GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
Wzy_C - O-Antigen ligase
Pfam: PF04932 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0499
Length: 163
Sequences: 3161
Seq/Len: 19.39
HH_delta: 0.919 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
110_H115_Y0.888874.107
107_F151_L0.884764.088
115_Y119_N0.799823.696
154_T158_G0.701763.243
149_Q153_E0.629862.910
100_W148_L0.544552.516
151_L159_L0.490282.265
150_I162_F0.480312.219
103_A148_L0.479472.216
145_N148_L0.479052.214
103_A143_P0.475822.199
75_F78_S0.473032.186
143_P149_Q0.427151.974
104_L108_K0.407991.885
115_Y152_V0.368241.702
107_F111_P0.360051.664
14_G19_W0.345451.596
103_A107_F0.34021.572
15_S18_A0.333891.543
99_I144_H0.333551.541
117_Y154_T0.33221.535
157_I161_L0.324971.502
157_I160_A0.31811.470
105_E108_K0.315831.459
110_H113_F0.312361.443
97_L101_K0.301461.393
94_G97_L0.299671.385
106_M115_Y0.299271.383
106_M152_V0.298341.379
101_K105_E0.297371.374
143_P146_Q0.294551.361
150_I154_T0.290321.342
107_F156_I0.287861.330
37_R40_R0.287061.326
106_M109_E0.283831.312
103_A152_V0.282041.303
108_K111_P0.280351.295
142_H149_Q0.2791.289
107_F159_L0.267041.234
96_R144_H0.267011.234
99_I143_P0.266571.232
10_I13_S0.263941.220
109_E115_Y0.263081.216
116_G153_E0.259841.201
150_I159_L0.259441.199
143_P152_V0.25511.179
144_H149_Q0.24851.148
47_I54_L0.246771.140
75_F79_I0.245191.133
6_S9_A0.244681.131
100_W145_N0.242881.122
146_Q150_I0.242581.121
156_I160_A0.242511.121
95_G99_I0.236571.093
33_F37_R0.232481.074
98_F101_K0.231371.069
34_Y37_R0.228511.056
21_A25_A0.223521.033
146_Q149_Q0.222921.030
147_Y151_L0.221431.023
113_F157_I0.214830.993
10_I22_L0.2120.980
28_L32_L0.210870.974
17_G21_A0.207860.960
43_L46_I0.204840.947
77_E80_F0.204770.946
102_S106_M0.202820.937
4_I8_L0.199780.923
147_Y159_L0.198040.915
112_I156_I0.198030.915
107_F152_V0.197980.915
26_L30_L0.197690.913
31_L35_R0.196780.909
106_M120_F0.195610.904
103_A120_F0.193640.895
107_F147_Y0.192450.889
40_R43_L0.190560.881
154_T157_I0.187070.864
15_S96_R0.184990.855
107_F157_I0.183780.849
118_G153_E0.1830.846
100_W144_H0.182110.841
7_L22_L0.181540.839
42_L45_L0.181180.837
24_I46_I0.17930.829
14_G144_H0.177860.822
9_A17_G0.17560.811
142_H145_N0.173440.801
103_A144_H0.173260.801
131_Y134_N0.173150.800
15_S19_W0.172920.799
15_S143_P0.172370.796
80_F84_G0.171260.791
102_S105_E0.171180.791
16_R151_L0.171130.791
104_L107_F0.170780.789
22_L26_L0.168060.777
95_G98_F0.167760.775
21_A28_L0.165830.766
17_G20_I0.165620.765
120_F152_V0.165550.765
140_Y143_P0.164460.760
49_I52_S0.16390.757
37_R74_N0.16320.754
33_F42_L0.162930.753
83_S86_N0.162620.751
32_L36_K0.161980.748
34_Y41_V0.15990.739
20_I23_L0.159240.736
26_L50_A0.158780.734
79_I145_N0.158680.733
10_I18_A0.158330.732
9_A82_G0.158290.731
115_Y153_E0.158290.731
97_L100_W0.15770.729
34_Y38_R0.154140.712
17_G97_L0.153630.710
151_L158_G0.153410.709
38_R44_K0.153320.708
142_H153_E0.151990.702
41_V45_L0.150910.697
149_Q152_V0.150180.694
100_W142_H0.148550.686
103_A106_M0.148360.686
50_A105_E0.147650.682
120_F153_E0.14750.682
5_L94_G0.14650.677
151_L154_T0.146190.676
47_I51_L0.145060.670
94_G98_F0.144810.669
39_K47_I0.143930.665
35_R81_S0.143140.661
112_I158_G0.143050.661
11_F86_N0.142730.660
10_I120_F0.142410.658
147_Y162_F0.141990.656
107_F115_Y0.141470.654
78_S82_G0.14140.653
43_L48_V0.140970.651
52_S56_L0.140890.651
108_K156_I0.140810.651
120_F143_P0.140790.651
112_I115_Y0.14060.650
33_F40_R0.139620.645
120_F141_D0.13940.644
78_S87_S0.139050.643
106_M110_H0.138440.640
15_S120_F0.138380.639
84_G159_L0.138240.639
111_P151_L0.138140.638
53_L78_S0.138110.638
75_F94_G0.137110.634
21_A142_H0.13710.634
39_K43_L0.136720.632
28_L33_F0.13610.629
17_G134_N0.135980.628
118_G154_T0.13590.628
103_A151_L0.13550.626
43_L47_I0.135240.625
99_I146_Q0.135060.624
16_R21_A0.133960.619
30_L105_E0.132520.612
18_A140_Y0.132180.611
17_G115_Y0.131760.609
40_R57_L0.131760.609
151_L157_I0.13120.606
48_V83_S0.130960.605
17_G140_Y0.130840.605
51_L54_L0.130650.604
100_W143_P0.130290.602
38_R54_L0.130160.601
30_L38_R0.130130.601
25_A104_L0.129930.600
118_G150_I0.129920.600
51_L87_S0.129810.600
105_E109_E0.129230.597
32_L111_P0.128940.596
27_I34_Y0.128910.596
102_S152_V0.128870.595
86_N143_P0.128710.595
38_R41_V0.128480.594
30_L77_E0.128390.593
29_F139_H0.128090.592
114_G155_G0.127230.588
99_I120_F0.127210.588
76_I80_F0.12720.588
44_K55_F0.126520.585
4_I57_L0.126330.584
14_G100_W0.126120.583
80_F87_S0.12610.583
35_R43_L0.125910.582
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3dh4A0.80984.10.919
2jwaA0.21472.80.925
4humA0.49082.40.927
3rceA0.95712.20.928
2kluA0.14722.10.929
2a65A0.93251.80.932
1afoA0.1841.80.932
2ks1B0.19021.70.933
2losA0.41721.40.935
2rddB0.2271.40.935
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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