GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
PqiA - Paraquat-inducible protein A
Pfam: PF04403 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 160
Sequences: 977
Seq/Len: 6.11
HH_delta: 0.95 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
46_W54_A0.311433.018
26_S35_E0.183351.777
71_S91_L0.180751.751
36_A40_S0.167281.621
3_Q7_A0.162331.573
106_V130_F0.162061.570
45_L57_V0.155631.508
1_S5_P0.155481.507
24_F129_G0.154721.499
11_A15_L0.153951.492
8_L139_L0.152931.482
118_L127_G0.152141.474
59_L64_F0.150651.460
16_F66_L0.150211.455
150_R154_D0.148471.439
11_A139_L0.148341.437
71_S95_L0.148321.437
19_A132_A0.147291.427
1_S151_W0.146711.422
15_L139_L0.144251.398
79_P152_L0.142681.383
70_L73_L0.142151.377
20_N37_S0.141261.369
58_F63_V0.139011.347
148_D153_W0.138981.347
45_L112_L0.135051.309
16_F136_L0.134611.304
17_I21_F0.131391.273
42_I54_A0.130591.265
13_L69_L0.130371.263
93_R113_V0.130131.261
68_K99_G0.129761.257
61_S68_K0.127261.233
62_V109_V0.126881.229
27_L50_Y0.126111.222
61_S105_D0.124551.207
22_F128_P0.123721.199
82_R86_R0.123171.193
127_G132_A0.122191.184
79_P147_F0.121371.176
18_P22_F0.119511.158
74_Y91_L0.119471.158
26_S113_V0.119391.157
41_G140_S0.118491.148
105_D137_V0.116451.128
5_P143_A0.11541.118
115_L124_V0.115281.117
16_F25_L0.114361.108
7_A11_A0.114081.105
83_R138_L0.112651.092
53_L76_L0.112151.087
24_F64_F0.110791.074
75_L103_M0.110371.069
9_A69_L0.109721.063
10_L135_A0.109631.062
112_L118_L0.109221.058
77_F81_R0.109041.057
95_L113_V0.108861.055
128_P139_L0.108291.049
56_L60_F0.108131.048
22_F26_S0.107951.046
25_L37_S0.107621.043
5_P151_W0.107481.041
72_L120_G0.10651.032
24_F53_L0.106451.031
6_L76_L0.106111.028
86_R90_R0.105971.027
102_S133_F0.105521.022
13_L70_L0.104891.016
20_N62_V0.104791.015
106_V109_V0.104511.013
38_L102_S0.10441.012
47_E53_L0.103961.007
112_L127_G0.103731.005
133_F137_V0.103571.004
11_A37_S0.103391.002
55_V59_L0.103221.000
102_S105_D0.103191.000
75_L152_L0.103130.999
85_P89_R0.103080.999
39_L62_V0.103070.999
46_W98_L0.102970.998
27_L117_K0.10230.991
57_V122_A0.102170.990
38_L136_L0.102150.990
105_D136_L0.102140.990
11_A14_I0.102080.989
22_F129_G0.101590.984
8_L146_S0.101340.982
27_L105_D0.101070.979
120_G132_A0.101020.979
14_I55_V0.100650.975
15_L132_A0.100590.975
38_L61_S0.100580.975
74_Y122_A0.100480.974
68_K105_D0.10030.972
26_S33_T0.100110.970
24_F114_A0.099970.969
148_D154_D0.099360.963
131_Y135_A0.099280.962
25_L79_P0.099240.962
67_L117_K0.099230.962
124_V127_G0.09910.960
129_G140_S0.098910.958
12_A69_L0.098760.957
16_F44_A0.098660.956
58_F61_S0.098640.956
112_L124_V0.098630.956
52_F138_L0.098530.955
82_R85_P0.098050.950
31_G123_D0.097740.947
64_F89_R0.097310.943
47_E81_R0.097040.940
51_Y54_A0.097020.940
2_L155_R0.096990.940
41_G104_L0.096380.934
81_R85_P0.096340.934
46_W51_Y0.096150.932
10_L63_V0.095990.930
44_A48_E0.095980.930
10_L90_R0.095980.930
87_G155_R0.095610.926
99_G105_D0.095540.926
62_V87_G0.095040.921
59_L123_D0.094850.919
67_L94_W0.094590.917
22_F132_A0.094290.914
109_V145_S0.094090.912
106_V118_L0.093950.910
107_F110_G0.093460.906
108_V141_M0.093410.905
40_S129_G0.093260.904
126_P131_Y0.093140.902
19_A23_P0.093130.902
111_I121_L0.093070.902
136_L140_S0.092890.900
71_S123_D0.092890.900
53_L60_F0.092860.900
56_L95_L0.092470.896
99_G102_S0.092410.895
41_G130_F0.092250.894
31_G117_K0.09180.890
64_F137_V0.091790.889
44_A57_V0.091640.888
105_D140_S0.091430.886
117_K122_A0.091420.886
126_P130_F0.091330.885
81_R90_R0.090930.881
150_R153_W0.090710.879
75_L108_V0.090440.876
23_P139_L0.08990.871
2_L80_R0.089770.870
92_L143_A0.089350.866
69_L136_L0.089120.864
113_V117_K0.089020.863
67_L155_R0.088940.862
27_L46_W0.08880.860
43_W51_Y0.088720.860
116_V133_F0.088710.860
3_Q73_L0.088340.856
17_I42_I0.088180.854
135_A139_L0.08810.854
42_I58_F0.088090.854
60_F102_S0.088060.853
102_S108_V0.088040.853
104_L111_I0.088040.853
58_F62_V0.088010.853
63_V100_K0.087590.849
98_L105_D0.087590.849
38_L140_S0.087550.848
86_R89_R0.087540.848
41_G57_V0.08740.847
45_L50_Y0.087140.844
25_L30_L0.086960.843
4_R10_L0.086590.839
100_K110_G0.086360.837
6_L80_R0.086280.836
111_I119_S0.086220.835
68_K102_S0.086170.835
10_L84_P0.0860.833
112_L122_A0.085960.833
94_W114_A0.085860.832
74_Y77_F0.085650.830
36_A57_V0.085490.828
29_L121_L0.085120.825
2_L151_W0.08510.825
21_F143_A0.085060.824
35_E127_G0.084970.823
103_M116_V0.084880.822
100_K132_A0.084710.821
87_G90_R0.084310.817
113_V132_A0.084280.817
141_M145_S0.084140.815
70_L86_R0.084110.815
43_W70_L0.08350.809
81_R84_P0.083330.807
99_G124_V0.083330.807
69_L112_L0.083310.807
75_L148_D0.083280.807
85_P88_R0.08320.806
117_K130_F0.083080.805
46_W69_L0.082890.803
4_R146_S0.082850.803
84_P87_G0.082820.803
115_L134_A0.082710.801
3_Q46_W0.082590.800
8_L106_V0.082370.798
12_A136_L0.082310.798
139_L153_W0.082310.798
60_F104_L0.082160.796
151_W154_D0.08210.796
13_L114_A0.081950.794
15_L34_Q0.081910.794
63_V89_R0.081850.793
95_L104_L0.081810.793
66_L128_P0.081810.793
107_F137_V0.081780.792
143_A147_F0.081740.792
68_K140_S0.081310.788
41_G131_Y0.08130.788
79_P86_R0.081260.787
16_F30_L0.081110.786
15_L135_A0.080960.784
16_F148_D0.080880.784
53_L131_Y0.080810.783
107_F113_V0.08080.783
68_K133_F0.080740.782
9_A68_K0.080680.782
62_V94_W0.080560.781
24_F31_G0.080530.780
30_L35_E0.080490.780
70_L84_P0.080340.778
6_L77_F0.08030.778
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2kygC0.154.70.95
3zuxA0.45622.80.955
3d31C0.51252.80.955
3arcM0.2252.40.956
2rddB0.2252.10.957
1btqA0.16251.90.959
2iubA0.40621.60.96
2k1aA0.26251.60.96
1bzkA0.19381.50.961
2onkC0.51881.50.961
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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