GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
FAINT - Domain of unknown function DUF529
Pfam: PF04385 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 78
Sequences: 933
Seq/Len: 11.96
HH_delta: 0.841 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
44_T47_K0.382472.325
55_S58_V0.340762.071
37_K47_K0.316651.925
37_K44_T0.286231.740
6_N10_S0.282521.717
16_N25_Y0.282261.716
19_D23_N0.271961.653
52_E60_Y0.25081.524
9_S12_Y0.24011.459
12_Y35_C0.236121.435
54_Y58_V0.230461.401
54_Y57_K0.217761.324
29_P53_E0.21691.318
14_V25_Y0.216431.316
7_Q12_Y0.21551.310
5_N40_Y0.21481.306
56_K59_I0.213891.300
40_Y43_K0.212071.289
48_S54_Y0.208461.267
12_Y15_Y0.203571.237
61_Y65_G0.198261.205
57_K60_Y0.194671.183
9_S35_C0.191551.164
16_N23_N0.190481.158
59_I62_S0.189231.150
40_Y45_I0.188451.145
7_Q35_C0.184291.120
58_V61_Y0.182091.107
18_F45_I0.18061.098
55_S61_Y0.175951.070
36_T66_K0.175571.067
3_D49_K0.173791.056
59_I63_K0.16851.024
45_I48_S0.16471.001
29_P33_Y0.163840.996
57_K64_N0.160090.973
10_S14_V0.15940.969
52_E65_G0.159350.969
6_N49_K0.157910.960
54_Y59_I0.156320.950
3_D39_K0.156250.950
39_K45_I0.156160.949
36_T39_K0.154130.937
9_S30_K0.153170.931
43_K66_K0.151780.923
19_D22_V0.14680.892
15_Y24_Y0.146770.892
57_K61_Y0.14650.890
18_F21_G0.146250.889
8_D11_E0.145910.887
2_L7_Q0.144750.880
4_L45_I0.144310.877
36_T50_S0.143890.875
27_Y30_K0.141310.859
4_L40_Y0.139170.846
6_N14_V0.137960.839
14_V28_T0.137930.838
39_K43_K0.136950.832
8_D25_Y0.136310.829
27_Y49_K0.136280.828
2_L30_K0.134020.815
13_N16_N0.133810.813
18_F36_T0.133010.808
44_T49_K0.132670.806
8_D42_D0.13030.792
45_I55_S0.129930.790
50_S53_E0.127770.777
44_T65_G0.127760.777
25_Y40_Y0.127670.776
13_N25_Y0.127170.773
30_K64_N0.126820.771
3_D6_N0.126560.769
20_D23_N0.125050.760
16_N28_T0.125040.760
57_K62_S0.124990.760
52_E55_S0.124650.758
33_Y49_K0.123690.752
7_Q33_Y0.123440.750
34_K38_V0.123410.750
5_N31_P0.122470.744
14_V40_Y0.121710.740
15_Y31_P0.121390.738
51_D54_Y0.120520.733
39_K63_K0.120230.731
17_Y35_C0.120120.730
23_N38_V0.119120.724
34_K44_T0.118790.722
7_Q10_S0.118640.721
26_I57_K0.117970.717
11_E33_Y0.11750.714
54_Y62_S0.116540.708
7_Q36_T0.115970.705
32_G37_K0.115450.702
18_F27_Y0.115360.701
34_K53_E0.11520.700
25_Y28_T0.113690.691
58_V62_S0.113570.690
5_N63_K0.113130.688
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1gqpA0.948721.60.841
4kf9A0.628212.50.856
3ic8A0.487211.50.859
1jhjA0.96158.80.865
4aezA0.91037.20.87
1a31A0.67954.90.879
2b9sA0.67954.40.881
1k7hA0.53.90.884
2e4mC0.71793.70.886
3dwlC13.50.887
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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