GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF748 - Domain of Unknown Function (DUF748)
Pfam: PF05359 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Clan: CL0401
Length: 151
Sequences: 920
Seq/Len: 6.09
HH_delta: 0.909 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
19_D92_Y0.250472.606
78_T111_N0.234282.437
12_N34_N0.191341.991
7_H38_D0.170071.769
129_L132_L0.166131.728
81_L84_L0.166111.728
34_N53_S0.163711.703
110_L123_A0.161671.682
107_D130_N0.151411.575
80_K109_D0.148891.549
51_S65_S0.147691.537
64_A77_G0.146911.528
65_S78_T0.145951.518
11_K34_N0.144081.499
63_S80_K0.143171.489
21_S30_L0.138681.443
54_A62_L0.134511.399
2_R5_I0.134341.398
38_D49_P0.132581.379
32_D55_S0.132381.377
86_L93_L0.130981.363
26_F129_L0.129311.345
51_S63_S0.127211.323
35_L52_L0.126941.321
50_V77_G0.125521.306
7_H36_T0.123571.286
18_T27_K0.123071.280
76_D113_K0.122261.272
10_L31_S0.121431.263
18_T133_R0.119091.239
9_S36_T0.115971.207
90_Q98_P0.115741.204
99_F134_L0.11541.201
56_L62_L0.115371.200
12_N118_D0.113271.178
31_S55_S0.113111.177
99_F125_G0.11231.168
109_D126_K0.110861.153
14_R107_D0.110851.153
30_L96_Y0.110311.148
11_K36_T0.110211.147
83_N124_N0.10961.140
96_Y132_L0.109411.138
81_L108_L0.109371.138
50_V68_L0.109121.135
16_N29_E0.108751.131
77_G112_Y0.108391.128
48_A69_S0.106281.106
17_F92_Y0.104591.088
75_S98_P0.104521.087
83_N105_Q0.102331.065
99_F137_K0.102251.064
90_Q138_G0.101931.060
35_L54_A0.101791.059
19_D26_F0.100111.042
102_Q133_R0.099541.036
14_R29_E0.099021.030
48_A76_D0.09891.029
17_F26_F0.098791.028
39_N68_L0.098481.025
57_N60_G0.097681.016
85_D103_S0.097631.016
34_N106_L0.096831.007
5_I73_L0.096451.003
28_L89_L0.096251.001
33_I68_L0.09621.001
67_K126_K0.095890.998
60_G125_G0.095070.989
62_L81_L0.09490.987
26_F30_L0.094630.985
29_E108_L0.094620.984
125_G135_A0.094060.979
62_L103_S0.093990.978
10_L16_N0.093740.975
13_G32_D0.092580.963
64_A112_Y0.092560.963
85_D105_Q0.092320.960
11_K65_S0.091980.957
111_N124_N0.091930.956
103_S119_G0.091670.954
41_S44_S0.091670.954
97_L127_L0.091430.951
79_L133_R0.091420.951
25_P31_S0.09110.948
36_T53_S0.091070.947
15_I72_P0.09080.945
28_L112_Y0.090750.944
40_L48_A0.090620.943
16_N27_K0.090450.941
112_Y125_G0.090430.941
42_T45_N0.090410.941
85_D137_K0.090270.939
43_D46_E0.089260.929
27_K54_A0.088690.923
19_D91_P0.088630.922
64_A70_P0.087910.915
21_S25_P0.087850.914
26_F79_L0.087850.914
61_T71_F0.08710.906
79_L110_L0.087030.905
93_L99_F0.086570.901
3_I42_T0.086360.898
39_N74_D0.086320.898
64_A87_A0.086180.897
85_D88_P0.086030.895
17_F121_L0.086010.895
68_L124_N0.085320.888
68_L75_S0.085310.888
124_N130_N0.085120.886
72_P119_G0.084850.883
123_A133_R0.084750.882
15_I33_I0.084630.880
22_V79_L0.084040.874
96_Y134_L0.083910.873
56_L84_L0.083720.871
109_D128_S0.083520.869
90_Q104_G0.083480.869
68_L72_P0.083390.868
48_A66_G0.083360.867
90_Q125_G0.083250.866
52_L90_Q0.083170.865
12_N77_G0.083120.865
63_S111_N0.082870.862
48_A70_P0.082860.862
123_A134_L0.082810.862
29_E105_Q0.08270.860
100_Q124_N0.082540.859
57_N66_G0.082510.858
86_L127_L0.08240.857
22_V95_Q0.082370.857
69_S129_L0.082020.853
97_L132_L0.0820.853
34_N107_D0.081680.850
30_L75_S0.081640.849
56_L60_G0.081540.848
17_F66_G0.081530.848
6_D39_N0.081420.847
43_D101_L0.081310.846
90_Q99_F0.081270.846
17_F89_L0.081210.845
47_P67_K0.081050.843
39_N126_K0.080510.838
10_L75_S0.080420.837
99_F135_A0.080380.836
65_S111_N0.080280.835
37_L113_K0.080190.834
35_L105_Q0.080170.834
48_A108_L0.079790.830
49_P52_L0.079630.828
16_N56_L0.079580.828
5_I39_N0.079470.827
53_S129_L0.079330.825
39_N127_L0.079150.823
69_S105_Q0.078960.821
30_L107_D0.078850.820
40_L86_L0.07880.820
74_D132_L0.07870.819
67_K89_L0.078450.816
103_S131_D0.078440.816
9_S12_N0.078130.813
66_G129_L0.078120.813
100_Q134_L0.077950.811
30_L54_A0.077660.808
87_A104_G0.07760.807
6_D46_E0.077590.807
55_S107_D0.077420.805
47_P120_Q0.077310.804
42_T98_P0.077230.803
11_K103_S0.076630.797
7_H33_I0.076420.795
12_N88_P0.076410.795
36_T51_S0.076380.795
78_T112_Y0.076280.794
90_Q123_A0.076230.793
44_S65_S0.076050.791
86_L104_G0.075910.790
103_S135_A0.075870.789
8_L37_L0.075810.789
48_A89_L0.075740.788
46_E61_T0.075710.788
24_P30_L0.075690.787
22_V26_F0.075670.787
15_I61_T0.075450.785
112_Y123_A0.075410.785
62_L119_G0.075410.785
57_N79_L0.075350.784
5_I46_E0.075320.784
98_P135_A0.075320.784
60_G84_L0.075270.783
116_K137_K0.075180.782
110_L125_G0.075010.780
6_D89_L0.074930.780
71_F80_K0.07480.778
49_P65_S0.074720.777
58_G63_S0.074480.775
8_L53_S0.073960.769
27_K74_D0.073710.767
102_Q137_K0.073690.767
26_F112_Y0.073640.766
17_F52_L0.073380.763
14_R82_N0.073340.763
50_V78_T0.073060.760
28_L59_G0.072960.759
88_P110_L0.072920.759
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
3petA0.920511.50.909
1evlA0.337711.10.909
1qf6A0.33779.80.911
3fyfA0.78816.30.918
3h09A0.88744.70.923
3iklA0.3514.30.924
4f4cA0.82124.10.925
4khbD0.801340.925
4jimA0.33773.70.926
1iktA0.63583.70.927
If you are interested in a protein containing this domain,
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