GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Got1 - Got1Sft2-like family
Pfam: PF04178 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 118
Sequences: 542
Seq/Len: 4.59
HH_delta: 0.93 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
69_S92_F0.24482.245
48_K52_K0.240122.202
84_G88_L0.190591.748
66_Y97_L0.180721.658
77_A86_T0.179611.647
75_Y79_I0.17761.629
61_I65_I0.158081.450
47_P75_Y0.150961.385
41_T50_Q0.149291.369
34_N66_Y0.14911.368
47_P51_F0.147581.354
76_F80_L0.145891.338
74_L78_F0.145591.335
9_L31_T0.142941.311
57_P78_F0.142721.309
40_S99_W0.138831.273
50_Q54_M0.138591.271
81_K84_G0.138131.267
64_I68_I0.136171.249
100_Y104_Y0.130431.196
20_L38_L0.129451.187
53_F56_S0.129341.186
5_I9_L0.128071.175
51_F55_F0.126781.163
73_T93_Q0.125781.154
29_L38_L0.124521.142
44_L78_F0.12271.125
36_L90_S0.122391.123
16_L30_Y0.121561.115
9_L45_I0.121091.111
40_S63_T0.11981.099
7_F73_T0.119691.098
17_G53_F0.119511.096
17_G20_L0.119291.094
59_R100_Y0.118131.083
57_P60_L0.117821.081
74_L103_S0.11751.078
52_K114_K0.116691.070
95_P102_L0.116081.065
50_Q100_Y0.116071.065
59_R104_Y0.116021.064
23_P40_S0.115081.056
6_C9_L0.114871.054
55_F64_I0.114781.053
6_C17_G0.114711.052
22_F29_L0.114571.051
52_K58_K0.114381.049
60_L70_L0.114081.046
39_A51_F0.113821.044
107_F115_F0.113471.041
108_G112_L0.112871.035
17_G33_G0.11261.033
6_C87_L0.112151.029
24_R83_Y0.111841.026
40_S62_A0.111841.026
14_F35_I0.111181.020
83_Y90_S0.110821.016
10_S14_F0.110741.016
98_I102_L0.109291.002
64_I76_F0.109261.002
49_K88_L0.107450.986
10_S16_L0.107320.984
86_T111_G0.106950.981
59_R99_W0.106810.980
31_T59_R0.106330.975
8_F14_F0.106180.974
78_F90_S0.106120.973
63_T104_Y0.105890.971
8_F19_L0.104990.963
61_I87_L0.104940.963
67_F98_I0.104750.961
87_L98_I0.104160.955
5_I8_F0.104050.954
14_F17_G0.103890.953
81_K91_I0.103750.952
71_I79_I0.103730.951
18_V29_L0.103670.951
32_L98_I0.103650.951
13_F88_L0.103280.947
45_I53_F0.102690.942
99_W109_R0.102680.942
64_I71_I0.102530.940
37_F50_Q0.102480.940
30_Y45_I0.101990.935
18_V52_K0.101490.931
7_F20_L0.10140.930
33_G47_P0.101070.927
111_G114_K0.100960.926
42_F50_Q0.100740.924
63_T80_L0.100490.922
71_I109_R0.100310.920
23_P30_Y0.099960.917
13_F36_L0.099890.916
18_V97_L0.098860.907
100_Y103_S0.097710.896
85_L95_P0.097660.896
18_V66_Y0.097480.894
53_F104_Y0.097420.894
85_L102_L0.097180.891
68_I79_I0.097080.890
100_Y107_F0.096990.890
91_I96_A0.096950.889
9_L101_L0.09660.886
47_P52_K0.095790.879
15_F28_I0.095710.878
48_K51_F0.095640.877
54_M59_R0.095240.874
110_P113_K0.094980.871
8_F42_F0.094820.870
35_I72_L0.094580.867
73_T85_L0.09360.858
70_L99_W0.093560.858
80_L93_Q0.093470.857
35_I51_F0.093450.857
67_F71_I0.093120.854
13_F101_L0.093070.854
34_N62_A0.092920.852
93_Q99_W0.092230.846
59_R91_I0.090730.832
24_R32_L0.090250.828
10_S33_G0.090150.827
42_F65_I0.090070.826
29_L86_T0.090070.826
55_F72_L0.089980.825
10_S43_F0.089940.825
42_F47_P0.089890.824
15_F19_L0.089660.822
28_I32_L0.089540.821
60_L63_T0.089450.820
64_I113_K0.089390.820
60_L82_S0.089380.820
42_F87_L0.089130.817
10_S70_L0.089120.817
43_F87_L0.088950.816
65_I92_F0.08880.814
44_L52_K0.088560.812
10_S50_Q0.088260.810
31_T85_L0.087680.804
4_I7_F0.087570.803
15_F36_L0.087240.800
10_S17_G0.087090.799
42_F66_Y0.086950.797
36_L112_L0.086790.796
96_A103_S0.086730.795
31_T73_T0.086460.793
96_A100_Y0.08630.792
76_F86_T0.086250.791
104_Y107_F0.086030.789
45_I50_Q0.085710.786
62_A109_R0.085690.786
13_F16_L0.085320.783
41_T107_F0.085270.782
4_I103_S0.085130.781
68_I76_F0.084830.778
45_I101_L0.08460.776
49_K91_I0.084430.774
87_L102_L0.084110.771
23_P77_A0.083940.770
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4ev6A0.44077.40.93
4i0uA0.44075.30.934
4humA0.53393.20.941
2iubA0.44072.70.943
4kjrA0.99152.40.944
4kjsA0.99152.40.944
3j01A0.44921.30.951
3mk7A0.53391.30.952
3m73A0.55081.20.953
1bl1A0.25421.10.953
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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