GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
BTP - Bacterial Transmembrane Pair family
Pfam: PF05232 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 67
Sequences: 621
Seq/Len: 9.27
HH_delta: 0.897 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
45_L49_V0.485722.602
5_R8_L0.401662.151
26_A33_L0.393582.108
3_F52_Y0.312811.675
59_D62_E0.282311.512
5_R58_F0.281661.509
52_Y56_W0.276571.481
18_L44_S0.267581.433
26_A29_L0.266431.427
3_F7_I0.25451.363
44_S48_M0.253121.356
17_A43_L0.251961.350
57_L61_I0.249231.335
13_F59_D0.245711.316
21_S43_L0.240041.286
47_A51_N0.239071.281
27_W33_L0.23711.270
5_R51_N0.224351.202
49_V53_I0.22311.195
31_I36_A0.220931.183
1_R59_D0.21731.164
7_I60_K0.215691.155
7_I52_Y0.21141.132
53_I56_W0.210041.125
1_R5_R0.204511.095
1_R47_A0.199431.068
24_L27_W0.199391.068
18_L41_V0.197961.060
41_V44_S0.197411.057
49_V52_Y0.194141.040
19_L25_I0.193431.036
16_G20_I0.19271.032
23_P27_W0.192151.029
9_H22_V0.1911.023
25_I36_A0.190071.018
10_A51_N0.188021.007
23_P26_A0.184370.988
32_S35_Q0.184180.987
30_G35_Q0.182660.978
44_S47_A0.180740.968
25_I49_V0.180660.968
5_R59_D0.180530.967
10_A52_Y0.179830.963
40_D44_S0.178140.954
14_E48_M0.176930.948
6_R59_D0.176360.945
15_V42_G0.175820.942
2_S59_D0.17490.937
30_G57_L0.174360.934
22_V47_A0.172610.925
17_A50_W0.17150.919
12_L43_L0.171370.918
10_A48_M0.168290.901
4_K8_L0.166690.893
2_S5_R0.165770.888
26_A30_G0.163290.875
47_A50_W0.158750.850
2_S53_I0.158550.849
28_W31_I0.157140.842
34_W38_A0.155070.831
50_W54_F0.154720.829
8_L19_L0.152550.817
3_F11_I0.151950.814
26_A32_S0.151060.809
21_S44_S0.150970.809
40_D47_A0.149740.802
30_G42_G0.148530.796
4_K30_G0.146040.782
9_H59_D0.145080.777
19_L35_Q0.143360.768
12_L45_L0.142880.765
4_K7_I0.142810.765
21_S25_I0.141030.755
4_K53_I0.139350.746
13_F54_F0.138760.743
11_I15_V0.138580.742
40_D43_L0.138560.742
49_V62_E0.138540.742
1_R43_L0.138150.740
14_E22_V0.137270.735
15_V64_R0.136880.733
15_V34_W0.136340.730
11_I38_A0.136120.729
11_I45_L0.136010.728
38_A41_V0.134730.722
26_A31_I0.132320.709
5_R62_E0.131620.705
15_V19_L0.131210.703
15_V24_L0.130630.700
43_L48_M0.129180.692
27_W40_D0.128650.689
42_G60_K0.126870.680
17_A36_A0.12610.675
18_L55_N0.125740.673
9_H62_E0.125470.672
6_R9_H0.124710.668
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2cfqA17.10.897
3j09A0.98516.50.899
4apsA15.90.901
3j08A0.95525.60.901
2xutA150.904
4b03D0.68664.30.906
1vf5B0.59740.907
3b8cA0.91043.90.908
4j05A13.60.909
2hpiA0.77613.30.911
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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