.364321.455
63_S66_L0.330851.321
31_W35_S0.313351.251
36_G67_G0.312851.249
36_G40_L0.307531.228
32_L66_L0.305751.221
37_I41_I0.297391.187
12_L16_N0.295521.180
39_Q60_G0.293411.171
8_V12_L0.288891.153
2_S35_S0.288151.150
29_G67_G0.284081.134
28_L32_L0.278851.113
47_R53_W0.275121.098
55_W59_S0.266241.063
21_L25_A0.264081.054
32_L70_L0.26011.038
20_S32_L0.257151.027
25_A70_L0.257051.026
61_I65_V0.255931.022
65_V69_I0.245590.981
50_S53_W0.245490.980
6_F63_S0.236390.944
44_F57_L0.235610.941
32_L64_I0.231910.926
8_V11_I0.220560.881
56_S59_S0.212860.850
30_I45_R0.211430.844
28_L70_L0.211320.844
22_A26_I0.209760.837
38_F42_S0.209270.836
9_L21_L0.20860.833
2_S6_F0.207960.830
13_L25_A0.206430.824
35_S39_Q0.203560.813
3_G22_A0.200160.799
52_G55_W0.196290.784
13_L24_L0.195590.781
9_L31_W0.193130.771
24_L31_W0.192940.770
9_L27_I0.191890.766
27_I39_Q0.189130.755
21_L35_S0.189060.755
29_G33_I0.187820.750
33_I64_I0.187470.748
27_I31_W0.18690.746
41_I47_R0.186830.746
66_L70_L0.184480.737
29_G70_L0.18170.725
22_A70_L0.178660.713
41_I51_K0.178110.711
6_F9_L0.176280.704
40_L57_L0.175310.700
65_V68_I0.174540.697
6_F39_Q0.171560.685
42_S60_G0.170770.682
18_D22_A0.170270.680
46_R50_S0.16970.678
25_A32_L0.168810.674
47_R58_L0.164960.659
4_I61_I0.164670.657
28_L48_K0.164150.655
17_P24_L0.163920.654
2_S51_K0.163160.651
40_L44_F0.162830.650
36_G70_L0.162390.648
24_L63_S0.162130.647
25_A29_G0.161720.646
19_A69_I0.161690.646
56_S69_I0.16110.643
28_L35_S0.160560.641
10_G19_A0.160040.639
40_L64_I0.159990.639
57_L62_L0.159580.637
5_L56_S0.159030.635
13_L21_L0.158510.633
35_S63_S0.156750.626
3_G7_I0.156530.625
4_I8_V0.154010.615
50_S66_L0.153890.614
18_D21_L0.152340.608
23_A37_I0.152190.608
12_L15_F0.151320.604
33_I39_Q0.151170.604
42_S54_W0.15030.600
54_W65_V0.148680.594
53_W62_L0.145910.583
23_A29_G0.145720.582
4_I7_I0.145530.581
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4dx5A16.20.807
2v50A15.90.81
3w9iA15.80.81
3ne5A14.30.82
2w3zA0.40283.60.828
2jwaA0.61113.50.828
3aqpA13.10.832
3giaA0.916730.832
3owqA0.45832.90.835
3pjzA0.97222.80.836
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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