GREMLIN.BAKERLAB.org

Archive: 2012 - 2013
DUF962 - Protein of unknown function (DUF962)
Pfam: PF06127 (v27) Consensus Sequence
Download Alignment
(Note: includes all positions in family; we filtered this alignment to remove sites that had > 75% gaps before running GREMLIN. )
Length: 95
Sequences: 607
Seq/Len: 6.39
HH_delta: 0.921 (20Jul13)
GREMLIN Results:
Residue pairs sorted by strength in covariance:

Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] gremlin predictions, sequence seperation > 3. The i and j are positions as given in the consensus sequence. Show Scaled Distribution

ij Raw Score Scaled Score
28_V84_P0.425852.817
29_P87_V0.326232.158
25_F90_E0.27741.835
27_G54_G0.272611.803
20_N61_G0.262551.737
22_A26_I0.261851.732
34_S53_V0.249921.653
3_S6_E0.241061.595
17_N20_N0.237181.569
72_F75_N0.232771.540
10_F14_Y0.228061.509
25_F91_L0.226231.496
3_S7_F0.222191.470
60_I65_F0.221091.462
88_W92_L0.217971.442
4_L82_I0.216731.434
27_G57_L0.213191.410
14_Y71_A0.206351.365
87_V91_L0.204071.350
31_I51_F0.20231.338
20_N65_F0.200521.326
55_W59_F0.193171.278
50_V53_V0.19211.271
18_P22_A0.192071.270
10_F71_A0.190171.258
25_F87_V0.187261.239
86_F90_E0.184021.217
56_G60_I0.179791.189
33_F40_A0.176081.165
69_K72_F0.175351.160
55_W58_Q0.175231.159
89_L92_L0.173221.146
39_L44_W0.170761.130
51_F59_F0.166811.103
14_Y74_D0.164121.086
61_G65_F0.163641.082
36_L52_V0.163011.078
55_W70_P0.159881.058
39_L88_W0.159371.054
23_L61_G0.159351.054
32_I41_R0.157781.044
33_F37_L0.157391.041
10_F74_D0.154971.025
4_L85_F0.154661.023
51_F55_W0.15461.023
49_A53_V0.154211.020
18_P40_A0.15241.008
41_R44_W0.151931.005
53_V57_L0.151681.003
10_F79_S0.151491.002
37_L47_A0.151451.002
80_L84_P0.149590.989
72_F83_D0.148950.985
17_N61_G0.145770.964
87_V90_E0.144740.957
16_R49_A0.143170.947
44_W48_L0.142980.946
31_I84_P0.142880.945
36_L88_W0.142880.945
30_L50_V0.141660.937
25_F28_V0.141320.935
63_F71_A0.141260.934
91_L94_R0.140120.927
8_F89_L0.139840.925
19_I22_A0.139820.925
6_E13_S0.139690.924
37_L45_W0.138680.917
18_P50_V0.136760.905
8_F12_L0.136390.902
34_S38_L0.136050.900
32_I84_P0.135070.893
54_G57_L0.133590.884
79_S83_D0.133210.881
26_I44_W0.13210.874
71_A79_S0.131780.872
7_F82_I0.131590.870
39_L43_P0.130460.863
19_I65_F0.130090.860
37_L43_P0.130020.860
7_F86_F0.128620.851
34_S46_L0.128170.848
23_L63_F0.127720.845
28_V86_F0.127350.842
8_F65_F0.127230.842
38_L51_F0.12540.829
11_Y15_H0.124570.824
33_F38_L0.124520.824
48_L52_V0.124320.822
69_K79_S0.12340.816
13_S68_N0.120670.798
81_L84_P0.120110.794
40_A43_P0.119660.791
65_F78_Q0.119580.791
17_N65_F0.119250.789
58_Q75_N0.118920.787
28_V32_I0.118780.786
48_L53_V0.11860.784
82_I85_F0.118370.783
51_F56_G0.117890.780
2_K6_E0.117630.778
31_I53_V0.117590.778
26_I53_V0.117370.776
4_L7_F0.116760.772
5_E9_A0.116660.772
23_L60_I0.115190.762
41_R47_A0.115070.761
50_V54_G0.115030.761
9_A46_L0.114890.760
9_A16_R0.114810.759
17_N63_F0.113250.749
16_R67_K0.113180.749
2_K7_F0.113090.748
23_L27_G0.1130.747
71_A74_D0.112430.744
21_R90_E0.112190.742
31_I72_F0.110580.731
55_W72_F0.11020.729
3_S77_L0.110040.728
36_L41_R0.109820.726
63_F72_F0.109810.726
5_E49_A0.109790.726
17_N27_G0.109650.725
69_K80_L0.109460.724
21_R25_F0.108710.719
85_F89_L0.107890.714
56_G59_F0.107780.713
46_L49_A0.107320.710
18_P43_P0.107130.709
63_F73_F0.107120.709
18_P46_L0.10680.706
14_Y68_N0.106660.706
59_F63_F0.106510.705
78_Q85_F0.10640.704
63_F67_K0.106210.703
10_F83_D0.106170.702
22_A44_W0.106070.702
20_N78_Q0.105940.701
Legend: The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction. These are to be used for relative ranking only.
HHsearch Results:
PDB Cov Prob HH_delta
4f4lA0.61059.30.921
3fvcA0.33683.20.936
4dxwA0.89472.30.94
3h96A0.336820.942
3p57A0.315820.942
3adyA0.33681.90.942
2doaA0.34741.80.944
3rvyA0.98951.70.944
3hd7B0.47371.60.945
4jsnB0.33681.60.945
If you are interested in a protein containing this domain,
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