GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Dispanin - Interferon-induced transmembrane protein
Pfam: PF04505 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 82
Sequences: 483
Seq/Len: 5.89
HH_delta: 0.892 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
52_D55_G0.668363.785
15_P48_Y0.350091.983
44_V60_S0.345871.959
68_I72_I0.316891.795
58_R62_K0.298071.688
40_Y43_K0.293941.665
65_K69_I0.292431.656
19_L23_I0.282111.598
47_R55_G0.267381.514
35_I39_V0.26271.488
21_L71_I0.257761.460
62_K66_W0.247121.399
54_E57_R0.24691.398
75_I79_I0.242471.373
20_V24_F0.242081.371
17_D45_R0.241111.365
43_K47_R0.238761.352
42_S45_R0.229691.301
33_L66_W0.225351.276
18_Y60_S0.216761.228
25_S67_S0.210861.194
35_I38_I0.207221.173
40_Y62_K0.205591.164
37_A67_S0.20381.154
24_F67_S0.196631.114
47_R52_D0.192531.090
22_S67_S0.191981.087
36_V39_V0.191841.086
48_Y53_Y0.187521.062
30_C39_V0.182251.032
26_T34_G0.181891.030
27_L34_G0.178551.011
36_V40_Y0.177451.005
22_S41_S0.176190.998
57_R61_R0.170480.965
17_D41_S0.166890.945
21_L67_S0.165940.940
22_S25_S0.165830.939
35_I64_K0.165160.935
52_D56_A0.162680.921
54_E58_R0.161780.916
44_V59_A0.161680.916
21_L25_S0.158930.900
26_T29_C0.158810.899
56_A60_S0.158580.898
25_S74_G0.15830.896
69_I78_I0.156720.888
19_L38_I0.155960.883
21_L24_F0.155830.882
25_S71_I0.153550.870
44_V48_Y0.153380.869
72_I76_V0.153170.867
53_Y57_R0.151860.860
63_A68_I0.151530.858
70_A74_G0.151240.856
15_P53_Y0.147030.833
41_S49_A0.145860.826
21_L41_S0.14530.823
16_P60_S0.144580.819
29_C74_G0.142060.804
19_L39_V0.141910.804
33_L70_A0.139720.791
22_S37_A0.139380.789
23_I30_C0.139080.788
26_T31_W0.138430.784
26_T38_I0.137440.778
28_C74_G0.136790.775
62_K76_V0.135750.769
69_I73_I0.135450.767
76_V80_L0.135290.766
18_Y47_R0.134350.761
74_G78_I0.133780.758
73_I76_V0.133130.754
36_V66_W0.132240.749
50_A54_E0.129040.731
51_G74_G0.128980.730
71_I74_G0.128890.730
64_K70_A0.127930.724
18_Y56_A0.127360.721
23_I38_I0.126870.718
34_G47_R0.125330.710
25_S79_I0.125160.709
49_A54_E0.12390.702
53_Y79_I0.123290.698
44_V66_W0.123140.697
25_S33_L0.121840.690
31_W56_A0.121730.689
46_S50_A0.121240.687
62_K73_I0.121220.686
62_K65_K0.120980.685
37_A46_S0.120370.682
18_Y21_L0.12010.680
21_L48_Y0.120070.680
14_P23_I0.117590.666
44_V56_A0.11690.662
43_K68_I0.116580.660
43_K46_S0.116390.659
43_K75_I0.115530.654
73_I78_I0.115380.653
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4ea3A0.987815.90.892
3ayfA0.93913.90.895
3sn6R0.963412.50.897
3tlwA112.30.897
4febA0.341511.70.898
1rz2A0.3537110.899
1v54C0.85379.50.902
1m56C0.85379.50.902
1qleC0.86599.30.902
3oduA0.98788.10.905
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

Page generated in 0.0126 seconds.