GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
MnhB - Domain related to MnhB subunit of NaH antiporter
Pfam: PF04039 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 124
Sequences: 877
Seq/Len: 7.07
HH_delta: 0.94 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
19_G113_K0.674165.387
22_L39_I0.437953.499
19_G40_L0.28882.308
88_F91_N0.256132.047
16_L40_L0.228221.823
40_L113_K0.228151.823
72_L115_A0.226261.808
79_G89_F0.213821.708
87_W91_N0.201371.609
104_T107_N0.196581.571
5_R9_R0.195061.559
78_T107_N0.191591.531
94_L97_V0.191061.527
23_L110_V0.186331.489
21_Y39_I0.181831.453
28_L35_Q0.181411.449
79_G82_P0.17681.413
109_D116_V0.170781.365
37_G72_L0.170681.364
81_G104_T0.164761.316
15_I43_A0.161541.291
109_D113_K0.161291.289
28_L101_G0.159141.272
54_D70_I0.158431.266
70_I114_V0.156231.248
105_I109_D0.15541.242
12_F15_I0.1541.230
8_A50_A0.153251.224
95_P98_G0.152621.219
93_W99_S0.150081.199
9_R51_F0.14541.162
36_G42_A0.14271.140
2_P88_F0.14011.119
71_G109_D0.139561.115
79_G90_L0.138921.110
78_T81_G0.138231.104
4_L46_L0.138041.103
109_D112_V0.137371.098
80_I84_L0.13721.096
67_L114_V0.1371.095
114_V117_G0.13591.086
80_I83_L0.135721.084
77_A82_P0.134521.075
82_P88_F0.133171.064
35_Q41_A0.132761.061
82_P89_F0.132511.059
25_H29_S0.13141.050
25_H38_V0.131291.049
45_I110_V0.130861.046
104_T109_D0.130631.044
6_T51_F0.128391.026
27_H32_G0.126731.013
4_L86_G0.126711.012
36_G111_G0.126491.011
112_V116_V0.125671.004
97_V100_G0.125251.001
107_N110_V0.124690.996
29_S45_I0.124270.993
5_R51_F0.123250.985
38_V118_G0.122840.982
109_D118_G0.122830.981
75_A79_G0.122650.980
4_L43_A0.122580.979
12_F47_L0.121620.972
53_I123_I0.12070.964
89_F106_L0.120440.962
54_D58_K0.120.959
73_L80_I0.119580.955
45_I120_V0.119260.953
23_L111_G0.118750.949
72_L109_D0.118630.948
74_I105_I0.118440.946
15_I39_I0.117820.941
35_Q117_G0.116740.933
41_A57_R0.115850.926
3_I45_I0.115640.924
8_A115_A0.115370.922
87_W92_F0.114780.917
17_L54_D0.114750.917
8_A43_A0.114240.913
96_N99_S0.113680.908
13_P111_G0.113370.906
108_F118_G0.112730.901
13_P48_Y0.112460.899
83_L86_G0.112280.897
42_A55_A0.112170.896
48_Y69_G0.11180.893
7_V50_A0.111480.891
74_I77_A0.111210.889
104_T108_F0.111110.888
55_A59_F0.110230.881
107_N117_G0.109170.872
41_A122_F0.109150.872
53_I57_R0.108870.870
81_G107_N0.108680.868
16_L43_A0.107860.862
39_I53_I0.107380.858
40_L45_I0.107320.857
7_V73_L0.107120.856
62_W70_I0.106340.850
76_I83_L0.105960.847
22_L25_H0.105110.840
4_L50_A0.104940.838
76_I80_I0.104930.838
95_P99_S0.10490.838
46_L60_P0.104860.838
68_E72_L0.104610.836
41_A120_V0.104290.833
14_F63_K0.10380.829
67_L70_I0.103720.829
20_L54_D0.102680.820
12_F59_F0.102350.818
37_G52_G0.102220.817
47_L81_G0.102140.816
23_L27_H0.102010.815
63_K66_A0.1020.815
73_L121_I0.101170.808
7_V87_W0.100940.807
112_V118_G0.100860.806
8_A66_A0.100710.805
5_R72_L0.100070.800
9_R46_L0.099990.799
21_Y24_L0.099870.798
29_S39_I0.099760.797
20_L84_L0.099650.796
119_T123_I0.099650.796
45_I107_N0.099410.794
70_I84_L0.099280.793
44_F50_A0.099040.791
16_L54_D0.098630.788
7_V84_L0.097980.783
70_I73_L0.097710.781
42_A59_F0.097550.779
54_D66_A0.097080.776
42_A64_L0.096850.774
92_F102_L0.096650.772
78_T89_F0.096640.772
3_I14_F0.096640.772
48_Y121_I0.096520.771
21_Y67_L0.096260.769
71_G79_G0.096230.769
15_I18_F0.096130.768
27_H104_T0.096070.768
16_L85_F0.096060.768
73_L83_L0.096050.767
2_P60_P0.09550.763
88_F118_G0.095320.762
47_L55_A0.095110.760
12_F51_F0.094920.758
113_K117_G0.094870.758
28_L99_S0.094740.757
46_L106_L0.094540.755
114_V118_G0.09420.753
83_L89_F0.093960.751
108_F112_V0.093750.749
91_N105_I0.093660.748
65_I122_F0.093650.748
57_R63_K0.093550.747
37_G123_I0.093230.745
17_L59_F0.093130.744
77_A80_I0.093130.744
51_F61_P0.09280.741
3_I10_L0.09280.741
90_L116_V0.092770.741
2_P7_V0.092740.741
66_A83_L0.092490.739
36_G41_A0.092430.739
12_F50_A0.092430.739
66_A70_I0.092270.737
20_L76_I0.092130.736
68_E107_N0.092040.735
75_A109_D0.091670.732
46_L50_A0.091230.729
28_L103_I0.091030.727
71_G116_V0.090720.725
16_L103_I0.090680.725
19_G23_L0.090450.723
35_Q38_V0.090210.721
36_G50_A0.090210.721
78_T93_W0.089960.719
56_E66_A0.089730.717
25_H61_P0.089690.717
75_A116_V0.089290.713
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4i0uA0.49192.30.94
2iubA0.45161.80.944
4ev6A0.46771.60.945
1fftB0.51.50.946
1p58A0.43551.30.948
1qynA0.45971.30.948
2a65A0.91131.20.949
2l2tA0.33871.20.949
2f2bA0.95160.90.952
3p5nA0.54840.80.954
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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