GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF333 - Domain of unknown function (DUF333)
Pfam: PF03891 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 50
Sequences: 245
Seq/Len: 4.9
HH_delta: 0.861 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
40_C48_G0.396762.447
22_K28_Q0.383062.362
40_C50_C0.324922.004
19_E33_V0.306091.888
8_S42_E0.290981.795
33_V39_R0.275511.699
6_P43_W0.264991.634
45_L49_D0.254571.570
18_L42_E0.252971.560
45_L48_G0.246631.521
5_N8_S0.22221.370
26_G42_E0.219761.355
38_R48_G0.219141.351
18_L41_E0.218831.350
4_A47_R0.211151.302
43_W47_R0.204471.261
20_I30_G0.196591.212
9_V13_E0.195651.207
5_N43_W0.195391.205
4_A9_V0.191871.183
9_V12_V0.189041.166
10_Y23_Q0.185991.147
5_N47_R0.184911.140
8_S20_I0.181051.117
16_G42_E0.178131.099
23_Q29_V0.178011.098
8_S41_E0.168091.037
31_Y39_R0.157240.970
8_S16_G0.150560.929
20_I31_Y0.146670.905
34_L40_C0.144910.894
2_G25_D0.142220.877
18_L34_L0.141690.874
30_G42_E0.141380.872
16_G45_L0.140210.865
21_R38_R0.139950.863
3_M25_D0.139770.862
24_P38_R0.137140.846
17_K36_D0.133570.824
35_P49_D0.130330.804
5_N41_E0.13020.803
36_D40_C0.12920.797
23_Q31_Y0.127990.789
19_E41_E0.123880.764
29_V41_E0.120350.742
14_Q45_L0.119780.739
13_E46_Y0.119770.739
10_Y38_R0.119340.736
1_V22_K0.118450.730
8_S47_R0.118430.730
21_R24_P0.117990.728
24_P31_Y0.117360.724
10_Y45_L0.114090.704
6_P9_V0.113070.697
13_E25_D0.113010.697
7_A47_R0.111490.688
4_A7_A0.110810.683
16_G34_L0.110460.681
20_I28_Q0.110320.680
10_Y40_C0.110040.679
1_V25_D0.10930.674
4_A14_Q0.107610.664
28_Q34_L0.107560.663
41_E47_R0.107470.663
21_R39_R0.107090.660
1_V24_P0.106470.657
44_A48_G0.105940.653
23_Q39_R0.10470.646
7_A41_E0.102470.632
3_M9_V0.1010.623
12_V31_Y0.100960.623
3_M37_G0.100650.621
7_A43_W0.099770.615
8_S43_W0.09970.615
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3fh1A0.8425.30.861
2hevF0.6216.10.872
3idbB114.90.874
3tnpB111.40.88
3shrA190.885
3fgrA18.60.886
3dlqR0.768.30.886
3k0zA0.888.30.886
3qt4A0.688.20.886
3hk4A0.87.90.888
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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