GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF307 - Domain of unknown function (DUF307)
Pfam: PF03733 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 53
Sequences: 949
Seq/Len: 17.91
HH_delta: 0.892 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
27_C36_G1.209093.725
23_G40_F1.041843.209
29_T32_G0.932142.871
19_W39_C0.718432.213
38_Q41_K0.718292.213
20_L43_A0.612321.886
16_A47_L0.60161.853
8_F48_W0.545291.680
1_L5_I0.532271.640
8_F47_L0.529611.631
11_F14_W0.507981.565
13_W17_L0.4891.506
23_G27_C0.484921.494
9_I13_W0.484331.492
27_C33_I0.462891.426
44_G52_K0.43851.351
26_C35_Y0.416941.284
21_L25_L0.386481.191
27_C40_F0.364741.124
4_N51_G0.359871.109
25_L29_T0.352841.087
30_I34_P0.351661.083
11_F15_L0.348931.075
15_L46_L0.321920.992
26_C32_G0.321340.990
17_L21_L0.316860.976
16_A20_L0.307090.946
37_I41_K0.306220.943
27_C37_I0.303830.936
15_L42_L0.301160.928
35_Y45_Y0.294250.906
22_A39_C0.289260.891
19_W42_L0.288960.890
34_P38_Q0.278780.859
17_L20_L0.277490.855
42_L45_Y0.269810.831
50_F53_E0.269070.829
5_I9_I0.268190.826
39_C52_K0.26760.824
31_I34_P0.264540.815
6_L10_F0.261260.805
23_G36_G0.259950.801
14_W18_I0.258380.796
45_Y50_F0.257810.794
22_A26_C0.252840.779
1_L48_W0.234940.724
20_L24_I0.225610.695
24_I28_I0.223890.690
35_Y38_Q0.22270.686
26_C39_C0.220770.680
11_F22_A0.218510.673
33_I36_G0.216340.666
3_G32_G0.21390.659
46_L50_F0.211570.652
15_L18_I0.209890.647
7_W43_A0.202980.625
10_F14_W0.202980.625
4_N7_W0.202610.624
35_Y39_C0.201760.622
39_C50_F0.197780.609
8_F50_F0.197330.608
22_A48_W0.197290.608
26_C29_T0.194360.599
41_K45_Y0.193530.596
25_L28_I0.18750.578
11_F20_L0.187080.576
3_G50_F0.186420.574
32_G41_K0.184890.570
6_L21_L0.184210.567
4_N50_F0.182910.563
7_W23_G0.180430.556
35_Y46_L0.179750.554
1_L21_L0.178020.548
8_F52_K0.177220.546
30_I33_I0.173890.536
9_I28_I0.173340.534
1_L6_L0.1720.530
18_I46_L0.169280.521
24_I37_I0.168990.521
25_L52_K0.168960.520
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3n58A0.33961.90.892
1xsqA0.35851.60.896
4dweA0.54721.30.901
4geqB0.33961.10.904
3tguG0.415110.908
1pp9G0.41510.90.909
3d2fA0.50940.80.911
2c9kA0.79250.80.911
3bz1X0.67920.80.912
1ximA0.52830.80.912
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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