GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Competence - Competence protein
Pfam: PF03772 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 271
Sequences: 1870
Seq/Len: 6.9
HH_delta: 0.96 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
17_F230_L0.408013.569
27_A77_S0.323572.830
108_A128_F0.305142.669
125_Q175_Y0.294732.578
69_A82_F0.292232.556
66_L86_S0.278622.437
69_A78_V0.276672.420
62_L86_S0.274342.400
134_I160_I0.267912.344
133_G167_A0.261132.284
40_L64_F0.259992.274
111_I118_S0.252552.209
70_L74_F0.249612.183
75_S78_V0.247322.163
100_P135_I0.245392.147
69_A74_F0.236782.071
84_M107_A0.23252.034
133_G164_A0.230582.017
107_A128_F0.227011.986
66_L82_F0.220841.932
111_I128_F0.215481.885
10_S13_L0.213981.872
79_L111_I0.211691.852
16_D234_S0.21151.850
31_L34_G0.198971.740
164_A168_T0.197471.727
104_L132_F0.196531.719
25_L190_V0.189981.662
65_L82_F0.189681.659
137_F163_A0.18511.619
6_R27_A0.183081.601
27_A81_A0.181431.587
122_I175_Y0.181321.586
25_L191_V0.179831.573
126_L172_L0.178951.565
130_A168_T0.178621.562
28_I78_V0.177111.549
198_I225_L0.176651.545
182_I239_L0.175011.531
83_I107_A0.170711.493
14_K23_S0.169951.487
20_L236_F0.166231.454
27_A32_H0.164681.441
23_S27_A0.16221.419
33_V65_L0.159271.393
231_W234_S0.157011.373
36_I40_L0.155831.363
193_L228_L0.154151.348
6_R81_A0.153811.345
15_E19_D0.152821.337
31_L191_V0.151491.325
182_I240_P0.149821.311
44_L60_I0.149431.307
77_S123_G0.149411.307
108_A124_F0.148941.303
17_F26_L0.148811.302
217_L220_Y0.14871.301
6_R28_I0.147451.290
190_V229_L0.147131.287
16_D233_L0.145871.276
13_L17_F0.144711.266
189_I192_P0.143931.259
37_A85_L0.143171.252
20_L233_L0.140241.227
26_L32_H0.139051.216
19_D243_S0.136811.197
38_G41_Y0.136021.190
129_L171_L0.135881.189
200_P204_L0.135121.182
28_I33_V0.135031.181
33_V82_F0.134761.179
52_P56_I0.13421.174
103_S107_A0.133861.171
220_Y224_F0.132961.163
104_L108_A0.132471.159
91_G98_I0.131211.148
186_A236_F0.130751.144
62_L66_L0.129311.131
182_I241_F0.128991.128
168_T172_L0.128851.127
34_G38_G0.127821.118
141_L163_A0.127191.113
131_V135_I0.12711.112
101_L136_L0.126431.106
189_I232_L0.12481.092
38_G42_W0.124251.087
107_A111_I0.123921.084
42_W46_R0.123851.083
105_A109_L0.123341.079
125_Q161_S0.123031.076
91_G94_F0.122551.072
13_L230_L0.122491.071
22_L233_L0.122091.068
161_S165_Q0.121441.062
112_L118_S0.120311.052
91_G103_S0.120151.051
235_F239_L0.119271.043
6_R31_L0.118691.038
224_F228_L0.118611.038
227_N231_W0.118491.036
168_T175_Y0.118191.034
67_F71_L0.117781.030
88_S92_K0.117491.028
28_I72_T0.117311.026
194_F229_L0.11721.025
5_D8_E0.116741.021
25_L132_F0.116471.019
69_A77_S0.116381.018
18_Q23_S0.116341.018
20_L186_A0.116221.017
3_L72_T0.11591.014
89_L134_I0.115811.013
236_F239_L0.115621.011
110_I114_L0.11561.011
118_S121_S0.115561.011
27_A130_A0.115351.009
31_L187_N0.115231.008
229_L233_L0.115231.008
187_N191_V0.115061.006
15_E18_Q0.114611.003
74_F82_F0.11431.000
250_S253_I0.113370.992
133_G163_A0.113140.990
182_I236_F0.112920.988
177_G248_K0.112810.987
205_A219_L0.112540.984
72_T78_V0.112470.984
19_D242_S0.112330.983
191_V195_S0.112020.980
62_L203_L0.11130.974
173_L246_F0.111050.971
231_W235_F0.11070.968
177_G247_G0.110320.965
101_L132_F0.110150.964
87_L107_A0.109970.962
22_L186_A0.108870.952
19_D237_A0.108670.951
31_L195_S0.108610.950
17_F22_L0.108570.950
237_A240_P0.108110.946
55_K95_G0.107570.941
182_I242_S0.107450.940
102_N106_L0.107290.939
152_L221_L0.107230.938
211_F214_L0.107080.937
14_K18_Q0.107050.936
86_S90_L0.105370.922
206_L209_S0.105290.921
45_R57_A0.105160.920
169_L183_S0.105140.920
32_H195_S0.104890.918
2_L202_L0.104220.912
217_L221_L0.104150.911
201_L221_L0.103820.908
99_S102_N0.103730.907
124_F164_A0.103440.905
76_P118_S0.103060.902
164_A167_A0.103020.901
195_S198_I0.102920.900
119_L125_Q0.102290.895
76_P121_S0.102210.894
84_M131_V0.102070.893
210_L213_P0.101280.886
28_I187_N0.101120.885
178_S243_S0.100270.877
22_L191_V0.100040.875
115_N118_S0.099970.874
62_L89_L0.099960.874
211_F244_I0.099630.871
9_L124_F0.099520.871
45_R60_I0.099420.870
115_N175_Y0.099140.867
120_F125_Q0.099060.867
26_L161_S0.098780.864
123_G167_A0.098640.863
109_L207_L0.098630.863
71_L172_L0.09840.861
115_N123_G0.097920.857
76_P164_A0.09760.854
27_A123_G0.097460.853
32_H75_S0.09710.849
91_G105_A0.096940.848
78_V82_F0.09650.844
38_G61_A0.096350.843
125_Q176_F0.096350.843
20_L130_A0.09620.841
20_L194_F0.096170.841
31_L75_S0.096090.841
137_F164_A0.096080.840
206_L210_L0.096070.840
44_L47_L0.095960.839
41_Y45_R0.09580.838
76_P111_I0.095790.838
133_G169_L0.095590.836
83_I111_I0.095490.835
3_L71_L0.095270.833
196_F200_P0.095260.833
171_L175_Y0.095220.833
24_H187_N0.095170.832
160_I164_A0.095170.832
169_L172_L0.0950.831
14_K72_T0.094890.830
81_A195_S0.09470.828
79_L107_A0.094350.825
161_S164_A0.094240.824
127_S192_P0.094030.823
122_I176_F0.093880.821
23_S26_L0.093330.816
5_D127_S0.093290.816
113_L207_L0.093280.816
203_L252_W0.093230.816
197_I225_L0.092590.810
13_L63_L0.092550.810
126_L171_L0.092380.808
19_D181_L0.092150.806
6_R32_H0.092020.805
6_R23_S0.091890.804
200_P208_L0.091730.802
18_Q187_N0.091680.802
81_A89_L0.091360.799
149_I152_L0.091310.799
16_D237_A0.091210.798
193_L198_I0.090540.792
228_L232_L0.090290.790
215_A218_L0.090020.787
134_I247_G0.089620.784
1_L194_F0.089550.783
8_E113_L0.089230.781
82_F86_S0.089180.780
61_A65_L0.089120.780
139_P142_K0.088690.776
181_L240_P0.08860.775
12_E42_W0.088480.774
123_G187_N0.088330.773
179_I253_I0.088270.772
36_I64_F0.088160.771
53_P57_A0.088040.770
12_E15_E0.088010.770
140_P144_L0.08790.769
146_Q149_I0.087880.769
27_A124_F0.087780.768
179_I213_P0.087750.768
126_L165_Q0.087450.765
178_S181_L0.087410.765
60_I207_L0.087390.764
11_P15_E0.087370.764
110_I197_I0.087240.763
40_L44_L0.087090.762
26_L95_G0.08690.760
181_L244_I0.086890.760
162_L184_I0.086770.759
67_F90_L0.086730.759
58_F92_K0.086580.757
24_H29_S0.086570.757
224_F227_N0.086470.756
27_A172_L0.086120.753
1_L236_F0.086050.753
193_L232_L0.085960.752
24_H30_G0.085720.750
28_I31_L0.085610.749
20_L131_V0.085530.748
139_P167_A0.085330.746
91_G96_R0.085330.746
99_S126_L0.084670.741
115_N135_I0.084560.740
57_A61_A0.084550.740
81_A134_I0.084470.739
27_A127_S0.08440.738
72_T75_S0.084380.738
137_F185_L0.084370.738
112_L124_F0.084090.736
25_L183_S0.083940.734
77_S81_A0.083930.734
78_V180_S0.083750.733
90_L204_L0.083630.732
21_G228_L0.083590.731
194_F198_I0.082950.726
36_I160_I0.082790.724
76_P123_G0.082710.723
136_L215_A0.082470.721
132_F136_L0.08220.719
201_L204_L0.081930.717
205_A224_F0.081870.716
102_N105_A0.081810.716
75_S203_L0.081770.715
208_L250_S0.081770.715
185_L188_L0.081720.715
36_I195_S0.081580.714
143_R227_N0.081570.714
147_K151_K0.081530.713
235_F238_S0.081280.711
36_I71_L0.081190.710
32_H192_P0.081180.710
87_L250_S0.081180.710
107_A129_L0.081110.709
59_I114_L0.081090.709
76_P122_I0.080960.708
150_K153_R0.08050.704
38_G55_K0.080410.703
25_L31_L0.08040.703
77_S161_S0.08030.702
177_G226_L0.080290.702
32_H65_L0.080240.702
87_L110_I0.08020.702
138_Y160_I0.080160.701
205_A230_L0.080130.701
57_A60_I0.080120.701
177_G194_F0.08010.701
101_L109_L0.080010.700
136_L139_P0.079890.699
221_L224_F0.079560.696
115_N121_S0.079560.696
52_P55_K0.079460.695
145_L204_L0.079430.695
172_L183_S0.07940.695
12_E47_L0.079390.694
115_N161_S0.079340.694
25_L194_F0.079280.693
8_E15_E0.079270.693
85_L118_S0.079220.693
65_L76_P0.078870.690
131_V191_V0.078810.689
245_W248_K0.078780.689
220_Y232_L0.078760.689
223_D227_N0.078490.687
126_L168_T0.078360.685
22_L182_I0.077920.682
74_F125_Q0.077810.681
249_P253_I0.077770.680
223_D226_L0.077660.679
227_N234_S0.077650.679
51_G55_K0.077610.679
104_L130_A0.077570.679
134_I163_A0.077510.678
247_G253_I0.077490.678
123_G209_S0.077480.678
104_L135_I0.077370.677
169_L173_L0.077330.676
44_L57_A0.077290.676
114_L217_L0.077160.675
32_H81_A0.0770.674
28_I32_H0.076980.673
71_L138_Y0.076930.673
1_L226_L0.076850.672
72_T165_Q0.076610.670
140_P145_L0.07650.669
149_I153_R0.076440.669
38_G174_Y0.07640.668
217_L231_W0.076350.668
68_Y202_L0.076330.668
184_I187_N0.076260.667
122_I126_L0.076180.666
122_I125_Q0.076160.666
32_H68_Y0.075920.664
241_F250_S0.075920.664
151_K227_N0.075880.664
43_L228_L0.075870.664
3_L36_I0.075830.663
21_G30_G0.075740.663
64_F166_L0.075730.662
36_I203_L0.075720.662
37_A122_I0.075710.662
28_I77_S0.075710.662
6_R65_L0.075620.661
72_T99_S0.075620.661
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2infA0.221490.96
4exqA0.22515.80.963
3qkgA0.23624.80.964
3c1lA0.22144.20.965
2pfxA0.22144.20.965
2oyoA0.22144.10.965
2uz0A0.22143.80.966
3v57A0.23993.70.966
2hm7A0.22143.60.966
3u0vA0.22143.50.966
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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