GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF805 - Protein of unknown function (DUF805)
Pfam: PF05656 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 120
Sequences: 1019
Seq/Len: 8.49
HH_delta: 0.912 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
12_K16_W0.545172.714
5_F64_A0.501382.496
9_I13_E0.500282.491
3_F60_I0.493012.454
74_G108_Q0.470912.344
74_G113_R0.451782.249
10_S106_P0.451392.247
98_V102_L0.428412.133
78_W81_L0.411142.047
21_N54_F0.409982.041
9_I68_R0.398931.986
112_N115_G0.392321.953
67_V80_I0.386361.924
71_H77_G0.373071.857
97_I101_Y0.370881.846
92_P95_G0.369731.841
54_F58_L0.362481.805
107_G117_P0.334381.665
77_G80_I0.330711.646
74_G114_Y0.314031.563
60_I68_R0.307841.533
17_F65_L0.291391.451
100_L104_F0.284281.415
8_R115_G0.282851.408
70_L99_L0.267211.330
9_I65_L0.26261.307
10_S117_P0.261711.303
10_S13_E0.256161.275
106_P117_P0.251671.253
101_Y105_L0.24691.229
110_G117_P0.241391.202
66_T103_L0.23931.191
9_I17_F0.233461.162
73_I105_L0.225991.125
81_L92_P0.224521.118
73_I102_L0.221661.104
2_Y61_P0.22151.103
16_W19_L0.22141.102
60_I64_A0.22131.102
108_Q117_P0.217741.084
14_F81_L0.21391.065
106_P109_P0.212481.058
109_P117_P0.212451.058
107_G112_N0.210911.050
5_F63_L0.210431.048
21_N58_L0.210171.046
107_G114_Y0.207871.035
115_G118_P0.206581.028
67_V77_G0.204421.018
10_S118_P0.203091.011
4_N9_I0.201471.003
4_N68_R0.200791.000
15_W73_I0.198710.989
17_F61_P0.19710.981
75_R79_W0.196160.977
23_L27_L0.188550.939
107_G115_G0.18770.934
16_W68_R0.187350.933
77_G92_P0.185870.925
12_K15_W0.185630.924
5_F67_V0.185570.924
82_L95_G0.184670.919
14_F103_L0.182520.909
82_L98_V0.182080.906
64_A68_R0.181850.905
73_I103_L0.181160.902
96_I100_L0.180760.900
13_E65_L0.17770.885
71_H76_S0.17770.885
59_F62_S0.177650.884
7_G112_N0.175680.875
3_F61_P0.174840.870
3_F9_I0.17090.851
26_I33_I0.1690.841
95_G99_L0.168440.839
20_I24_I0.167850.836
2_Y57_L0.166950.831
73_I107_G0.166590.829
4_N103_L0.164070.817
28_L32_S0.163670.815
99_L103_L0.161830.806
21_N25_F0.161090.802
7_G61_P0.160270.798
8_R72_D0.160110.797
76_S79_W0.159620.795
19_L23_L0.159310.793
111_P116_P0.157630.785
26_I30_I0.157490.784
22_I26_I0.156260.778
9_I70_L0.155240.773
63_L80_I0.155020.772
76_S102_L0.153890.766
30_I33_I0.153620.765
65_L68_R0.153110.762
30_I34_I0.152730.760
61_P64_A0.152240.758
99_L102_L0.151850.756
100_L103_L0.151080.752
15_W103_L0.150090.747
66_T70_L0.149350.744
110_G114_Y0.14770.735
75_R113_R0.145430.724
54_F57_L0.14490.721
13_E68_R0.144480.719
70_L77_G0.143740.716
25_F45_S0.143470.714
13_E61_P0.143350.714
9_I71_H0.142370.709
82_L99_L0.142230.708
5_F15_W0.142090.707
25_F54_F0.142060.707
18_F52_I0.140970.702
110_G116_P0.140930.702
79_W108_Q0.140880.701
49_I53_I0.139680.695
8_R114_Y0.138470.689
9_I61_P0.137850.686
17_F21_N0.137550.685
108_Q112_N0.137280.683
61_P65_L0.136970.682
91_I95_G0.134570.670
25_F55_I0.133870.666
29_L52_I0.133290.664
68_R101_Y0.133270.663
10_S107_G0.131850.656
74_G118_P0.130660.650
13_E17_F0.130550.650
108_Q111_P0.130290.649
18_F62_S0.130050.647
82_L92_P0.129830.646
27_L89_L0.128790.641
66_T99_L0.128470.640
107_G110_G0.1280.637
48_S66_T0.127880.637
70_L79_W0.127390.634
32_S52_I0.126970.632
82_L97_I0.126270.629
13_E64_A0.125770.626
10_S115_G0.12560.625
111_P115_G0.12440.619
73_I97_I0.123640.616
102_L105_L0.123230.614
48_S56_L0.123110.613
33_I48_S0.122990.612
15_W64_A0.122160.608
23_L56_L0.121180.603
22_I52_I0.121050.603
22_I25_F0.120840.602
70_L80_I0.120570.600
2_Y5_F0.119370.594
7_G13_E0.118920.592
32_S35_L0.11780.586
95_G98_V0.116620.581
35_L96_I0.115990.577
5_F61_P0.115780.576
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
1fftA0.7519.30.912
2yevA0.7516.50.914
1v54A0.7511.60.92
2gsmA0.759.70.922
3mk7A0.79.50.923
4djkA0.91679.40.923
3s8fA0.758.20.924
2ei4A0.86677.20.927
3hd7B0.30835.70.93
2nwlA0.95835.20.931
If you are interested in a protein containing this domain,
drop us a note and we'll try to predict the structure for you.

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