GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
PLAC8 - PLAC8 family
Pfam: PF04749 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 106
Sequences: 774
Seq/Len: 7.3
HH_delta: 0.919 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
18_A25_S0.731994.809
89_C93_C0.554373.642
16_C20_F0.442492.907
75_R87_D0.380092.497
91_S102_E0.286451.882
71_R101_Q0.27591.813
75_R82_G0.274441.803
100_C104_R0.269821.773
18_A100_C0.257921.694
88_C92_C0.25481.674
29_N102_E0.244751.608
5_L90_C0.241611.587
11_D104_R0.238211.565
98_A102_E0.236021.551
74_I102_E0.221341.454
91_S98_A0.220751.450
90_C98_A0.215851.418
73_Q77_R0.214761.411
29_N106_L0.21361.403
48_C51_F0.212161.394
82_G87_D0.210741.385
3_T104_R0.199241.309
5_L94_C0.196181.289
4_G19_C0.193761.273
51_F54_F0.193031.268
14_S17_L0.19291.267
17_L25_S0.190111.249
11_D15_C0.181241.191
17_L28_Q0.179621.180
10_S14_S0.174811.148
74_I106_L0.171391.126
83_S86_E0.168471.107
9_F12_P0.167711.102
14_S103_A0.166721.095
8_C15_C0.161841.063
27_G31_E0.161571.061
67_G102_E0.161291.060
30_A34_G0.157991.038
36_G106_L0.157011.032
87_D94_C0.15651.028
98_A101_Q0.155151.019
21_C65_C0.152811.004
48_C81_Q0.151320.994
16_C19_C0.148630.976
49_L67_G0.147190.967
80_I83_S0.14680.964
23_C26_F0.146790.964
13_G95_P0.146750.964
29_N103_A0.146190.960
48_C55_G0.146150.960
94_C97_C0.143350.942
26_F102_E0.141380.929
17_L24_C0.140720.925
48_C52_C0.139350.916
26_F70_L0.135560.891
21_C24_C0.133430.877
67_G91_S0.132490.870
29_N32_R0.130490.857
67_G95_P0.12970.852
81_Q105_E0.128680.845
50_C54_F0.128110.842
31_E103_A0.128070.841
49_L53_C0.127550.838
1_W75_R0.127480.838
80_I84_C0.126480.831
24_C28_Q0.126160.829
15_C85_C0.125930.827
25_S33_L0.125780.826
73_Q98_A0.124990.821
54_F106_L0.124820.820
16_C21_C0.12410.815
6_C12_P0.124080.815
35_D79_G0.123680.813
74_I105_E0.121870.801
6_C15_C0.121790.800
34_G70_L0.121670.799
14_S28_Q0.12090.794
3_T74_I0.120660.793
86_E92_C0.120280.790
17_L20_F0.119760.787
55_G83_S0.118310.777
85_C89_C0.118210.777
65_C72_Q0.117890.775
37_P50_C0.117660.773
7_D74_I0.117340.771
35_D105_E0.11720.770
73_Q106_L0.116830.768
28_Q32_R0.115940.762
85_C88_C0.115860.761
52_C77_R0.114880.755
14_S25_S0.114310.751
3_T105_E0.11380.748
49_L55_G0.113640.747
32_R103_A0.113520.746
35_D77_R0.113450.745
45_G51_F0.112980.742
33_L102_E0.112690.740
91_S97_C0.112630.740
63_G96_P0.111840.735
8_C11_D0.111280.731
72_Q86_E0.109980.723
5_L63_G0.109150.717
12_P93_C0.108320.712
70_L84_C0.108090.710
49_L52_C0.107890.709
69_S83_S0.107670.707
102_E105_E0.107650.707
86_E96_P0.107130.704
1_W70_L0.107050.703
3_T10_S0.106920.702
63_G66_Y0.106860.702
10_S65_C0.106790.702
19_C96_P0.106710.701
24_C77_R0.106690.701
25_S29_N0.106540.700
21_C64_W0.10640.699
67_G98_A0.106030.697
2_S76_E0.105690.694
75_R94_C0.104440.686
72_Q84_C0.104310.685
71_R102_E0.104270.685
1_W99_L0.103850.682
26_F30_A0.102940.676
48_C53_C0.102820.676
96_P106_L0.102730.675
26_F99_L0.102570.674
50_C99_L0.102430.673
97_C101_Q0.102040.670
6_C89_C0.101240.665
71_R74_I0.100060.657
1_W72_Q0.099850.656
11_D47_C0.099380.653
6_C16_C0.099230.652
99_L102_E0.099190.652
34_G45_G0.098980.650
5_L96_P0.098980.650
7_D80_I0.098410.647
47_C70_L0.097960.644
22_P99_L0.097820.643
4_G7_D0.09780.643
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2ywmA0.40577.40.919
3f9kA0.471730.932
1a8lA0.40572.50.935
4g6dA0.38682.20.937
1kilE0.42452.20.937
3kp9A0.94342.20.937
3hphA0.462320.938
1k6yA0.46231.70.94
4fw2A0.4341.30.944
3iv4A0.35851.10.946
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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