GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF350 - Domain of Unknown Function (DUF350)
Pfam: PF03994 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 54
Sequences: 810
Seq/Len: 15
HH_delta: 0.842 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
27_E32_N0.595582.847
23_D26_E0.522792.499
26_E30_K0.445722.130
12_G46_I0.430112.056
28_I36_A0.318111.520
36_A40_A0.299091.429
48_L51_A0.287141.372
4_V8_L0.273931.309
5_G50_I0.260931.247
5_G54_I0.259491.240
1_Y53_A0.257231.229
12_G42_I0.257081.229
37_I40_A0.245351.173
28_I35_A0.244551.169
38_V41_G0.238091.138
10_L14_F0.233421.116
9_L13_F0.230641.102
25_R48_L0.228481.092
47_G50_I0.225381.077
8_L46_I0.220921.056
7_V41_G0.212071.014
41_G48_L0.211911.013
46_I49_I0.210691.007
13_F24_L0.210061.004
28_I54_I0.208950.999
11_L33_V0.208430.996
16_F42_I0.208030.994
3_L10_L0.205130.980
8_L53_A0.204120.976
44_I48_L0.203560.973
13_F19_L0.202640.968
1_Y5_G0.199240.952
27_E34_A0.197860.946
3_L18_L0.197690.945
40_A50_I0.196520.939
1_Y54_I0.195470.934
16_F49_I0.194860.931
7_V11_L0.191220.914
14_F18_L0.19110.913
16_F21_P0.190230.909
19_L51_A0.188920.903
9_L46_I0.18740.896
8_L24_L0.186530.892
17_D38_V0.186150.890
40_A44_I0.186120.890
9_L47_G0.184030.880
17_D24_L0.182370.872
6_I14_F0.182070.870
8_L37_I0.181330.867
15_V28_I0.181030.865
2_G9_L0.17920.856
20_T24_L0.175840.840
40_A47_G0.175670.840
31_G34_A0.174460.834
6_I11_L0.173730.830
36_A39_L0.171760.821
32_N36_A0.170030.813
7_V33_V0.169210.809
26_E29_K0.168330.805
11_L15_V0.166430.795
1_Y31_G0.162790.778
8_L13_F0.162130.775
28_I32_N0.162050.775
19_L49_I0.160060.765
18_L39_L0.15870.758
13_F43_F0.157930.755
47_G51_A0.157560.753
10_L28_I0.157150.751
17_D54_I0.157080.751
5_G47_G0.156530.748
2_G52_A0.155530.743
6_I41_G0.155150.742
19_L23_D0.154710.739
15_V18_L0.15370.735
16_F46_I0.153340.733
4_V52_A0.152560.729
18_L44_I0.150820.721
47_G52_A0.14910.713
6_I10_L0.148980.712
4_V50_I0.148750.711
27_E35_A0.148690.711
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1rh1A0.5375.30.842
4av3A0.98154.10.85
2wswA12.90.86
4iu9B0.55562.80.86
3ayfA0.98152.80.861
4ainA12.70.861
2yiuB0.62962.40.865
1zrtD0.59262.30.866
1qleD0.33332.20.868
1m56D0.33332.10.868
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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