GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF594 - Protein of unknown function DUF594
Pfam: PF04578 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 59
Sequences: 440
Seq/Len: 7.46
HH_delta: 0.902 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
39_Q42_S0.375722.371
19_V57_A0.278381.757
13_W58_G0.260041.641
40_L46_F0.253711.601
12_R15_V0.243711.538
22_E25_C0.238571.506
19_V22_E0.237811.501
45_E53_L0.232561.468
35_S41_S0.225321.422
34_E39_Q0.212271.340
31_C37_A0.206091.301
31_C50_V0.202721.279
34_E37_A0.199891.262
17_A29_P0.195731.235
19_V23_M0.193571.222
24_L37_A0.18641.176
28_A47_I0.18041.139
46_F50_V0.179891.135
14_K42_S0.174041.098
24_L38_K0.170451.076
32_S35_S0.169591.070
19_V31_C0.16681.053
11_D44_G0.16631.050
51_W59_I0.163871.034
17_A33_A0.162661.027
53_L56_H0.160341.012
49_H54_L0.157770.996
15_V19_V0.157190.992
11_D37_A0.156110.985
27_A35_S0.149630.944
16_L32_S0.149410.943
16_L34_E0.148670.938
35_S49_H0.148140.935
47_I55_T0.14790.933
45_E51_W0.147640.932
29_P33_A0.144230.910
19_V25_C0.143140.903
34_E53_L0.143080.903
14_K41_S0.142830.901
21_V28_A0.142440.899
15_V47_I0.141890.896
14_K18_D0.140430.886
30_S48_T0.140170.885
48_T56_H0.138930.877
47_I52_L0.138020.871
25_C57_A0.137780.870
29_P55_T0.137390.867
12_R49_H0.136040.859
8_D11_D0.135290.854
28_A55_T0.134960.852
17_A32_S0.134890.851
24_L40_L0.134480.849
28_A52_L0.132150.834
18_D56_H0.131870.832
34_E38_K0.131750.832
8_D17_A0.130630.824
30_S51_W0.129660.818
23_M26_Y0.129470.817
31_C35_S0.129190.815
51_W54_L0.127410.804
31_C38_K0.126960.801
24_L42_S0.126890.801
24_L34_E0.125380.791
38_K42_S0.123210.778
37_A40_L0.12220.771
18_D28_A0.122060.770
38_K41_S0.121540.767
29_P32_S0.119850.756
14_K38_K0.11910.752
11_D34_E0.117960.745
27_A30_S0.117490.742
10_E26_Y0.116480.735
15_V22_E0.115970.732
52_L56_H0.115760.731
32_S59_I0.11540.728
32_S54_L0.115110.727
34_E59_I0.114990.726
50_V58_G0.114540.723
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3rf2A0.81367.10.902
3v1vA0.93225.50.907
4b94A0.96614.50.91
4b15A0.830540.913
3vywA0.96613.30.916
4h7yA0.94922.90.917
3dukA0.3392.80.919
1cnvA0.89832.70.919
1uqtA0.62712.40.921
1k1xA0.81362.40.921
If you are interested in a protein containing this domain,
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