GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
VanZ - VanZ like family
Pfam: PF04892 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 133
Sequences: 622
Seq/Len: 4.68
HH_delta: 0.925 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
85_G116_A0.605625.120
37_P110_L0.289832.450
86_F113_T0.277382.345
90_L109_V0.270782.289
64_L88_F0.232081.962
97_L104_F0.217931.842
56_G111_A0.216771.833
78_W117_L0.203091.717
34_N105_D0.194631.645
13_V92_I0.194261.642
89_S113_T0.190171.608
57_H112_N0.183111.548
58_I118_L0.180831.529
57_H63_P0.180791.528
89_S112_N0.175431.483
53_D111_A0.167861.419
99_L102_R0.165251.397
16_Y102_R0.164881.394
91_F95_I0.163451.382
13_V16_Y0.161731.367
93_E96_Q0.159951.352
89_S99_L0.149771.266
63_P112_N0.149721.266
61_F102_R0.149611.265
65_G119_G0.148911.259
98_F102_R0.147921.251
38_F107_D0.146721.240
18_S101_G0.145941.234
60_L92_I0.144951.225
14_L95_I0.143371.212
14_L18_S0.141441.196
88_F92_I0.13971.181
53_D101_G0.138421.170
60_L102_R0.136821.157
37_P106_I0.135591.146
57_H119_G0.133081.125
34_N37_P0.13241.119
58_I111_A0.131491.112
86_F90_L0.130191.101
48_N64_L0.130151.100
34_N38_F0.129691.096
86_F104_F0.129681.096
34_N107_D0.127871.081
10_V14_L0.125791.063
79_L121_L0.125071.057
40_S43_F0.12451.053
53_D56_G0.124371.051
74_R81_A0.123281.042
53_D102_R0.123181.041
82_I113_T0.122481.035
104_F109_V0.121921.031
106_I110_L0.121441.027
51_F59_L0.12121.025
34_N106_I0.120821.021
51_F55_I0.120671.020
9_L88_F0.118751.004
107_D112_N0.118130.999
88_F95_I0.117920.997
85_G89_S0.117460.993
106_I109_V0.116190.982
69_P120_Y0.115330.975
68_L116_A0.115050.973
70_L127_R0.114490.968
58_I125_L0.113330.958
93_E108_D0.11260.952
10_V15_F0.112560.952
63_P105_D0.112030.947
8_L12_I0.111830.945
82_I117_L0.109130.923
83_L87_L0.109110.922
16_Y60_L0.108890.921
49_N54_K0.108850.920
64_L85_G0.107530.909
54_K57_H0.107110.906
121_L125_L0.107070.905
59_L83_L0.105730.894
86_F109_V0.105580.893
10_V67_L0.105540.892
37_P105_D0.105340.891
9_L60_L0.105040.888
53_D57_H0.104970.887
9_L61_F0.10410.880
57_H89_S0.104020.879
45_F50_A0.103120.872
66_F124_R0.102810.869
29_S32_S0.102410.866
34_N111_A0.102370.865
64_L125_L0.102060.863
16_Y101_G0.102040.863
73_R128_K0.101490.858
58_I62_F0.101070.854
16_Y97_L0.100930.853
12_I19_L0.100680.851
117_L128_K0.100110.846
67_L71_L0.099730.843
41_I111_A0.099350.840
65_G107_D0.099250.839
9_L99_L0.099020.837
33_L104_F0.09890.836
62_F118_L0.098630.834
71_L84_I0.097880.828
97_L119_G0.097530.825
123_Y127_R0.097430.824
62_F119_G0.097320.823
16_Y105_D0.097240.822
66_F117_L0.096750.818
53_D107_D0.096520.816
41_I107_D0.096230.814
78_W120_Y0.096090.812
15_F55_I0.095970.811
87_L90_L0.094670.800
28_S59_L0.094090.795
16_Y107_D0.093380.789
89_S116_A0.092720.784
63_P107_D0.092380.781
42_R121_L0.092020.778
65_G112_N0.092010.778
39_S114_L0.091970.778
58_I114_L0.09170.775
90_L114_L0.091660.775
86_F91_F0.091630.775
98_F101_G0.091610.774
63_P119_G0.091540.774
89_S109_V0.091430.773
11_F16_Y0.09090.768
47_S128_K0.090290.763
64_L84_I0.090120.762
92_I112_N0.08990.760
80_L126_I0.089720.759
79_L83_L0.089720.759
109_V114_L0.089220.754
73_R113_T0.088790.751
102_R119_G0.088580.749
57_H93_E0.088440.748
53_D61_F0.08830.747
65_G69_P0.088250.746
89_S104_F0.088170.745
52_I59_L0.08770.741
84_I91_F0.087590.741
108_D119_G0.087570.740
66_F113_T0.087130.737
57_H108_D0.086570.732
54_K111_A0.086330.730
11_F18_S0.086120.728
81_A109_V0.085580.724
36_I106_I0.085460.723
18_S60_L0.08540.722
43_F46_L0.085320.721
52_I101_G0.084890.718
94_L98_F0.084640.716
46_L49_N0.084230.712
14_L92_I0.083960.710
31_P100_P0.083840.709
58_I119_G0.083340.705
110_L114_L0.081450.689
44_F111_A0.081420.688
53_D99_L0.081330.688
56_G92_I0.081310.687
81_A89_S0.081230.687
42_R79_L0.080990.685
18_S67_L0.080950.684
44_F55_I0.080550.681
57_H62_F0.080260.679
51_F122_L0.080250.678
77_S110_L0.08020.678
77_S98_F0.080020.677
82_I95_I0.079780.674
13_V60_L0.079770.674
74_R80_L0.079660.673
94_L104_F0.079510.672
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4httA0.80458.70.925
4b4aA0.83464.10.935
4b19A0.20330.939
4gc0A0.56392.90.939
1zzaA0.24062.70.94
2yevB0.43612.60.94
2nr9A0.90232.50.941
3j1zP0.49622.40.942
1fftB0.48122.10.943
2kv5A0.210520.944
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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