GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
FxsA - FxsA cytoplasmic membrane protein
Pfam: PF04186 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 119
Sequences: 668
Seq/Len: 5.61
HH_delta: 0.912 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
24_F28_L0.367132.708
18_V85_F0.351032.589
14_V86_L0.320922.367
96_L99_V0.290672.144
76_G94_L0.285842.108
34_T91_G0.2762.036
69_D104_R0.271982.006
10_L86_L0.259531.914
7_Y87_T0.248281.831
13_A24_F0.231641.708
55_Q59_Q0.230771.702
78_V82_I0.229591.693
56_S61_E0.222271.639
76_G91_G0.215861.592
22_I26_W0.200721.480
31_V34_T0.195151.439
23_G27_T0.195061.439
42_L77_G0.189681.399
16_I19_G0.18881.392
86_L106_L0.186041.372
54_Q58_R0.183111.350
15_L31_V0.179221.322
21_W25_L0.179071.321
39_I81_I0.178521.317
69_D100_R0.175671.296
94_L99_V0.175071.291
22_I85_F0.172021.269
45_Q95_L0.171491.265
25_L29_L0.170431.257
51_R54_Q0.168821.245
77_G81_I0.164661.214
41_L95_L0.163571.206
30_L85_F0.163091.203
15_L77_G0.160641.185
33_L37_L0.160261.182
15_L85_F0.158961.172
89_I93_L0.158261.167
53_L71_A0.156291.153
49_A73_L0.152231.123
63_P87_T0.150881.113
70_G91_G0.150451.110
53_L72_L0.150171.108
99_V104_R0.146181.078
18_V42_L0.145681.074
72_L91_G0.145051.070
19_G23_G0.145021.070
101_R104_R0.144271.064
72_L94_L0.143831.061
30_L97_P0.142411.050
49_A52_R0.141141.041
48_R53_L0.140921.039
98_P102_L0.140221.034
15_L27_T0.139051.026
16_I22_I0.139041.025
93_L103_L0.138991.025
6_L82_I0.138951.025
110_R113_K0.136861.009
42_L73_L0.136191.004
69_D72_L0.133860.987
53_L67_L0.131150.967
33_L54_Q0.130620.963
9_I13_A0.129890.958
5_L8_P0.128990.951
39_I74_A0.12820.945
57_L60_G0.127980.944
53_L68_L0.126230.931
31_V91_G0.126120.930
34_T87_T0.125610.926
26_W37_L0.12460.919
105_R110_R0.124310.917
104_R110_R0.123650.912
70_G100_R0.123020.907
4_F95_L0.122290.902
37_L58_R0.122150.901
43_R80_L0.121420.895
19_G28_L0.121180.894
25_L106_L0.11880.876
12_I24_F0.117840.869
33_L50_L0.117770.869
29_L33_L0.117740.868
72_L103_L0.117680.868
73_L91_G0.117650.868
20_S32_I0.11710.864
4_F27_T0.116240.857
28_L108_M0.115570.852
42_L111_V0.114960.848
51_R55_Q0.114850.847
63_P70_G0.114470.844
55_Q109_K0.114150.842
46_G80_L0.114130.842
19_G24_F0.114040.841
3_L41_L0.113290.836
81_I89_I0.113020.834
72_L107_L0.112860.832
10_L13_A0.112610.831
43_R46_G0.111830.825
62_M90_L0.111660.823
18_V35_A0.111290.821
89_I92_L0.111230.820
102_L106_L0.111080.819
65_E69_D0.110950.818
6_L39_I0.110370.814
8_P87_T0.110220.813
57_L79_L0.110140.812
101_R105_R0.109430.807
45_Q50_L0.109330.806
18_V23_G0.108920.803
19_G27_T0.108610.801
32_I56_S0.108610.801
48_R52_R0.108050.797
34_T88_D0.107360.792
17_L20_S0.107030.789
52_R66_E0.106870.788
43_R68_L0.106050.782
7_Y82_I0.105410.777
30_L91_G0.105250.776
15_L72_L0.105210.776
12_I32_I0.105060.775
28_L46_G0.105010.774
40_W44_R0.10460.771
45_Q73_L0.104260.769
12_I16_I0.10410.768
36_V39_I0.103590.764
32_I109_K0.103540.764
19_G31_V0.102980.759
62_M75_V0.102910.759
9_I31_V0.102860.759
65_E108_M0.102820.758
6_L12_I0.102630.757
35_A91_G0.102090.753
71_A74_A0.102070.753
44_R48_R0.101120.746
18_V30_L0.100970.745
21_W111_V0.100680.743
59_Q78_V0.100240.739
33_L108_M0.099870.737
75_V79_L0.099850.736
37_L75_V0.099640.735
60_G68_L0.099330.733
82_I92_L0.099080.731
60_G86_L0.099030.730
91_G94_L0.099020.730
8_P39_I0.098850.729
22_I27_T0.098340.725
5_L35_A0.098260.725
64_G67_L0.097940.722
89_I109_K0.097810.721
46_G49_A0.097780.721
90_L94_L0.097730.721
42_L53_L0.097480.719
33_L101_R0.097330.718
109_K112_Q0.097180.717
35_A81_I0.097170.717
78_V96_L0.096990.715
82_I109_K0.096860.714
73_L100_R0.096840.714
4_F12_I0.095880.707
37_L92_L0.095640.705
19_G32_I0.095570.705
27_T34_T0.095510.704
97_P100_R0.095480.704
37_L108_M0.095250.702
64_G106_L0.095170.702
14_V25_L0.094850.700
13_A19_G0.09460.698
54_Q65_E0.094550.697
53_L111_V0.094310.696
7_Y89_I0.094160.694
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4dx5A124.80.912
3w9iA0.9916130.923
2v50A0.974810.40.925
2ipqX0.68079.90.926
1ciyA0.4798.40.928
2qkgA0.47066.80.931
1ejpA0.08450.935
3eb7A0.46224.50.936
1ji6A0.428640.938
3aqpA0.99163.90.938
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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