GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
AzlD - Branched-chain amino acid transport protein (AzlD)
Pfam: PF05437 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 99
Sequences: 1378
Seq/Len: 13.92
HH_delta: 0.888 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
77_V90_A0.7233.877
73_V94_A0.720623.865
74_A91_G0.480442.577
8_M11_V0.397782.133
17_V21_L0.339091.819
76_L80_R0.32451.740
8_M44_L0.313171.680
79_L82_R0.296381.589
41_P45_A0.288181.546
83_N86_L0.286821.538
14_L18_L0.286431.536
75_A79_L0.283541.521
73_V90_A0.278391.493
6_L10_L0.269761.447
92_V96_A0.263661.414
13_Y17_V0.255851.372
74_A87_S0.253081.357
70_A73_V0.248421.332
23_M39_V0.238581.280
26_R29_P0.237071.271
4_V7_G0.23651.268
77_V80_R0.229011.228
52_I71_A0.22851.225
11_V15_T0.220361.182
39_V42_A0.220141.181
39_V43_V0.219641.178
8_M43_V0.214851.152
92_V95_F0.212571.140
84_L88_V0.204611.097
70_A94_A0.204451.096
13_Y20_F0.203791.093
77_V86_L0.202171.084
5_I9_A0.201671.082
78_A87_S0.201661.082
12_T15_T0.199891.072
36_L50_P0.196491.054
66_P95_F0.187821.007
69_I72_L0.186911.002
36_L46_A0.186871.002
23_M26_R0.18570.996
74_A94_A0.185030.992
12_T88_V0.182820.980
15_T18_L0.181440.973
42_A78_A0.179520.963
15_T47_L0.179470.963
7_G11_V0.178980.960
12_T16_R0.17880.959
9_A13_Y0.177160.950
24_R84_L0.176960.949
77_V94_A0.175020.939
34_R38_Y0.174830.938
44_L50_P0.174090.934
10_L93_A0.173590.931
67_Y95_F0.171310.919
70_A95_F0.170990.917
44_L87_S0.170530.915
23_M28_L0.169090.907
5_I15_T0.168490.904
20_F35_F0.1670.896
12_T43_V0.166960.895
11_V17_V0.166120.891
65_N68_L0.165910.890
85_L89_L0.165820.889
30_P33_R0.164610.883
12_T22_L0.164340.881
55_P67_Y0.163350.876
6_L9_A0.160650.862
4_V89_L0.158670.851
11_V14_L0.158440.850
48_V52_I0.158230.849
27_K33_R0.156910.842
42_A46_A0.156130.837
77_V87_S0.156080.837
8_M50_P0.1560.837
6_L72_L0.155460.834
51_S85_L0.155120.832
4_V48_V0.154830.830
22_L32_V0.154660.829
15_T88_V0.153460.823
74_A92_V0.153150.821
43_V50_P0.151180.811
82_R90_A0.149990.804
13_Y25_R0.14990.804
39_V74_A0.149460.802
76_L97_L0.149050.799
16_R56_T0.148370.796
76_L79_L0.147390.790
88_V96_A0.146310.785
65_N72_L0.146110.784
43_V71_A0.145790.782
37_R72_L0.145390.780
30_P34_R0.144020.772
47_L92_V0.143650.770
73_V76_L0.141910.761
82_R87_S0.141540.759
90_A94_A0.140210.752
16_R51_S0.140060.751
74_A78_A0.13980.750
77_V81_T0.138670.744
83_N89_L0.13840.742
32_V69_I0.137650.738
34_R72_L0.136420.732
13_Y21_L0.136240.731
27_K49_V0.136230.731
64_G76_L0.136060.730
18_L34_R0.1360.729
56_T70_A0.135410.726
54_F97_L0.13520.725
76_L93_A0.135030.724
8_M13_Y0.134840.723
43_V64_G0.134450.721
52_I70_A0.134330.720
31_R35_F0.133570.716
46_A50_P0.133390.715
48_V51_S0.1330.713
38_Y72_L0.132720.712
19_P47_L0.132510.711
36_L78_A0.132480.710
54_F93_A0.131980.708
29_P35_F0.131810.707
84_L96_A0.129990.697
23_M44_L0.129550.695
37_R48_V0.129470.694
40_P51_S0.129150.693
30_P37_R0.129080.692
80_R91_G0.128330.688
23_M43_V0.127670.685
94_A97_L0.127640.685
93_A97_L0.12760.684
20_F88_V0.127350.683
20_F49_V0.126990.681
35_F95_F0.126630.679
70_A85_L0.125890.675
54_F82_R0.125640.674
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1u7gA0.90918.70.888
3b9wA0.83847.70.891
3hd6A0.90916.60.894
4hw9A0.91926.30.895
2vv5A0.91924.80.9
2b2hA0.8994.40.901
3rqwA0.50513.70.905
3qe7A0.91923.60.906
3lb6C0.39393.60.906
1rh5B0.34343.40.907
If you are interested in a protein containing this domain,
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