GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
YiaAB - yiaAB two helix domain
Pfam: PF05360 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 53
Sequences: 324
Seq/Len: 6.11
HH_delta: 0.867 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
45_F48_Q0.279251.757
1_F5_S0.270171.700
27_L31_G0.249361.569
24_P43_S0.237581.495
49_K52_R0.234081.473
49_K53_D0.232251.461
28_S33_Y0.224811.414
17_L21_W0.224581.413
7_I15_L0.221631.394
20_L23_A0.218961.378
14_V18_I0.216191.360
25_L41_L0.21111.328
12_S34_A0.208221.310
7_I11_I0.203641.281
11_I14_V0.196431.236
29_E41_L0.194541.224
15_L35_M0.192741.213
37_L40_L0.191931.208
35_M39_F0.175871.106
25_L29_E0.174541.098
35_M38_L0.167611.055
10_G18_I0.164621.036
1_F50_T0.162391.022
12_S16_M0.160991.013
11_I36_G0.160981.013
21_W37_L0.160841.012
26_D43_S0.159651.004
14_V21_W0.159211.002
40_L46_T0.158030.994
39_F42_F0.157770.993
3_G18_I0.156580.985
7_I22_N0.15630.983
9_F12_S0.156170.983
5_S50_T0.153710.967
35_M40_L0.153030.963
23_A37_L0.152130.957
12_S35_M0.152090.957
18_I22_N0.149620.941
8_S12_S0.14810.932
3_G10_G0.14730.927
10_G14_V0.146840.924
5_S38_L0.146330.921
12_S28_S0.145960.918
7_I10_G0.145190.913
31_G48_Q0.143280.901
23_A36_G0.143050.900
12_S17_L0.14150.890
20_L27_L0.139820.880
25_L37_L0.139190.876
14_V36_G0.13820.869
30_K50_T0.137690.866
42_F48_Q0.135280.851
14_V43_S0.13390.842
43_S47_L0.133540.840
4_Q8_S0.131840.829
16_M34_A0.131740.829
8_S25_L0.131460.827
19_G35_M0.131420.827
2_V11_I0.130570.821
9_F45_F0.130230.819
29_E33_Y0.129970.818
27_L30_K0.129450.814
3_G32_Y0.129010.812
21_W26_D0.128970.811
17_L47_L0.127030.799
14_V34_A0.125630.790
33_Y48_Q0.125590.790
40_L50_T0.124270.782
47_L51_V0.123880.779
5_S43_S0.122940.773
10_G34_A0.122330.770
20_L25_L0.121810.766
25_L33_Y0.121280.763
27_L32_Y0.119530.752
4_Q7_I0.119430.751
43_S46_T0.119410.751
1_F25_L0.119030.749
23_A48_Q0.118880.748
13_I44_A0.11820.744
47_L50_T0.117010.736
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
2iubA110.40.867
4ev6A110.10.867
4i0uA15.50.882
3m73A14.20.888
3qbgA0.98113.20.894
4knfA0.96232.70.897
4fbzA0.98112.20.902
2l6xA0.96232.10.903
2i68A0.96231.90.904
4jq6A0.96231.70.907
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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